117,547 research outputs found

    First ethnopharmacobotanical survey about Sardinian endemic species, Italy

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    In questo contributo gli autori presentano i risultati di una prima indagine etnofarmacobotanica che si è sviluppata negli ultimi vent’anni, focalizzando l’attenzione sulle piante endemiche utilizzate nella medicina popolare sarda. Da questo studio emerge che il 4% della flora endemica sarda è impiegata in campo terapeutico principalmente per patologie dell’epidermide e del sistema respiratorio

    Ailanthus altissima (Miller) Swingle as a cause of immunoallergic respiratory manifestations

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    In questo lavoro gli autori mettono in correlazione le concentrazioni aeropolliniche di Ailanthus altissima(Miller) Swingle (Simaroubaceae) rilevate nell’atmosfera della città di Cagliari (Sardegna meridionale, Italia) e del suo hinterland, con le sindromi allergiche causate, in alcuni pazienti atopici, dai pollini di questa pianta. Dalle indagini aerobiologiche è stato possibile mettere in evidenza come le più alte concentrazioni aeropolliniche di ailanto sono state riscontrate nel periodo tra aprile e giugno. Su un campione significativo di 74 pazienti, di sesso ed età diversa, ben 21 soggetti sono risultati positivi ai test allergologici

    Ethnobotanical Comparisons between the Village of Escolca and Lotzorai

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    An ethnobotanical comparison between two small comunities of Sardinia (Escolca and Lotzorai) has been completed. The results indicate the use of a large number of plants for self-medication of easily resolved pathologies. Indices have been applied to identify the phytotherapeutic consensus of the two communes in numerical terms

    ETHNOBOTANICAL COMPARISON BETWEEN THE VILLAGES OF ESCOLCA AND LOTZORAI (SARDINIA, ITALY)

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    An ethnobotanical comparison between two small communities of Sardinia (Escolca and Lotzorai) has been completed. The results indicate the use of a large number of plants for self-medication of easily resolved pathologies. Indices have been applied to identify the phytotherapeutic consensus of the two communes in numerical terms

    Antifungal activity of essential oil from Mentha spicata L. and Mentha pulegium L. growing wild in Sardinia island (Italy)

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    This study aims to evaluate the antifungal activity of Mentha spicata L. and Mentha pulegium L. from Sardinia and to assess their efficacy on virulence factors for Candida albicans, particularly on the inhibition of the germ tube formation. The major compounds of the essential oils were carvone (62.9%) for M. spicata and pulegone (86.2%) for M. pulegium. The essential oil from M. spicata showed a more preeminent effect against Cryptococcus neoformans and the dermatophytes Trichophyton rubrum and T. verrucosum (0.32 μL/mL). Both oils were very effective in inhibiting C. albicans germ tube formation, at doses well below their MIC (0.16 μL/mL)

    Genetic and phytochemical difference between some Indian and Italian plants of Withania somnifera (L.) Dunal

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    The geographical distribution of Withania somnifera (L.) Dunal is quite wide. However, in Italy, this species is very rare and grows spontaneously only in Sicily and in Sardinia. The PCR–RAPD technique has been utilized in this work to determine the genetic relationship among Sicilian, Sardinian and Indian samples and the HPLC analysis of whitaferin A was used as a marker to evaluate the phytochemical differences. The genetic difference between Indian and Sicilian plants of W. somnifera turned out to be smaller than that between Indian and Sardinian plants of this species. The phytochemical analysis as well showed that the Sardinian specimen strongly differed from the Indian and Sicilian ones in its contents of withaferin A. Our results seem to confirm the hypothesis that the Italian populations of this species may not be indigenous but naturalised. Due to the high withaferin A content of the Sardinian samples, these plants could be used as a source for pharmaceutical purposes

    Chemical composition and biological assays of essential oils of Calamintha nepeta (L.) Savi subsp. nepeta (Lamiaceae)

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    Aerial parts of wild Calamintha nepeta (L.) Savi subsp. nepeta growing spontaneously on the Mediterranean coast (Sardinia Island, Italy) and on the Atlantic coast (Portugal) were used as a matrix for the supercritical extraction of volatile oil with CO2. The collected extracts were analysed by GC-FID and GC-MS methods and their compositions were compared with that of the essential oil isolated by hydrodistillation, but the differences were not relevant. A strong chemical variability was observed in the essential oils depending on the origin of the samples. The results showed the presence of two chemotypes of C. nepeta. In all Italian samples, pulegone, piperitenone oxide and piperitenone were the main components (64.4-39.9%; 2.5-19.1%; 6.4-7.7%); conversely, the oil extracted from Portuguese C. nepeta is predominantly composed of isomenthone (35.8-51.3%), 1,8-cineole (21.1-21.4%) and trans-isopulegone (7.8-6.0%). The minimal inhibitory concentration (MIC) and the minimal lethal concentration (MLC) were used to evaluate the antifungal activity of the oils against Candida albicans, Candida tropicalis, Candida krusei, Candida guillermondii, Candida parapsilosis, Cryptococcus neoformans, Trichophyton rubrum, Trichophyton mentagrophytes, Microsporum canis, Microsporum gypseum, Epidermophyton floccosum, Aspergillus niger, Aspergillus fumigatus and Aspergillus flavus. The Italian oil, rich in pulegone, exhibited significant antifungal activity against Aspergillus and dermatophyte strains, with MIC values of 0.32-1.25 L mL-1
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