1,036 research outputs found
College Belonging: How First-Year and First-Generation Students Navigate Campus Life [Review]
No full textFostering a sense of belonging for students has long been considered a crucial component of retention and success for colleges and universities. However, there is no universal definition of what "belonging" actually is. In College Belonging: How First-Year and First-Generation Students Navitage Campus Life, Lisa M. Nunn (2021) delves into what it means for college students "to belong." Through student interviews during their first two years of college, Nunn explores how students define and experience belonging; in doing so, creating a new perspective on what belonging is and how students achieve (or are gifted) belonging.Johnson, C., & Gansemer-Topf, A. (2022). College Belonging: How First-Year and First-Generation Students Navigate Campus Life: [Review]. Journal of College Orientation, Transition, and Retention, 29(2). https://doi.org/10.24926/jcotr.v29i2.4869Copyright (c) 2022 Clayton Johnson, Dr. Ann Gansemer-Topf. This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. Copyright of all articles published in JCOTR belong to the author(s) and are published under a CC BY-NC license. <br
RIBFIND: a web server for identifying rigid bodies in protein structures and to aid flexible fitting into cryo EM maps
No full textMotivation: To better analyze low-resolution cryo electron microscopy maps of macromolecular assemblies, component atomic structures frequently have to be flexibly fitted into them. Reaching an optimal fit and preventing the fitting process from getting trapped in local minima can be significantly improved by identifying appropriate rigid bodies in the fitted component.
Results: Here we present the RIBFIND server, a tool for identifying rigid bodies in protein structures. The server identifies rigid bodies in proteins by calculating spatial proximity between their secondary structural elements.
Availability: The RIBFIND web server and its standalone program are available at http://ribfind.ismb.lon.ac.uk
Fe2O3/NGr@C- and Co–Co3O4/NGr@C-catalysed hydrogenation of nitroarenes under mild conditions
No full textAn improved hydrogenation of nitroarenes using nano-structured iron- and cobalt-based catalysts is
presented. Modifications of the heterogeneous catalysts by N-doped graphene-flakes are crucial for the
success of selective reductions. The use of polar solvents and basic additives has a significant positive influence
on the rate of reduction of nitroarenes. This allows performing non-noble metal-catalysed hydrogenations
under very mild reaction conditions (e.g. 70 °C and 20 bar). On the basis of the obtained catalytic
results a heterolytic mechanism for the hydrogenation process is postulated, to
Military-Connected Student Academic Success at 4-Year Institutions: A Multi-Institution Study
No full textWe examined how the experiences—academic, financial, social, and personal—and relationship factors of military-connected students attending a 4-year institution are associated with their academic success. This multi-institution study highlights the demographic characteristics, experiences, and campus relationships that are associated with military-connected students’ GPA.This article is published as Williams-Klotz, Denise N. & Gansemer-Topf, Ann M.2017 "Military-Connected Student Academic Success at 4-Year Institutions: A Multi-Institution Study." Journal of College Student Development, 58(7);967-982. Project MUSE, doi:10.1353/csd.2017.0078. Posted with permission.</p
Identifying the Camouflage: Uncovering and Supporting the Transition Experiences of Military and Veteran Students
No full textThis study summarizes the qualitative findings from a multi-institutional study about the college transition experiences of military and veteran students, specifically students’ articulation of their needs. Findings reveal (a) a lack of in-processing, (b) need for community, and (c) institutional invisibility. Using the Student Veteran Transition Model developed by Livingston, Havice, Cawthon, and Flemming (2011) as a guide, four recommendations for institutional practice are provided.This accepted article is published as Williams-Klotz, D. N., & Gansemer-Topf, A. M. (2017). Identifying the Camouflage: Uncovering and Supporting the Transition Experiences of Military and Veteran Students. Journal of The First-Year Experience & Students in Transition, 29(1), 83-98. Posted with permission.</p
Values, Contexts, and Realities: Senior Student Affairs Officers’ Decision-Making During the COVID-19 Pandemic
No full textSenior Student Affairs Officers (SSAOs), whose primary responsibility is the health, safety, and well-being of students, were at the forefront of leading their campuses through the COVID-19 crisis. In Fall 2020 a diverse group of 23 SSAOs was interviewed to understand the contexts and issues that influenced decision-making during the pandemic. A focus on students, alignment with institutional contexts, and financial realities were consistently identified as key influencers of decision-making. Effective decision-making often entails a balancing act of several factors. The implications of this study can be used to inform student affairs practice and the professional development of graduate students and future and current SSAOs.This accepted article is published as Gansemer-Topf, A. M. (2022). Values, Contexts, and Realities: Senior Student Affairs Officers’ Decision-Making During the COVID-19 Pandemic. American Behavioral Scientist, 0(0). https://doi.org/10.1177/00027642221118275. Posted with permission
The Power in Groups: Using Cluster Analysis to Critically Quantify Women’s STEM Enrollment
No full textDespite efforts to close the gender gap in science, technology, engineering, and math (STEM), disparities still exist, especially in math intensive STEM (MISTEM) majors. Females and males receive similar academic preparation and overall, perform similarly, yet females continue to enroll in STEM majors less frequently than men. In examining academic preparation, most research considers performance measures individually, ignoring the possible interrelationships between these measures. We address this problem by using hierarchical agglomerative clustering – a statistical technique which allows for identifying groups (i.e., clusters) of students who are similar in multiple factors. We first apply this technique to readily available institutional data to determine if we could identify distinct groups. Results illustrated that it was possible to identify nine unique groups. We then examined differences in STEM enrollment by group and by gender. We found that the proportion of females differed by group, and the gap between males and females also varied by group. Overall, males enrolled in STEM at a higher proportion than females and did so regardless of the strength of their academic preparation. Our results provide a novel yet feasible approach to examining gender differences in STEM enrollment in postsecondary education.This article is published as Gansemer-Topf, Ann et al. "The Power in Groups: Using Cluster Analysis to Critically Quantify Women’s STEM Enrollment" In Advances in Research in STEM Education, edited by Associate Kalogiannakis, Maria Ampartzaki. London: IntechOpen, 2022. 10.5772/intechopen.102881. © 2022 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution 3.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
Investigations on the functions ot "ten-1" during embryonic development in "Caenorhabditis" elegans
No full textTeneurins are a family of phylogenetically conserved proteins. Their most prominent site of expression is the nervous system. Investigations on the expression pattern in vertebrates and invertebrates also revealed the importance for teneurins at sites of morphogenesis during embryonic development. Nevertheless, the function of teneurins remains to be discovered. Teneurins are type II transmembrane proteins. The mechanism of action of teneurins involves the translocation of the intracellular domain into the nucleus. It is postulated that the release of the intracellular domain requires several proteolytic events in the extracellular part, the transmembrane domain and at the cytosolic part. The stimulus of these events is unclear, but there is evidence for homophilic interactions between the teneurins.
The advantage of C. elegans as a model organism to investigate the function and mechanism of action of teneurins is that the C. elegans genome codes only for a single ortholog of the vertebrate teneurins. Two different promoters give rise to at least two different transcript versions. The promoters show distinct patterns of activity in the mesoderm and in the ectoderm of the worm. Two independent deletion mutants are characterized as null mutations. Knock-down by RNAi and analysis of the null mutants revealed that ten-1 is essential for embryonic development but also for postembryonic events like larval development and reproduction. Interestingly, investigations on potential genetic interaction partners of ten-1 uncovered functional redundancy between ten-1 and basement membrane associated genes coding for homologs of integrin, dystroglycan, laminin, nidogen and perlecan. Co-staining of chicken teneurin and laminin in some tissues during embryonic development might point to an evolutionary conserved function of teneurins associated with the basement membrane.
In this study I used a genome wide approach to obtain a comprehensive list of potential genetic interaction partners of ten-1. I characterized the interaction with phy-1 in more detail. phy-1 is conserved among the phyla and codes for the catalytical domain of the collagen-modifying enzyme prolyl 4-hydroxylase. I found that loss of phy-1 in the ten-1 null mutant background enhances embryonic lethality significantly. Worms die during late elongation because of loss of connectivity between muscles, epidermis and the separating basement membrane. In addition, I present evidence that the function of PHY-1 modifying basement membrane collagen IV is conserved also in C. elegans
Gefangen im eigenen Ich: Ein psychoanalytischer Vergleich von E.T.A. Hoffmanns \u3cem\u3eDer Sandmann\u3c/em\u3e und \u3cem\u3eDer goldne Topf\u3c/em\u3e
No full textThis thesis is a comparative study of two major works by the German author E.T.A. Hoffmann, Der Sandmann (1818) and Der goldne Topf (1819). Der Sandmann has been analyzed under the filter of psychoanalysis by Freud himself. The goal of this thesis was to analyze whether a psychoanalytical approach can be extended to other works by Hoffmann, showing the same underlying structures even though the content seems to differ widely between the two works at first glance. Der goldne Topf is the text that I chose to compare to Der Sandmann, as both texts tell the story of a student who is caught in a life between reality and fantasy.
Freud\u27s analysis of Der Sandmann is almost completely based on the role of the father in the text. The strongest difficulty in showing the same underlying motivation for the two protagonists, Anselmus and Nathanael, to choose fantasy over reality, death over life, is that there is no apparent father figure in Der goldne Topf. However, by interpreting the two texts on the basis of Freud\u27s psychoanalysis, it can be shown that a father figure is indeed present in both texts, even though it might not seem like it at first.
In chapter 1 of this thesis, I will give an overview over those parts of Freud\u27s theory, which will be of importance in the analyses of the two selected works by Hoffmann, namely narcissism, the oedipus complex and the analysis of dreams. In chapter 2, I interpret Der Sandmann and in chapter 3, Der goldne Topf is analyzed, applying the same theories as far as possible. Finally, in chapter 4, I compare the two works, and I show that many features of the texts can be matched up on the basis of this theory, including the role of the father. So far, Der goldne Topf has never been analyzed exclusively on the basis of Freud\u27s psychoanalysis before and, therefore, the findings of this thesis provide new insights for research on the two texts and on E.T.A. Hoffmann in general
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