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    Chemical Process for Preparing L 17392 (Deglucoteicoplanin) and its Salts

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    The present invention is directed to a chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts with bases and acids by submitting a teicoplanin compound or a teicoplanin-like compound to controlled strong acidic hydrolysis conditions

    Process for Preparing Antibiotic L 17392 (Deglucoteicoplanin)

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    Process for preparing antibiotic L 17392 by catalytically hydrogenating a deglucoteicoplanin ester of formula (I), wherein A, B and Z represent hydrogen atoms, R represents benzyl or substituted benzyl, wherein the phenyl group is substituted with at least a substituent selected from chloro, bromo, fluoro, nitro, (C1-C3)alkyl, (C1-C3)alkoxy and the like, with the exclusion of the tri-nitro phenyl group, or acid addition salts thereof, to catalytic hydrogenolysis in the presence of a poisoned hydrogenation catalyst at a temperature from 10C to 40C and a pressure between ambient pressure and 5 atm, in an inert organic solvent preferably in the presence of a mineral acid

    Chemical Process for Preparing Antibiotic L 17054

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    The present invention is directed to a chemical process for preparing the antibiotic substance denominated antibiotic L 17054 and its pharmaceutically acceptable salts by selectively hydrolizing teicoplanin or a factor or compound thereof with a concentrated strong organic acid

    Chemical Process for Preparing Antibiotic L 17392 (Deglucoteicoplanin) and its Salts

    No full text
    The present invention is directed to a chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts with bases and acids by submitting a teicoplanin compound or a teicoplanin-like compound to controlled strong acidic hydrolysis conditions

    Antibiotic L 17046 and Process for Preparing it

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    The present invention is directed to a new antibiotic substance arbitrarily denominated antibiotic L 17046. The antibiotic substance is obtained from the known antibiotic substance called teicoplanin (formerly teichomycin) by chemical treatment. The new compound possesses antimicrobial activity especially against gram-positive bacteria

    Glycopeptide Antibiotic L 17054

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    The present invention is directed to the essentially pure preparation of an antibiotic substance arbitrarily designated antibiotic L 17054. This antibiotic substance is obtained from the known antibiotic substance named teicoplanin (formerly teichomycin) by chemical treatment. The new compound and the pharmaceutically acceptable salts possess antimicrobial activity

    Ester Derivatives of Antibiotic L 17046

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    The present invention is directed to ester derivatives at the carboxylic function of the glycopeptidic antibiotic substance called antibiotic L 17046 with antimicrobial activity mainly against gram-positive bacteria
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