171 research outputs found
High-resolution spatial and temporal evolution of two-dimensional flow structure at a small stream confluence
Full text linkConfluences are recognized as locations within rivers where interaction between incoming flows produces complex hydrodynamic conditions characterized by distinct spatial patterns of mean or turbulent flow. Despite recognition of this hydrodynamic complexity, few studies have mapped in detail spatial patterns of flow at confluences and variation in these patterns over time. Recent developments in Large-Scale Particle Image Velocimetry (LSPIV) have created novel opportunities to explore the spatial and temporal dynamics of flow patterns at confluences. This study uses LSPIV to map two-dimensional flow structure at the water surface and to examine variation in this structure over time. Results show that flow within the confluence is characterized by a large region of flow stagnation develops at the junction apex, a region of low velocities at the downstream junction corner, and a region of merging of the two flow along a mixing interface within the center of the confluence. Interaction between the incoming flows varies over time in the form of episodic pulsing in which one of the two tributaries flows first decelerates and then subsequently accelerates into the confluence. The cause of this pulsing remains uncertain, but it seems to reflect changes in the water-surface pressure-gradient field as the two flows compete for space within the confluence. No large-scale vortices are evident within the mixing interface for the particular flow conditions documented in this study, but such vortices do occur along the margins of the stagnation zone where shearing action between fast-moving and slow-moving fluid is strong. The results of the study provide insight into the time-dependent dynamics of the spatial structure of flow at stream confluences.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2022-12-01The student, Sadia Sabrina, accepted the attached license on 2020-12-08 at 11:35.The student, Sadia Sabrina, submitted this Thesis for approval on 2020-12-08 at 11:38.This Thesis was approved for publication on 2020-12-09 at 13:43.DSpace SAF Submission Ingestion Package generated from Vireo submission #16083 on 2021-03-04 at 16:33:50Made available in DSpace on 2021-03-05T21:47:34Z (GMT). No. of bitstreams: 2
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Previous issue date: 2020-12-09Embargo set by: Seth Robbins for item 117341
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Role of Cytoskeletal Protein, Actin in Various Diseases
No full textCytoskeletal proteins, which are unique to eukaryotic cells, form a three-dimensional niche filling the cytoplasm. It is quite essential for a myriad of cellular processes in higher eukaryotes such as cell movement, stability, and cell to cell interaction. There are primarily three major types of cytoskeletal protein, viz microfilaments/actin filaments, microtubules, and intermediate filaments. The polymerization dynamics of these three proteins are in turn regulated by several other accessory proteins depending upon the functional requirement of the cells. These polymerization dynamics of the protein are also responsible for cellular signaling processes that control the cytokine release during various immune responses against foreign particles. It has been widely known that any aberration that occurs during the polymerization dynamics of these three proteins may be responsible for several diseases. These diseases range from various types of cancer, polycystic ovary syndrome, neuropathological disorders, liver cirrhosis, pulmonary fibrosis, and blistering skin diseases. Many microorganisms that infect specialized cell types have been shown to be highly dependent on host cytoskeletal elements.In this chapter, we try to understand the regulation of the microfilament/actin filament that controls different cellular processes, thereby preventing various disease polymorphisms. We also try to evaluate the interaction dynamics of several cytoskeletal binding drugs in controlling such aberrated cellular process which are in turn responsible for various disease polymorphisms. Through our computational studies we give an insight on the comparative analysis of polymerization of tubulin and actin filaments
Aflatoxin B1 residues in imported and local broiler, s breast and thigh muscle in Kurdistan region
No full textResidues of Aflatoxins and their metabolites might be present in meat and other products of animals receiving Aflatoxin
contaminated feeds which could subsequently create health problems in man. Eighty nine imported (Iran/Khosh pokht);
(Turkey/Yam-tapilic, Lades, Senplic, Kapidac, Kozoa, Oznesilpilic) and (Brazil, hilal, Sadia), and 90 locally produced
(Hoshiar poultry farm, Nihad poultry farm, Hokar poultry farm, Mansoor poultry farm, AL-Shimal poultry house, Mardin
poultry house and AL-Eetimad poultry slaughterhouse) broiler breast and thigh muscle samples were examined for residual
Aflatoxin B1 using ELIZA test. Results revealed that out of 89 imported samples only 21 (23.59%) were positive, but only 2
(2.24%) were rejected, while the remaining 87 samples (97.75%) were acceptable. Concerning the local samples, results
showed that 19 samples (21.11%) were positive, but 10 (11.11%) were rejected, while the remaining 80 samples (88.88%)
were accepted. The public health importance of residual AFB1 in broiler meat samples was discussed
RETRACTED ARTICLE: In vitro and in vivo biocompatibility study of polyacrylate TiO2@Ag coated nanoparticles for the radiation dose enhancement
No full textWe, the Editors and Publisher of the journal Artificial Cells, Nanomedicine, and Biotechnology, have retracted the following article:Ateeque Ur Rehman, Muhammad Hassan, Sadia Bano, Khizir Farooq, Aun Raza & Muhammad Naeem Anjum (2021) In vitro and in vivo biocompatibility study of polyacrylate TiO2@Ag coated nanoparticles for the radiation dose enhancement. Artificial Cells, Nanomedicine, and Biotechnology, 49(1), 185–193, DOI: 10.1080/21691401.2021.1889574Since publication, concerns were raised about the methods and some images in this article. Specifically, some images in Figure 7 have been duplicated and rotated. When approached for an explanation, the authors were unable to provide a satisfactory explanation for this. The corresponding author has been informed of our decision to retract.We have been informed in our decision-making by our policy on publishing ethics and integrity and the COPE guidelines on retractions.The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”
Managerial support, work–family conflict and employee outcomes: an Australian study
Full text linkPurpose – Derived from leader–member exchange theory, this study hypothesises the relationships between work–family related managerial support and affective commitment and job satisfaction, and advocates that these relationships are mediated by work–family conflict. Design/methodology/approach – The model was tested in an Australian manufacturing organisation using survey data from employees, using structural equation modelling in Analysis of Moment Structures (AMOS). Findings – The findings suggest that enhanced work–family related managerial support will decrease work–family conflict, eventually enhancing employees' affective commitment and job satisfaction. Originality/value – This study provides important insights into the impact of managerial support on improvements in employees' work–family conflict, and, in turn, its impact on affective commitment and job satisfaction, in the Australian context. 研究目的 – 源自領導者-成員交換理論，本研究就與工作、家庭有關的管理支援與情感承諾和工作滿足感之間的關係提出假設，並主張工作家庭衝突是引發這些關係的媒介。 研究設計/方法/理念 – 有關的模型使用來自員工的調查數據，並使用AMOS內的結構方程式模式，在澳洲一個製造業組織內被測試。 研究結果 – 研究結果暗示、若加強與工作家庭有關的管理支援，則工作家庭衝突便會減少，而這最後將會增加員工的情感承諾和工作滿足感。 研究的原創性/價值 – 本研究提出了重要的見解，使我們更了解在澳洲的背景下，管理支援對改善僱員工作家庭衝突之作用，進而更明白管理支援對情感承諾和工作滿足感的影響
Can Pakistan Raise More External Debt? A Fiscal Reaction Approach
Full text linkThis study has assessed the role of existing policies in determining the state of debt sus-tainability for the Pakistan economy (1980- June 2019) through fiscal reaction function. This study adds to the literature in two aspects. First, a policy index has been constructed to formu-late a debt-policy interactive term that implies whether or not existing macroeconomic policies contribute in making external debt sustainable in Pakistan. Second, this study has gauged the potential sustainable external debt through in-sample forecast method. The estimated results obtained by the ARDL method show that Pakistan has just entered into a phase of unsustainable debt burden in the long run as fiscal reaction analysis exhibits the weak significant negative relationship between primary balance and external debt to GDP ratio. Moreover, existing mac-roeconomic policies also show a negative association with the primary balance that implies the ineffectiveness of policies in making external debt sustainable for Pakistan. This study suggests that an increase in foreign inflows through remittances or export earnings may improve the debt sustainability state in Pakista
INVOLVEMENT AND COMMUNICATION ON FACE BOOK: EXPLORING INTERACTION PATTERNS OF PERSONALITY AND ADULT ATTACHMENT STYLES
Full text linkThe study is intended to explore individuals’ involvementand interaction on Facebook as an outcome of personality dimensions,and attachment styles. Participants (N=383) Facebook users included 60.3% females with an age range of 18-27 years (means = 22.47±2.91). Results suggested that extraversion (β=.12, p<.05) and neuroticism (β=.15, p<.05) predicted Facebook usage (intensity), and effects of neuroticism is moderated by secure attachment style (β interaction= - .23, p<.01). Social interaction on Facebook was predicted by extraversion (β=.14, p<.05) and the effects was moderated by secure attachment style (β interaction= -.16, p<.05). It is concluded that computer mediated communication on social networking sites is a complex phenomenon and shall be studied as a consequence of interaction between personal and environmental factors
AID VOLATILITY, MACROECONOMIC POLICY AND ECONOMIC GROWTH IN PAKISTAN
No full textLike other developing countries, Pakistan also suffers from low saving base. Historically, foreign aid has played a crucial role in filling the gap between saving and investment in case of Pakistan, albeit with considerable volatility. We analyze the impact of foreign aid and its volatility in on economic growth in Pakistan over the period of 1974-2015; foreign aid effectiveness has been evaluated in the presence of sound macroeconomic policies by constructing an index of macroeconomic policy using principal component method. The study concluded that foreign aid and its volatility has negative impact on economic growth in Pakistan under currently prevailing macroeconomic policies. This study departs from existing studies in two ways. First, Generalized Method of Moments (GMM) approach has been used in this study to control for potential endogenity related to aid inflow. Secondly, aid volatility, measured through Hodrick–Prescott (HP) filter, has been incorporated in aid-growth nexus to gauge its impact of growth performance of the countr
The augmentation of heat transfer in a pipe flow using a swirling perforated twisted (SPT) tape insert
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