1,720,985 research outputs found
Bartonella Henselae infection associated with Guillan-Barré syndrome
No full textThis is the first report of Guillain-Barré syndrome (GBS) related to Bartonella henselae infection. A 10-year-old girl had difficulty walking and marked myalgia. The search for all causes known to trigger GBS was negative. She was treated with intravenous immunoglobulins and recovered. Because she lived in a rural area and had a history of kitten contact, a specific serology for B. henselae infection was performed and confirmed an ongoing infection. She did not show any clinical typical feature of cat-scratch disease. B. henselae infection should be considered in the wide etiologic spectrum of GB
Human T lymphocyte cell line (Mo) and its subclone (J) produce colony stimulating activity on normal and malignant T cell precursors
No full textConditioned medium from a T-lymphoblastic cell line (Mo) is known to produce factors promoting CFU-GM, BFU-E and CFU-MK In our study we investigated the potential CSA of conditioned media obtained from Mo and its subclone J on normal and malignant lymphoid progenitors of both T and B lineage. Both cell lines release factors inducing a significant increase in number and size of T-lymphoid colonies when compared to standard source of factors (PHA-LCM). On the contrary, they, presented a low CSA on B cell precursors confirming the difficulties in identifying a source of growth and differentiation factors for human B cell ontogeny. This study contributes to the knowledge of biological properties of these tumor cell lines, suggesting the possibility to employ Mo- and J-derived supernatants in vitro for improving growth potential of normal and malignant T cell progenitors
Bartonella henselae and inflammatory bowel disease.
No full textSustained fever and increased thickness of the distal ileum on ultrasound suggested Crohn's disease in an adolescent boy. Bartonella henselae infection was diagnosed by specific serology and the patient recovered. Ileitis could be related to B. henselae infectio
Pseudoinfectious mononucleosis: a presentation of Bartonella henselae infection
No full textSix children presented during one year with clinical features of infectious mononucleosis, but with laboratory findings of leucocytosis with neutrophilia, increased erythrocyte sedimentation rate, and hypergammaglobulinaemia. Serology for Epstein-Barr virus, cytomegalovirus, adenovirus, and Toxoplasma gondii was negative, while anti-Bartonella henselae IgM with high IgG titre (>/=1/1024) was present in all. All children had contact with kittens. No specific treatment was administered and all recovere
High Prevalence of Antibodies to Bartonella henselae among Italian Children without Evidence of Cat Scratch Disease
No full textFew data are available on the seroprevalence of antibodies to Bartonella henselae among children. We retrospectively evaluated the presence of immunoglobulin G and M class antibodies to B. henselae in 508 children living in central Italy who were apparently free of any features suggesting B. henselae infection. We found that B. henselae infection is common among children in central Italy, occurs early in life, is in most cases asymptomatic, and resolves spontaneously
High prevalence of antibodies to Bartonella henselae among Italian children without evidence of cat scratch disease.
No full textFew data are available on the seroprevalence of antibodies to Bartonella henselae among children. We retrospectively evaluated the presence of immunoglobulin G and M class antibodies to B. henselae in 508 children living in central Italy who were apparently free of any features suggesting B. henselae infection. We found that B. henselae infection is common among children in central Italy, occurs early in life, is in most cases asymptomatic, and resolves spontaneously
The Expanded Spectrum of Bartonellosis in Children
No full textBartonella spp are emerging infectious agents; in particular, B henselae infection occurs in early childhood, is generally asymptomatic, and in most cases revolves spontaneously. It may, however, produce a wide spectrum of clinical symptoms, the most frequent feature being the typical CSD. Disseminated atypical B henselae infection may follow CSD after a symptom-fee period or may present de novo; in these cases diagnosis may be difficult because clinical features may mimic a large spectrum of disorders. A careful clinical history researching an intimate contact with a kitten associated with a specific serology and an abdominal ultrasound for typical hepatosplenic involvement may allow a rapid and accurate diagnosis, reassuring the family of the child and avoiding expensive and invasive diagnostic procedures. © 2005 Elsevier Inc. All rights reserved
BARTONELLA HENSELAE INFECTION ASSOCIATED WITH GUILLAIN-BARRÉ SYNDROME
No full textThis is the first report of Guillain-Barré syndrome (GBS) related to Bartonella henselae infection. A 10-year-old girl had difficulty walking and marked myalgia. The search for all causes known to trigger GBS was negative. She was treated with intravenous immunoglobulins and recovered. Because she lived in a rural area and had a history of kitten contact, a specific serology for B. henselae infection was performed and confirmed an ongoing infection. She did not show any clinical typical feature of cat-scratch disease. B. henselae infection should be considered in the wide etiologic spectrum of GBS. © 2005 Lippincott Williams & Wilkins
Novità in tema di discinesia ciliare primaria
No full textNumerosi sono ancora i problemi aperti che ritardano o rendono difficile l’inquadramento diagnostico della discinesia ciliare primaria e poco si conosce sulle reali necessità dei soggetti affetti in termini di monitoraggio e di appropriatezza delle cure.Vengono, pertanto, riferiti i risultati delle ricerche più recenti riguardanti rispettivamente gli elementi che possono farne sospettare la diagnosi (in particolare la presenza di una mancata o ridotta pneumatizzazione dei seni paranasali), il significato della misurazione dell’ossido nitrico nasale (utilizzata come test di screening), i progressi nelle tecniche diagnostiche (in particolare la possibilità di eseguire colture dell’epitelio respiratorio ciliato anche utilizzando campioni prelevati mediante brushing nasale), le nuove conoscenze sull’evoluzione della funzione respiratoria, sulle necessità del suo monitoraggio ed infine le prospettive di sviluppo di terapie geniche mirate al ripristino della funzione ciliare
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