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Chemical Process for Preparing L 17392 (Deglucoteicoplanin) and its Salts
The present invention is directed to a chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts with bases and acids by submitting a teicoplanin compound or a teicoplanin-like compound to controlled strong acidic hydrolysis conditions
Process for Preparing Antibiotic L 17392 (Deglucoteicoplanin)
Process for preparing antibiotic L 17392 by catalytically hydrogenating a deglucoteicoplanin ester of formula (I), wherein A, B and Z represent hydrogen atoms, R represents benzyl or substituted benzyl, wherein the phenyl group is substituted with at least a substituent selected from chloro, bromo, fluoro, nitro, (C1-C3)alkyl, (C1-C3)alkoxy and the like, with the exclusion of the tri-nitro phenyl group, or acid addition salts thereof, to catalytic hydrogenolysis in the presence of a poisoned hydrogenation catalyst at a temperature from 10C to 40C and a pressure between ambient pressure and 5 atm, in an inert organic solvent preferably in the presence of a mineral acid
Chemical Process for Preparing Antibiotic L 17054
The present invention is directed to a chemical process for preparing the antibiotic substance denominated antibiotic L 17054 and its pharmaceutically acceptable salts by selectively hydrolizing teicoplanin or a factor or compound thereof with a concentrated strong organic acid
Chemical Process for Preparing Antibiotic L 17392 (Deglucoteicoplanin) and its Salts
The present invention is directed to a chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts with bases and acids by submitting a teicoplanin compound or a teicoplanin-like compound to controlled strong acidic hydrolysis conditions
PREPARATION AND TESTING OF N15-ALKYL AND N15,N15-DIALKYL DERIVATIVES OF TEICOPLANIN COMPOUNDS AS BACTERICIDES
PREPARATION OF 13-DE(ACETAMIDOGLUPYRANOSYL)-34-DEOXYTEICOPLANIN DERIVATIVES AS ANTIBACTERIALS
PREPARATION OF DE(ACETYLGLUCOSAMINYL)DIDEHYDRODEOXYTEICOPLANIN DERIVATIVES AS ANTIBIOTICS
Antibiotic L 17046 and Process for Preparing it
The present invention is directed to a new antibiotic substance arbitrarily denominated antibiotic L 17046. The antibiotic substance is obtained from the known antibiotic substance called teicoplanin (formerly teichomycin) by chemical treatment. The new compound possesses antimicrobial activity especially against gram-positive bacteria
Glycopeptide Antibiotic L 17054
The present invention is directed to the essentially pure preparation of an antibiotic substance arbitrarily designated antibiotic L 17054. This antibiotic substance is obtained from the known antibiotic substance named teicoplanin (formerly teichomycin) by chemical treatment. The new compound and the pharmaceutically acceptable salts possess antimicrobial activity
Ester Derivatives of Antibiotic L 17046
The present invention is directed to ester derivatives at the carboxylic function of the glycopeptidic antibiotic substance called antibiotic L 17046 with antimicrobial activity mainly against gram-positive bacteria
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