1,590 research outputs found
Numerical analysis of an anomalous current assisted by locally generated deep traps in pn junctions
No full textThe Teshima Museum of Art by Ryue Nishizawa and Rei Naito
No full text[EN] The Museum of art of Teshima by the architect Ryue Nishizawa and the artist Rei Naito is a delicate work where nature, art and architecture are fused together. The museum represents what is shown, the image of a falling bead of water that is identifi ed in the exhibition “Matrix” by Naito, a metaphorical celebration of water as the beginning of life. Nishizawa models this exquisite fi gure using an oscillating shell, hanging in the air 40 X 60 m and 25 cm thick, 4.25 m from the fl oor at a highest point on which two luminescent glazes are carried out. It is a solemn and contemplative museum rooted in the depths of Japanese culture.[ES] El Museo de Arte de Teshima del arquitecto Ryue Nishizawa y la artista Rei Naito es un frágil trabajo donde se funden naturaleza, arte y arquitectura. El museo representa aquello que expone, la imagen de una gota de agua cayendo que se identifica con la muestra “Matrix” de Naito, una celebración metafórica del agua como principio de vida. Nishizawa modela esta exquisita fi gura recurriendo a una cáscara oscilante, tendida al aire, de 40x60 m y 25 cm de espesor, a 4,25 m del suelo, sobre la que se practican dos veladuras luminiscentes. Se trata de un museo contemplativo y solemne arraigado en las raíces de la profunda cultura japonesa.Oficina De Ryue Nishizawa, A. (2011). Teshima Art Museum en la isla de Teshima. Japón. EN BLANCO. Revista de Arquitectura. 3(7):20-29. https://doi.org/10.4995/eb.2011.6911SWORD20293
Knowledge Curation in a Developer Community: A Study of Stack Overflow and Mailing Lists
No full text<p>This file was closed as a result of some issues with the data. Please visit the following link to have access to the updated version of the information. </p>
<p>https://zenodo.org/record/47484</p>
<p>This PostgreSQL dump file contains the data from Stack Overflow r-tag and the R-help mailing list. The data is framed between 2008 and 2013. It is part of "Knowledge Curation in a Developer Community: A Study of Stack Overflow and Mailing Lists" by Carlos Gómez Teshima (2015 MSc. Thesis), and "How the R Community Creates and Curates Knowledge" by Alexey Zagalsky, Carlos Gómez Teshima, Daniel M. German, Margaret-Anne Storey, Germán Poo-Caamaño (MSR 2016 paper).</p>
Corrigendum: The evolution of extreme shell shape variation in the land snail Ainohelix editha: A phylogeny and hybrid zone analysis (Molecular Ecology (2003) 12 (1869-1878))
No full textTeshima H, Davison A, Kuwahara Y, Yokoyama J, Chiba S, Fukuda T, Ogimura H, Kawata M (2003) The evolution of extreme shell shape variation in the land snail Ainohelix editha: a phylogeny and hybrid zone analysis. Molecular Ecology, 12, 1869–1878.On page 1877, Fig. 10(d) is mislabelled as:‘Helicigona lapicida from Sicily’.but should read:‘Marmorana scabriuscula from Erice, Sicily’
The MAGIC II gamma-ray stereoscopic telescope system.
No full textAbstract
MAGIC-II is a stereoscopic system of imaging atmospheric Cherenkov telescopes (IACT) with the two largest dishes in the world. It is located in the Canary island of La Palma. The second 17 m diameter telescope is currently under commissioning. MAGIC with its large reflector area, high quantum efficiency photomultipliers, optical signal transmission and fast digitization, will benefit from an improved shower reconstruction and increased background rejection thanks to the simultaneous observation by using two telescopes. Compared with the single MAGIC telescope, the new system will offer an improvement of 20% in the angular resolution and an enhancement from 25% to 15% in the energy resolution, above few hundreds GeV. It is also expected that the sensitivity improves by factor ∼2–3, reaching 1% of the Crab nebula flux in the full energy range (60 Gev–20 TeV)
Mesoscopic CH3NH3PbI3/TiO2 Heterojunction Solar Cells
No full textWe report for the first time on a hole conductor-free mesoscopic methylammonium lead iodide (CH3NH3PbI3) perovskite/TiO2 heterojunction solar cell, produced by deposition of perovskite nanoparticles from a solution of CH3NH3I and PbI2 in γ-butyrolactone on a 400 nm thick film of TiO2 (anatase) nanosheets exposing (001) facets. A gold film was evaporated on top of the CH3NH3PbI3 as a back contact. Importantly, the CH3NH3PbI3 nanoparticles assume here simultaneously the roles of both light harvester and hole conductor, rendering superfluous the use of an additional hole transporting material. The simple mesoscopic CH3NH3PbI3/TiO2 heterojunction solar cell shows impressive photovoltaic performance, with short-circuit photocurrent Jsc= 16.1 mA/cm2, open-circuit photovoltage Voc = 0.631 V, and a fill factor FF = 0.57, corresponding to a light to electric power conversion efficiency (PCE) of 5.5% under standard AM 1.5 solar light of 1000 W/m2 intensity. At a lower light intensity of 100W/m2, a PCE of 7.3% was measured. The advent of such simple solution-processed mesoscopic heterojunction solar cells paves the way to realize low-cost, high-efficiency solar cells
MT-7716, a novel selective nonpeptidergic NOP receptor agonist, effectively blocks ethanol-induced increase in GABAergic transmission in the rat central amygdala.
No full textThe GABAergic system in the central amygdala (CeA) plays a major role in ethanol dependence and the anxiogenic-like response to ethanol withdrawal. A large body of evidence shows that Nociceptin/Orphanin FQ (N/OFQ) regulates ethanol intake and anxiety-like behavior. In the rat, ethanol significantly augments CeA GABA release, whereas N/OFQ diminishes it. Using electrophysiological techniques in an in vitro slice preparation, in this study we investigated the effects of a nonpeptidergic NOP receptor agonist, MT-7716 [(R)-2-3-[1-(Acenaphthen-1-yl)piperidin-4-yl]-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl-N-methylacetamide hydrochloride hydrate], and its interaction with ethanol on GABAergic transmission in CeA slices of naïve rats. We found that MT-7716 dose-dependently (100-1000 nM) diminished evoked GABAA receptor-mediated inhibitory postsynaptic potentials (IPSPs) and increased paired-pulse facilitation (PPF) ratio of these evoked IPSPs, suggesting a presynaptic site of action of the MT-7716 by decreasing GABA release at CeA synapses. The presynaptic action of MT-7716 was also supported by the significant decrease in the frequency of miniature inhibitory postsynaptic currents (mIPSCs) induced by the nociceptin receptor (NOP) agonist. Interestingly, MT-7716 prevented the ethanol-induced augmentation of evoked IPSPs. A putative selective NOP antagonist, [Nphe1]Nociceptin(1-13)NH2, totally prevented the MT-7716-induced inhibition of IPSP amplitudes indicating that MT-7716 exerts its effect through NOPs. These data provide support for an interaction between the nociceptin and GABAergic systems in the CeA and for the anti-alcohol properties of the NOP activation. The development of a synthetic nonpeptidergic NOP receptor agonist such as MT-7716 may represent a useful therapeutic target for alcoholism
NOP-related mechanisms in substance use disorders
No full textNociceptin/orphanin FQ (N/OFQ) is a 17 amino acid peptide that was deorphanized in 1995 and has been widely studied since. The role of the N/OFQ system in drug abuse has attracted researchers’ attention since its initial discovery. The first two scientific papers describing the effect of intracranial injection of N/OFQ appeared 20 years ago and reported efficacy of the peptide in attenuating alcohol intake, whereas heroin self-administration was insensitive. Since then more than 100 scientific articles investigating the role of the N/OFQ and N/OFQ receptor (NOP) system in drug abuse have been published. The present article provides an historical overview of the advances in the field with focus on three major elements. First, the most robust data supportive of the efficacy of NOP agonists in treating drug abuse come from studies in the field of alcohol research, followed by psychostimulant and opioid research. In contrast, activation of NOP appears to facilitate nicotine consumption. Second, emerging data challenge the assumption that activation of NOP is the most appropriate strategy to attenuate consumption of substances of abuse. This assumption is based first on the observation that animals carrying an overexpression of NOP system components are more prone to consume substances of abuse, whereas NOP knockout rats are less motivated to self-administer heroin, alcohol, and cocaine. Third, administration of NOP antagonists also reduces alcohol consumption. In addition, NOP blockade reduces nicotine self-administration. Hypothetical mechanisms explaining this apparent paradox are discussed. Finally, we focus on the possibility that co-activation of NOP and mu opioid (MOP) receptors is an alternative strategy, readily testable in the clinic, to reduce the consumption of psychostimulants, opiates, and, possibly, alcohol
Zen Buddhist Influence on Makuya Teaching, or “Tabernacle of Christ”
No full textMakuya, or “Tabernacle of Christ” is a Japanese new religious movement and a neo-Christian religion with some Zionist elements. Its founder, businessman Teshima Ikurō (1910–1973), had samurai ancestors. In his youth, he was baptized and joined the non-church movement — Japanese Christians who reject the church and seek to connect with God through a thorough study of the Holy Scriptures. Scholars agree that, firstly, the Makuya teaching continues and develops the ideas of the non-church movement, and secondly, that, like other Japanese Christian organizations, Makuya is significantly influenced by Japanese culture and is primarily its product. Makuya continues the non-church movement as its adherents consider the interpretation of the Holy Scripture the main occupation that allows a person to come to God. Just like the non-church believers, Makuya followers accept the hypothesis of a common origin of the Japanese and the Jews. They also consider Judaism more in line with the original teachings of Jesus Christ than Christianity, which has been distorted by translations of the Bible into Greek and other languages and church institutions. The originality of Makuya teaching, among other things, is determined by such practices as “speaking in tongues”, divine healing, walking on fire, etc. An overview of the life of Teshima Ikurō , the history of the formation of his teaching and the Makuya movement, as well as an analysis of Teshima’s sermons show that some ideas of Zen Buddhism can be traced in his worldview and the Makuya teaching based on it. Two sermons by Teshima Ikurō are analyzed: one where he interprets Psalm 90 (“The Prayer of Moses, the Man of God”), as well as a verse from the Gospel of John. Teshima talks about life, death, the perception of time, and the meeting of person with God. Just like Zen authors, Teshima Ikurō considers the goal of the believer to cast aside illusions and gain true vision. According to the basic postulates of Zen Buddhism, the ascetic gains enlightenment and thereby leaves the endless circle of births and deaths, realizes the non-duality of the world. For Teshima Ikurō , the meeting of a person with God becomes an analogue of enlightenment, after which a person similarly ceases to feel enslaved by time and finds himself in eternity
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