652 research outputs found
Computational multiscale modelling of FSI in arterial vessels: tissue mechanics and WSS analysis
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Scenario of the organic food market in Europe
No full textScenario analysis is a qualitative tool for strategic policy analysis that enables researchers and policymakers
to support decision making, and a systemic analysis of the main determinants of a business or sector.
In this study, a scenario analysis is developed regarding the future development of the market of organic
food products in Europe. The scenario follows a participatory approach, exploiting potential interactions
among the relevant driving forces, as selected by experts. Network analysis is used to identify the roles of
driving forces in the different scenarios, and the results are discussed in comparison with the main findings
from existing scenarios on the future development of the organic sector
Equivalent stiffness and compliance of curvilinear elastic fibers
No full textIn this paper the mechanical response of curvilinear, anisotropic and inhomogeneous elastic fibers is addressed. A general model accounting for fiber three-dimensional geometry, as well as for shear and torsional effects together with the extensional ones is rationally deduced from the three-dimensional elasticity by means of a constrained approach. Closed-form relationships describing chord-referred equivalent tangent stiffnesses and compliances are obtained, generalizing a number of classical results when non-conventional effects are included. Proposed numerical applications highlight the influence of fiber geometric parameters and shear deformability, enabling also to put
in evidence some limits of usually-employed assumptions. Finally, the fiber mechanical response in a large-displacement regime is
modelled through an incremental formulation. In this context, explicit relationships for tangent and secant equivalent along-the-chord elastic moduli are deduced in the case of planar fibers, leading to powerful and direct relationships, useful for the analysis and the design of advanced composite materials reinforced by curvilinear elastic fibers
Stress and strain localization in stretched collagenous tissues via a multiscale modelling approach
No full textMechanobiology of cells in soft collagenous tissues is highly
affected by both tissue response at the macroscale and stress/strain localization mechanisms due to features at lower scales. In this paper, the macroscale mechanical behavior of soft
collagenous tissues is modeled by a three-levels multiscale approach, based on a multi-step homogenization technique from nano up to the macroscale. Nanoscale effects related to both
intermolecular cross-links and collagen mechanics are accounted for, together with geometric nonlinearities at the microscale. Moreover, an effective submodeling procedure is conceived in order to evaluate the local stress and strain fields at the microscale,
that is around and within cells. Numerical results, obtained by
using an incremental finite element formulation and addressing stretched tendinous tissues, prove consistency and accuracy of the model at both macro and microscale, confirming also the
effectiveness of the multiscale modeling concept for successfully analyzing physiopathological processes in biological tissues
Histology-based arterial mechanics: multiscale modeling of age-dependent tissue remodeling
No full textThe Dalkon Shield Claimants Trust: Paradigm Lost (Or Found)?
No full textIn this Essay, Dean Vairo discusses the policies and procedures governing the Dalkon Shield Claimants Trust After raising questions about the Trust\u27s experience in a theoretical and jurisprudential context Dean Vairo describes the historical development of the Trust and provides a preliminary aosesment of the Trust\u27s performance. Dean Vairo addresses various criticisms of the Trust and calls for a reasoned analysis of the Trust\u27s policies in light of the theoretical questions raised in this Essay to determine whether the Trust should be considered as a model for resolving other mass tort cases
Inelastic damage mechanisms in collagen-rich tissues: multiscale modeling of cross-linked molecules within fibrils
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