3 research outputs found
Evaluation of cardiovascular risk factors for medical workers of an urban multidisciplinary hospital
No full textAim. To assess the prevalence of various risk factors (RF) for cardiovascular diseases (CVD) among employees of a multi-field hospital (Moscow City Clinical Hospital № 29).Material and methods. We determined blood pressure, weight, height, waist circumference, blood lipid and glucose levels, and used specially created questionnaire. At least 322 medical workers aged >40 years were examined.Results. The average age of the subjects was 51,6+7,8 years, among them 21% of doctors, 47% of nurses; 91% of women. 50% of subjects had arterial hypertension in the history, 40% — high blood pressure >140/90 mm Hg (56% of them regularly received antihypertensive drugs). The frequency of other RF of CVDs was as follows: low physical activity — 74%, hyperlipidemia — 69%, excessive salt intake — 68%, obesity — 43%, unhealthy diet — 37%, smoking — 25%. Among allemployees taking acetylsalicylic acid, 80% took it without invariable indications for this. Among persons with invariable indications for statins, the drug of this class was taken by 11%. When comparing indicators in women of different ages, it was found that the frequency of behavioral RF (unhealthy diet, excessive salt intake, low physical activity) in women <50 years was not significantly different from that in women >50 years; smoking in younger women was higher.Conclusion. A survey of medical workers aged >40 years revealed a high frequency of well-known modified RF of CVDs, especially low physical activity, hyperlipidemia, excessive salt intake, and obesity. The prevalence of arterial hypertension, smoking and unhealthy diet in the studied group were also high, but on average did not exceed the same numbers of general Russian population. We determined high frequency of aspirin intake without invariable indications, and low frequency of statins use in individuals with invariable indications, as well as a low efficacy of drug treatment of arterial hypertension
Особенности детоксикации с участием ферментов микросомального окисления и глутатионзависимых ферментов при псевдотуберкулезе у детей
No full textThere was evaluated detoxication function state by the antipyrine test and glutathione dependent enzymes activity among the children with combined form of middle-degree pseudotuberculosis of sharp smooth tendency. Liver disorder was proven by the clin-ical and biochemical approaches. Our results show that it is desirable to allow detoxication biochemical processes peculiarities un-der Yersinia pseudotuberculosis infection while determining disease prognosis.Проведена комплексная оценка детоксикационной функции по антипириновому тесту и активности глутатионзависимых ферментов у детей, больных комбинированной формой псевдотуберкулеза средней степени тяжести с острым гладким течением. Поражение печени устанавливали по клиническим и биохимическим данным. Особенности биохимических процессов детоксикации, наблюдаемых при инфицировании Yersinia pseudotuberculosis, необходимо принимать во внимание, определяя прогноз заболевания
Молекулярные нарушения мембраны эритроцитов при патологии разного генеза являются типовой реакцией организма: контуры проблемы
No full textGeneral patterns and peculiarities of changes in structure and function of red blood cell’s membrane during pathology of different genesis are considered in the article. Based on literature data and our own investigations one concludes concerning presence of typical molecular disturbances of erythrocyte’s membrane in different diseases. But general character of molecular modification of plasmatic membrane during pathology of different genesis is controversial. Universal mechanisms of structural and functional modification of structure and function of cells’ membrane are considered in details.В статье рассматриваются общие закономерности и особенности изменений структуры и функции мембраны эритроцитов при патологических процессах разного генеза. На основании данных литературы и собственных исследований делается заключение о существовании типовых молекулярных нарушений эритроцитарной мембраны при различных заболеваниях. Обсуждается вопрос о наличии генерализованного характера молекулярной модификации плазматических мембран при патологии разного генеза. Детально рассматриваются универсальные механизмы модификации структуры и функции клеточных мембран
