1,721,141 research outputs found

    Modeling CarbonNanoTube-ISFET junction to investigate Electrophysiological Neuronal Activity

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    Carbon nanotubes arranged in vertical alignment and normal direction to the gate insulator of an ion-sensitive field-effect transistor are proposed as electrical interfaces to neurons, and a model of such a system is developed to simulate and analyze the electrical interactions and the induced extracellular neuronal electrical activity. The results pointed out nanotubes act on the amplitude and the shape of the recorded signals and promote an increase in the efficacy of neuronal signal transmission

    Integrated low noise signal conditioning interface for neuroengineering applications

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    the birth of Neuroengineering, a new research field recently introduced by the synergic overlap between neuroscience and electronic engineering disciplines, injected a great enthusiasm in researchers. In fact, it opened a new perspective for addressing complex problems such as the understanding of the brain functions and the development of novel and advanced brain-computers. In this article, we offer a brief overview on implementations of integrated interface systems for neurobiological and electrophysiological in-vitro applications. After, we propose a system, still under development, aimed to achieving some hundreds of input channels. The architecture comprises a low-noise preamplifier stage and exhibits - for each channel - a power consumption of 90.05 μW and a silicon area of about 0.17 mm2. Work is currently in progress to implement a fully integrated recording circuitry
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