1,721,035 research outputs found
Alterata polarizzazione e topografia delle integrine negli epiteliomi basocellulari e spinocellulari.
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CLEAR ZONE IN OSTEOCLAST FUNCTION - ROLE OF PODOSOMES IN REGULATION OF BONE-RESORBING ACTIVITY
No full textThe adhesion of osteoclasts to the bone matrix is mandatory for bone resorption. Contact of the osteoclast with bone surface induces, in fact, cell polarization and organization of the resorbing apparatus, the so-called "ruffled border." Cell-matrix interaction in osteoclasts is a complex phenomenon resulting from formation of the "clear zone," a cytoplasmic area presenting the adhering plasma membrane, or "sealing membrane." The sealing membrane surrounds the ruffled border and seals the resorbing compartment, namely the extracellular space in which bone resorption takes place. Adhesion at this level occurs via specialized discrete structures, the "podosomes." Podosomes present most of the protein commonly found in focal adhesions, but with a peculiar organization. They are dynamic elements suitable for regulation, according with the functional demand of the cell. Their assembly increases during bone resorption and is regulated by the cytosolic free calcium concentration and the activity of protein kinase C
Structural and functional studies of integrin receptors in cultured human keratinocytes.
No full textThe MSP receptor regulates alpha6beta4 and alpha3beta1 integrins via 14-3-3 proteins in keratinocytes migration
No full textExpression, topography and function of integrin receptors is severely altered in keratinocytes from involved and uninvolved psoriatic skin.
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The integrin heterodimer α3β1 is expressed in skin but not in peripheral blood Sèzary cells.
No full textTHE DISTRIBUTION OF PODOSOMES IN OSTEOCLASTS CULTURED ON BONE LAMINAE - EFFECT OF RETINOL
No full textCytoskeleton and adhesion patterns of cultured chick embryo chondrocytes during cell spreading and Rous sarcoma virus transformation
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