86,544 research outputs found
Hypertension and anti-hypertensive therapy in Menière's disease
No full textBackground: Endolymphatic hydrops is the main physiological correlate of Menière's disease (MD). The endolymphatic sac expresses aldosterone-regulated proteins analogous to those in nephrons. The aim of the study was to assess the prevalence of hypertension in MD and evaluate a correlation between antihypertensive drugs and the course of the disease.
Methods: 89 patients with definite MD, mean age: 57.2±15.4 years; 48 male (54%). Crises in the last 12 months, the hearing ability (PTA4), the state of the disease (active/stable), symptoms, hypertension, and anti-hypertensive medications were collected.
Results: Fifty-one percent of patients were hypertensive; 77% of hypertensives took chronic antihypertensive therapy: RAAS inhibitory, (25%); diuretics (16%); beta-blockers (15%); association (29%). The disease was active in 38% of the subjects. Hypertensive patients were older (63.8±11.4 vs 50.4±16.2, P=<0.001) and showed a higher PTA4 in both the affected and contralateral ear (60.8±20.5 vs 45.4±20.4, P= 0.0009). There was no significant difference in the prevalence of symptoms or in the detection of endolymphatic hydrops on MRI between hypertensive and normotensive patients. In patients taking antihypertensive therapy, the number of crises was comparable in both patients in therapy with RAAS inhibitor drugs and in patients on beta-blocker therapy. In hypertensive patients on diuretics the number of crises was lower (12.7±7.2 vs 6.3±5.4, P= 0.01).
Conclusion: It is possible that hypertension plays an important role in the development of related symptoms to Meniere's disease. The use of diuretics was associated with reduced clinical manifestations of the disease
Calibration of fractured reservoirs with dynamic data.
No full textPaper 16th Reservoir Simulation Symposium, Houston (TX
Combining two- And three-phase coreflooding experiments for reservoir simulation under WAG practices
No full textEnhanced oil recovery (EOR) processes may often involve simultaneous flow of two or three immiscible fluids inside the reservoir. A precise evaluation of relative permeabilities is critical to quantify multi-phase flow dynamics, assisting improved management and development of oil- and gas- bearing formations. This study illustrates the results of laboratory-scale investigations of multiphase flow on a sandstone reservoir core sample to evaluate relative permeabilities under two- and three-phase (i.e., water, oil, and gas) conditions. We use the ensuing information to simulate WAG injection at reservoir scale. The experiments are conducted at high temperature, consistent with reservoir conditions, to obtain two- (oil/water and oil/gas) and three-phase (oil/water/gas) relative permeabilities through Steady-State (SS) technique. Our laboratory workflow allows for an improved investigation by combining coreflooding experiments with in-situ X-Ray evaluation of local saturation distribution. The latter technique permits to asses slice-averaged phase saturation along the rock core, enabling to compute saturation profiles and average saturations while flooding, thus yielding significant advantages over traditional methodologies based on mass balance. Three-phase steady state (SS) experiments are performed by following diverse saturation paths, and the complete experimental dataset is provided to (a) assess the occurrence of local three-phase saturation conditions and (b) possibly investigate hysteretic effects of relative permeabilities. We evaluate three-phase relative permeabilities across the entire three-phase saturation region by leveraging a Sigmoid-based model (Ranaee et al., 2015). The resulting set of experimental two- and three-phase coreflooding results constitute a unique dataset which is then employed for reservoir simulation studies mimicking WAG injection and results are discussed in comparison with reservoir production under a waterflooding scenario
Robot-assisted fenestration of giant hepatic cysts in posterosuperior segments
No full textBackgroundThe diffusion of the use of robotic surgical platforms, such as the da Vinci Xi Surgical System (R) (Intuitive Surgical, Sunnyvale, CA, USA), has been advocated by several authors to overcome the limitations of laparoscopy in hepatobiliary surgery.MethodsWe reported our experience of robot-assisted fenestration of giant hepatic cysts in posterosuperior segments with the use of indocyanine green fluorescence imaging. We described step by step our surgical technique including the operative room set-up, port placement and robotic instruments.ResultsWe enrolled 11 patients: nine females and two males with a mean age of 65 years (range 52-80 yrs). All procedures were undertaken successfully without intraoperative or postoperative complications. The mean surgical operating time was 125 min. The mean blood loss was 30 ml. The median postoperative stay was two days (range, 1 to 3 days).ConclusionsThe most significant advantage of the robotic approach was the ability to access hepatic cysts close to the diaphragm
Variations on the Author
No full text“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
[Newspaper Clipping: Author Claims Evidence of Second JFK Assassin #1]
No full textNewspaper article titled "Author Claims Evidence of Second JFK Assassin." The article states that author Richard J. Whalen concluded "that there is circumstantial evidence to support the theory of a second assassin in the shooting of President John F. Kennedy.
Also By The Same Author: AKTiveAuthor, a Citation Graph Approach to Name Disambiguation
No full textThe desire for definitive data and the semantic web drive for inference over heterogeneous data sources requires co-reference resolution to be performed on those data. In particular, name disambiguation is required to allow accurate publication lists, citation counts and impact measures to be determined. This paper describes a graph-based approach to author disambiguation on large-scale citation networks. Using self-citation, co-authorship and document source analyses, AKTiveAuthor clusters papers, achieving precision of 0.997 and recall of 0.818 over a test group of eight surname clusters
John F. Kennedy telegram to Roosevelt
No full textJersey Homesteads (later the Borough of Roosevelt) was established in the 1930s as an agro-industrial cooperative community. It was established specifically for urban Jewish garment workers, many of whom had emigrated from Europe. President John F. Kennedy sent a telegram to the citizens of Roosevelt, New Jersey, apologizing for not being able to attend the memorial dedication in honor of former President Franklin Delano Roosevelt. (Jersey Homesteads became Roosevelt in 1945 in honor of the president.) President Kennedy expressed his gratitude to the people of Roosevelt for constructing the memorial, and commented that it will serve as a constant reminder of Roosevelt's good works
Logarithmic variance profiles and the corresponding f-1 spectra of temperature fluctuations in turbulent Rayleigh-Bénard convection
No full textWe report experimental results for the temperature variance 2(z) and the corresponding frequency spectra P(f) in turbulent Rayleigh-Bénard convection (RBC) in a cylindrical sample of aspect ratioT= D/L = 1:00 (D = 1:12 m is the diameter and L = 1:12 m the height). The measurements were conducted in the Rayleigh-number range 1011 < Ra < 1:35 1014 and Pr ' 0:8. For Ra = 1:35x1014, 2(z) could be described well by a logarithmic dependence on the vertical position z in a range of z 1 < z < z 2 with z 1 ' 70 and z 2 = 0:1L. Here L=(2Nu) is the thickness of a thin thermal sublayer adjacent to the horizontal plate where the heat flux (denoted by the Nusselt number Nu) is carried mostly by thermal diffusion. In the log layer, we found that the temperature spectra had a significant frequency range over which P(f) f with close to 1. As Ra decreased, increased so that the log layer became thinner. At Ra = 2:05 1011, z 2 < z 1 and therefore there was no range for a log layer. Correspondingly, the temperature spectrum near the horizontal plate did not have the f1 scaling form either
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