1,721,068 research outputs found
Polymer mixtures of anionic and cationic polysaccharides and use thereof. United States Patent 8951991
No full textDescribed in the present application are compositions comprising mixtures of polyanionic polysaccharides and polycationic polysaccharides consisting of oligosaccharide derivatives of chitosan. In the compositions of the invention said mixtures have proven to be soluble in aqueous environments, despite ionic complexes forming between the acid polysaccharides and chitosan derivatives. Said compositions have also demonstrated significant rheological behavior with an unexpected increase in viscosity and viscoelasticity, although the polysaccharides used have relatively low average molecular weights. The said solubility and rheological behavior renders the compositions of the invention particularly advantageous from the biomedical application viewpoint, in particular for viscosupplementation and particularly in the field of articular pathologies and of ophthalmic surgery
IDROGELI DI MISCELE DI POLISACCARIDI PER L'INGEGNERIA TISSUTALE E LA VEICOLAZIONE DI COMPOSTI ATTIVI
No full textLa presente invenzione è relativa a idrogeli (matrici 3D) ottenibili da soluzioni di miscele polimeriche binarie di polisaccaridi acidi e di derivati di polisaccaridi basici, quali i derivati oligosaccaridici del chitosano, opportunamente gelificati con agenti gelificanti ed al loro uso nel campo biomedico
Widespread presence in mammals and high binding specificity of a nuclear protein that recognizes the single-stranded (CCCTAA)n telomeric motif.
No full textHYDROGELE VON POLYSACCHARIDMISCHUNGEN FÜR DAS GEWEBE-ENGINEERING UND ALS WIRKSTOFFTRÄGER. German Patent DE602007004212
No full textThe present invention describes the preparation of hydrogels (or 3D matrices) obtainable from aqueous solutions of mixtures of acid polysaccharides and derivatives of basic polysaccharides, such as oligosaccharide derivatives of chitosan. Said solutions are suitably gelled with either chemical or physical gelling agents with the aim of encapsulating either cells, isolated or in multicellular associations, or pharmacologically active molecules, in solution or suspension, for use in the biomedical and pharmaceutical field
HYDROGELS OF POLYSACCHARIDE MIXTURES FOR TISSUE ENGINEERING AND AS CARRIERS OF ACTIVE COMPOUNDS. European Patent EP2029629
No full textThe present invention describes the preparation of hydrogels (or 3D matrices) obtainable from aqueous solutions of mixtures of acid polysaccharides and derivatives of basic polysaccharides, such as oligosaccharide derivatives of chitosan. Said solutions are suitably gelled with either chemical or physical gelling agents with the aim of encapsulating either cells, isolated or in multicellular associations, or pharmacologically active molecules, in solution or suspension, for use in the biomedical and pharmaceutical field
POLYMERMISCHUNGEN VON ANIONISCHEN UND KATIONISCHEN POLYSACCHARIDEN UND VERWENDUNG DAVON. German Patent DE602007008879
No full textDescribed in the present application are compositions comprising mixtures of polyanionic polysaccharides and polycationic polysaccharides consisting of oligosaccharide derivatives of chitosan. In the compositions of the invention said mixtures have proven to be soluble in aqueous environments, despite ionic complexes forming between the acid polysaccharides and chitosan derivatives. Said compositions have also demonstrated significant rheological behavior with an unexpected increase in viscosity and viscoelasticity, although the polysaccharides used have relatively low average molecular weights. The said solubility and rheological behavior renders the compositions of the invention particularly advantageous from the biomedical application viewpoint, in particular for viscosupplementation and particularly in the field of articular pathologies and of ophthalmic surgery. polyme
3D DOSIMETER AND DOSIMETRIC METHOD USING 3D DOSIMETER
No full text3D dosimetric device and method for the dose verification in radiotherapy and for the quality controls of radiation beams by means of the electron paramagnetic resonance (EPR) reading of the radioinduced signal, in which the dosimetric material consists of a polymeric matrix that incorporates nanometric microporous crystals of inorganic material, characterized in that the microporous polymeric matrix that incorporates nanometric microporous crystals of inorganic material is alginate
MISCELE POLIMERICHE DI POLISACCARIDI ANIONICI E CATIONICI E LORO IMPIEGO
No full textNel presente brevetto sono descritte composizioni comprendenti miscele di polisaccaridi polianionici e policationici costituiti da derivati oligosaccaridici del chitosano. Nelle composizioni dell’invenzione tali miscele si sono dimostrate solubili in ambiente acquoso, nonostante che tra i polisaccaridi acidi ed i derivati del chitosano si formino complessi ionici. Inoltre tali composizioni hanno mostrato un significativo comportamento reologico con un incremento inaspettato della viscosità e visco-elasticità, benché i polisaccaridi impiegati abbiano pesi molecolari medi relativamente bassi. Tutto ciò, solubilità e comportamento reologico, rende le composizioni secondo l’invenzione particolarmente vantaggiose dal punto di vista applicativo biomedico, in particolare nella visco-supplementazione in particolare nel campo delle patologie articolari
POLYMER MIXTURES OF ANIONIC AND CATIONIC POLYSACCHARIDES AND USE THEREOF. European Patent EP2021408
No full textDescribed in the present application are compositions comprising mixtures of polyanionic polysaccharides and polycationic polysaccharides consisting of oligosaccharide derivatives of chitosan. In the compositions of the invention said mixtures have proven to be soluble in aqueous environments, despite ionic complexes forming between the acid polysaccharides and chitosan derivatives. Said compositions have also demonstrated significant rheological behaviour with an unexpected increase in viscosity and viscoelasticity, although the polysaccharides used have relatively low average molecular weights. The said solubility and rheological behaviour renders the compositions of the invention particularly advantageous from the biomedical application viewpoint, in particular for viscosupplementation and particularly in the field of articular pathologies and of ophthalmic surgery
MATERIALI NANOCOMPOSITI FORMATI DA UNA MATRICE POLISACCARIDICA E NANOPARTICELLE METALLICHE, LORO PREPARAZIONE ED USO
No full textNella presente invenzione sono descritti materiali nanocompositi formati da una matrice polimerica consistente in una composizione polisaccaridica tra polisaccaridi neutri o anionici e polisaccaridi cationici ramificati, in cui nanoparticelle metalliche sono disperse uniformemente e stabilizzate. Sfruttando opportune tecniche di gelificazione è possibile ottenere da tali materiali nanocompositi idrogel o, per opportuna disidratazione, matrici tridimensionali non idrate con diverse forme (ad esempio cilindri, microsfere, scaffold, gel a sviluppo superficiale quali film secchi o umidi, fibre). Tali materiali nanocompositi possiedono una marcata attività battericida ad ampio spettro senza però risultare citotossici. Le particolari proprietà antibatteriche associate alla nano-scala delle particelle metalliche e alla presenza di segnali biologici sulle catene polimeriche insieme alla mancanza di citotossicità possono venire sfruttate nello sviluppo di biomateriali di nuova generazione dotati di proprietà antimicrobiche e per svariate altre applicazioni nel campo biomedico, farmaceutico ed alimentare
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