42 research outputs found
Do dynamic text-only web pages improve usability for PDA users?
No full textText transcoders are proxy–like systems that respond to
requests sent by user’s browsers, strip images, multimedia
objects, JavaScript code and change the page layout. Al-
though the potential benefits of text transcoders as mecha-
nisms to provide alternative and robust user interfaces are
multifaceted, at the moment their benefits on users of small
mobile devices are not clear.
This paper describes an experiment aimed at evaluating us-
ability of web pages used with PDAs when processed by a
text transcoder. Results based on subjective and objective
data show that effectiveness, productivity and satisfaction
can be improved. Furthermore, the needed transformations
are simple to implement, and mostly achievable by many
text transcoders
Do text transcoders improve usability for disabled users?
No full textText transcoders are web--server systems that produce, on the fly, a text-only version of a web page requested by a user of a browser. Although the potential benefits of text transcoders axe multifaceted and discussions on appropriateness of text transcoders to produce accessible versions of web sites are still ongoing, at the moment the impact of transcoded pages on disabled web users has not been scientifically studied yet.This paper describes an experiment aimed at evaluating usability of web pages processed by a text transcoder and used by 29 disabled persons. Results based on subjective and objective data show how usability changes, and which results can be generalized to a wider population
Letter by Violi et al regarding article, "Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization". Circulation. 2010 Aug 17;122(7):e429; author reply e430.
No full textLa forma infranta. La ‘Lezione di Guerra’ di Wilhelm Windelband
No full textThe author offers a critical review of the last, unfinished writings of Wilhelm Windelband on the philosophy
of history. The text, known as the ‘lecture of war,’ is written in the dramatic situation of 1915, just before
the death of the master of the Baden School. The author interprets the ‘lecture’ in relation to the crisis into
which the project of neo-Kantian philosophy of culture was thrown by the World War. Windelband tried to
safeguard his own philosophical perspective and to make a positive contribution to the cultural struggle into
which the Great War had driven all German intellectuals
Goya e il Canale Imperiale d'Aragona: Il tempo di Ramon Pignatelli
No full textInternational audienceDer von der Fortschrittsökonomie in der aufgeklärten Mentalität geforderte Industrialisierungsimpuls spiegelte sich während der Herrschaft von Carlos III. in Ingenieursarbeiten wie dem Bau des Kaiserkanals von Aragón wider. Dieses Aufkommen der politischen Ökonomie als Regierungsinstrument gegen das Diktat der Religion erreichte ihren Höhepunkt im letzten Jahrzehnt dieser Herrschaft, wobei Floridablanca in der Politik, Francisco Cabarrús in der Wirtschaft und Antonio Ponz in den Künsten die wichtigsten Förderer waren.Anhand dieser drei Analysefelder untersucht dieses Buch die Kombination von Faktoren und Umständen, die Ende der 1780er Jahre Ramón Pignatelli mit Francisco de Goya durch einen Malauftrag für den Kaiserkanal aus Aragon verbanden.Die Überprüfung von Archivdokumenten, die Datierung der Unbefleckten Empfängnis, die sich in der Kapelle des Kanals im Jalón-Aquädukt befand, durch die radiologische Analyse der Spuren dieses Gemäldes, die unter dem Porträt von Joaquina Candado Ricarte gefunden wurden, und die Identifizierung des Architekten des Kanals , Fernando Martínez Corcín als Autor der Pläne für das Projekt der Kirche San Fernando de Torrero, haben es uns ermöglicht, den Auftrag Francisco de Goya zuzuordnen, vor dem Tod von Carlos III und den Auswirkungen der Französischen Revolution auf die spanische Politik das Modernisierungsprojekt der Wirtschaft abschneiden.The industrialization impulse demanded by the economy of progress in the enlightened mentality was reflected, during the reign of Carlos III, in engineering works such as the construction of the Imperial Canal of Aragon. This emergence of the political economy as an instrument of government against the dictates of religion had its peak in the last decade of that reign, with Floridablanca in politics, Francisco Cabarrús in the economy and Antonio Ponz in the arts as the main promoters. .Through these three fields of analysis, this book reviews the combination of factors and circumstances that, at the end of the 1780s, linked Ramón Pignatelli with Francisco de Goya through a painting commission for the Imperial Canal. from Aragon.The review of archival documents, the dating of the Immaculate Conception that occupied the chapel of the Canal in the Jalón aqueduct through the radiological analysis of the traces of this painting found under the Portrait of Joaquina Candado Ricarte and the identification of the architect of the Canal, Fernando Martínez Corcín as author of the plans for the project of the church of San Fernando de Torrero, have allowed us to situate the commission to Francisco de Goya, before the death of Carlos III and the impact of the French Revolution on Spanish politics will truncate the modernizing economic project.El impulso industrializador que demandaba la economía del pro- greso en la mentalidad ilustrada se plasmó, durante el reinado de Carlos III, en obras de ingeniería como la construcción del Canal Imperial de Aragón. Esa emergencia de la economía política como instrumento de gobierno frente a los dictados de la religiosidad, tuvo su momento álgido en la última década de ese reinado, con Floridablanca en la política, Francisco Cabarrús en la economía y Antonio Ponz en las artes como principales promotores.A través de estos tres campos de análisis, el presente libro somete a revisión la combinación de factores y circunstancias que, a fina- les de la década de 1780, enlazan a Ramón Pignatelli con Francisco de Goya mediante un encargo de pinturas para el Canal Imperial de Aragón.La revisión de documentos de archivo, la datación de la Inmacula- da Concepción que ocupó la capilla del Canal en el acueducto del Jalón a través del análisis radiológico de las trazas de esta pintura halladas bajo el Retrato de Joaquina Candado Ricarte y la identifi- cación del arquitecto del Canal, Fernando Martínez Corcín como autor de las trazas del proyecto de la iglesia de San Fernando de Torrero, nos han permitido situar el encargo a Francisco de Goya, antes de que la muerte de Carlos III y el impacto de la Revolución Francesa sobre la política española truncaran el proyecto económi- co modernizador.L'impulsion d'industrialisation exigée par l'économie de progrès dans la mentalité éclairée s'est reflétée, sous le règne de Carlos III, dans des travaux d'ingénierie tels que la construction du canal impérial d'Aragon. Cette émergence de l'économie politique comme instrument de gouvernement contre les diktats de la religion a connu son apogée au cours de la dernière décennie de ce règne, avec Floridablanca en politique, Francisco Cabarrús en économie et Antonio Ponz dans les arts comme principaux promoteurs. .À travers ces trois champs d'analyse, ce livre passe en revue la combinaison de facteurs et de circonstances qui, à la fin des années 1780, unirent Ramón Pignatelli à Francisco de Goya à travers une commande de peinture pour le Canal Impérial d'Aragon.L'examen des documents d'archives, la datation de l'Immaculée Conception qui occupait la chapelle du Canal dans l'aqueduc de Jalón à travers l'analyse radiologique des traces de cette peinture trouvée sous le Portrait de Joaquina Candado Ricarte et l'identification de l'architecte du Canal , Fernando Martínez Corcín comme auteur des plans du projet de l'église de San Fernando de Torrero, nous ont permis de situer la commande à Francisco de Goya, avant la mort de Carlos III et l'impact de la Révolution française sur la politique espagnole tronquer le projet économique modernisateur.L'impulso all'industrializzazione richiesto dall'economia del progresso nella mentalità illuminista si riflette, durante il regno di Carlo III, in opere di ingegneria come la costruzione del Canale Imperiale d'Aragona. Questo emergere dell'economia politica come strumento di governo contro i dettami della religione ebbe il suo apice nell'ultimo decennio di quel regno, con Floridablanca in politica, Francisco Cabarrús nell'economia e Antonio Ponz nelle arti come i principali promotori. .Attraverso questi tre campi di analisi, questo libro passa in rassegna la combinazione di fattori e circostanze che, alla fine degli anni Ottanta del Settecento, legarono Ramón Pignatelli a Francisco de Goya attraverso una commissione pittorica per il Canale Imperiale d'Aragona.La revisione dei documenti d'archivio, la datazione dell'Immacolata Concezione che occupava la cappella del Canale nell'acquedotto Jalón attraverso l'analisi radiologica delle tracce di questo dipinto rinvenute sotto il Ritratto di Joaquina Candado Ricarte e l'identificazione dell'architetto del Canale , Fernando Martínez Corcín come autore dei piani per il progetto della chiesa di San Fernando de Torrero, ci hanno permesso di situare la commissione a Francisco de Goya, prima della morte di Carlos III e dell'impatto della Rivoluzione francese sulla politica spagnola troncare il progetto economico modernizzante
Early decrease of oxidative stress by atorvastatin in hypercholesterolaemic patients: Effect on circulating vitamin E
No full textAims: Statins inhibit oxidative stress, but the interplay between cholesterol lowering and antioxidant vitamins is still unclear. Aims of the study were to assess if statins inhibit oxidative stress independently from cholesterol lowering, to assess the behaviour of vitamin E simultaneously with the changes of oxidative stress, to determine in vitro if atorvastatin was able to directly influence platelet-mediated LDL oxidation and vitamin E consumption. Methods and results: In 30 hypercholesterolaemic patients (HC) and 20 healthy subjects (HS), urinary isoprostanes and plasma vitamin E were determined. The HC were randomized to diet or diet plus atorvastatin 10 mg/day. Compared with HS, HC had higher isoprostanes and lower vitamin E levels. The statin-allocated group showed a reduction of isoprostanes after only 3 days (-18.8%, P < 0.01); after 30 days, a stronger reduction of isoprostanes was noted (-37.1%, P < 0.01) whereas an increase of vitamin E (+42%, P < 0.01) and a reduction of cholesterol (-24.9%, P < 0.01) were observed. The diet-allocated group showed a weak decrease of cholesterol after 30 days. In vitro study showed that atorvastatin dose-dependently inhibited platelet-mediated LDL oxidation and isoprostane formation with a mechanism involving NADPH-oxidase. Conclusion: The study provides the first evidence that atorvastatin exerts an early antioxidant effect that could contribute to enhancing circulating vitamin E. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2007
Diritti fondamentali e riparto di giurisdizione
No full textThis paper represents the written version of the author\u27s speech at the Conference held in Palermo on 20th October 2023 on the topic of “Administrative Judge and the Protection of Fundamental Rights”. In particular, the paper addresses the issue of the distribution of jurisdiction in fundamental rights from constitutional categories, through an analysis of the living law.Il presente contributo rappresenta la versione scritta dell’intervento dell’Autore al Convegno tenutosi a Palermo il 20.10.2023 sul tema “Giudice amministrativo e tutela dei diritti fondamentali”. Il lavoro, in particolare, affronta il tema del riparto di giurisdizione in materia di diritti fondamentali a partire dalle categorie costituzionali, attraverso una analisi del diritto vivente
Low-grade endotoxemia is associated with cardiovascular events in community-acquired pneumonia
No full textObjectives: Community-acquired pneumonia (CAP) is associated with low-grade endotoxemia but its relationship with cardiovascular events (CVE) has not been investigated.Methods: We evaluated the incidence of CVE including myocardial infarction, stroke, and cardiovascular death in 523 adult patients hospitalized for CAP. Serum lipopolysaccharide (LPS) and zonulin, a marker of gut permeability, were analyzed in the cohort, that was followed-up during hospitalization and up to 43 months thereafter.Results: During the hospital-stay, 55 patients experienced CVE with a progressive increase from the lowest (0.6%) to highest LPS tertile (23.6%, p < 0.001). Logistic regression analyses showed that higher LPS tertile was independently associated with CVE; LPS significantly correlated with age, hs-CRP and zonulin. In a subgroup of 23 CAP patients, blood E. coli DNA was higher in patients compared to 24 controls and correlated with LPS. During the long-term follow-up, 102 new CVE were registered; the highest tertile of LPS levels was associated with incident CVE; Cox regression analysis showed that LPS tertiles, age, history of CHD, and diabetes independently predicted CVE.Conclusions: In CAP low-grade endotoxemia is associated to short- and long-term risk of CVE. Further study is necessary to assess if lowering LPS by non-absorbable antibiotics may result in improved outcomes. (c) 2023 The Author(s). Published by Elsevier Ltd on behalf of The British Infection Association
Martino Buonocore e il palazzo Carafa della Spina nel Settecento
No full textThe essay explores the figure of Martino Buonocore and his main work, the renovation of the Carafa della Spina palace in Naples. For this work, executed in the 18th century, there have been conflicting interpretations, which tend to attribute its conception to Ferdinando Sanfelice. This hypothesis has been completely debunked by the investigation of primary sources. Crucial to Buonocore’s production is the family collaboration and the sharing of labour in his father Filippo's studio; the latter was the author of the magnificent 18th-century renovation of the palace in Corigliano. Martino was the author of the church of Santa Maria Verticoeli in Naples and had a 20-year commission for the Certosa di Padula. He worked for a long time with Gennaro Maria Carafa, who was to work on the Posillipo casino and the San Domenico palace. This last work will consolidate the long professional and friendly relationship between the prince and the architect.Il saggio esplora la figura di Martino Buonocore e la sua opera principale, la ristrutturazione del palazzo Carafa della Spina a Napoli nel XVIII secolo, per la quale ci sono state interpretazioni contrastanti, protese ad ascriverne l’ideazione a Ferdinando Sanfelice, ipotesi attributiva del tutto fugata dall’indagine sulle fonti primarie. Nella produzione di Martino risulta cruciale la collaborazione familiare e la condivisione delle maestranze coinvolte nella bottega artigiana del padre Filippo, già autore della magnifica rifattione settecentesca del palazzo Corigliano. Nel catalogo delle sue opere emergono la chiesa di Santa Maria Verticoeli a Napoli, l’incarico ventennale per la Certosa di Padula e la lunga collaborazione con Gennaro Maria Carafa, che lo impegnerà nel casino di Posillipo e nel palazzo in San Domenico, opera che consoliderà la lunga relazione professionale e amicale tra il principe e l’architetto
