1,721,110 research outputs found

    Osteoporosi maschile: il ruolo degli estrogeni.

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    L'osteoporosi è un problema rilevante non solo nella donna ma anche nell’ uomo. Molto si conosce sull’osteoporosi nella donna mentre ancora poco nell’uomo. Negli ultimi anni anche nel maschio gli estrogeni hanno acquisito un ruolo sempre maggiore nel metabolismo osseo tanto da essere coinvolti nell’osteoporosi correlata all’età e in quella secondaria a ipogonadismo. Questo comporta modificazioni nella pratica clinica e possibili implicazioni terapeutiche

    Remission of primary hyperparathyroidism after parathyroid adenoma fine needle-aspiration biopsy

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    Fine-needle aspiration biopsy could in some particular circumstances lead to remission of parathyroid adenoma. A case-report

    Estrogens and male reproduction

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    Abstract The role of estrogen on male reproductive function has become clearer in the last decade. During these years the study of the effect of testosterone, estrogen or an aromatase inhibitor in hypogonadal men provided a first evidence of the effects of estrogens in the regulation of gonadotropin secretion. At the same time, the development of a line of transgenic male mice lacking estrogen receptor α, estrogen receptor β or aromatase gene provided further evidence about the role of estrogens not only in the regulation of gonadotropin secretion, but also on the effects of estrogens on testicular function and development. A confirmation of these actions of estrogens came from the observation of naturally occurring mutations of the estrogen receptor and of the aromatase gene in human males. Based on these data it has been demonstrated that estrogens are major regulators of gonadotropin secretion acting both at pituitary and hypotalamic level. The presence in the human reproductive structures of estrogen receptor α, estrogen receptor β and the aromatase enzyme indicates the existence of receptor α, estrogen receptor β or aromatase estrogen actions at this level. Anyway, the precise role of estrogens in testicular development and function and on the regulation of human spermatogenesis has not yet been precisely clarified

    Il ruolo degli estrogeni nel maschio

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    The article summarizes all the aspects related to the role of estrogens in the human mal

    Fratture vertebrali in giovane età da osteoporosi grave in un paziente con sindrome di Kallmann.

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    Le immagini delle fratture vertebrali e della densitometria ossea sono mostrate in un paziente giovane con Sindrome di Kallman

    Congenital estrogen deficiency in men: a new syndrome with different phenotypes; clinical and therapeutic implications in men

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    The report focuses on the role of estrogens in human male, dealing with two human models of congenital estrogen deficiency: estrogen resistance and aromatase deficiency. Similarities and differences of clinical phenotypes of these models are described and progresses of estrogen treatment of aromatase-deficient men are reported. Finally, the putative use of estrogen in men and the use of aromatase inhibitors and antiestrogen for male disorders are discussed

    Densitometria Ossea (DEXA): come interpretarla evitando le trappole

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    Il lavoro è mirato a chiarire le insidie nella valutazione della densitometria ossea , esame radiologico utile nella diagnosi di osteoporos
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