3,945 research outputs found
Letter to the editor. Distribution of genomic breakpoints in chronic myeloid leukemia: analysis of 308 patients
No full textLetter to the EditorD M Ross, M O'Hely, P A Bartley, P Dang, J Score, J M Goyne, M Sobrinho-Simoes, N C P Cross, J V Melo, T P Speed, T P Hughes, and A A Morle
Aquarelle de M. Simoes da Fonseca représentant un lécythe attique conservé au Louvre
No full textCollignon Maxime. Aquarelle de M. Simoes da Fonseca représentant un lécythe attique conservé au Louvre. In: Comptes rendus des séances de l'Académie des Inscriptions et Belles-Lettres, 49ᵉ année, N. 1, 1905. p. 137
More on weak alpha-openness
No full textIn [6] the authors, introduced the notion of weak α-openness and
investigated its fundamental properties. In this paper we investigate some
more properties of this type of openness. In this connection, we obtain a
new decomposition of α-openness and it is also shown that weakly α-open
bijections preserve clopen sets
Comparison of conventional and hybrid modulus press-fit proximal femoral prostheses
No full textThe aim of the this study was to compare the load transfer mechanisms of a standard press-fit proximal femoral prosthesis fabricated from three conventional implant materials, cobalt- chrome, titanium and an 'isoelastic' material with that produced by a hybrid modulus prosthesis using the finite element method In particular, both the periosteal and the endosteal bone stresses were examined.Comparison of the results from the three conventional implant materials were similar to those reported in the literature, with the isoelastic prosthesis producing the least stress shielding of the proximal medial femur and the stiffer implant materials producing low proximal medial interface pressures and cancellous bone stress distributions. The hybrid prosthesis combined these features to produce, overall, the most favourable periosteal and endosteal stress distributions. However, all of the prostheses produced stresses which approach or exceeded the fatigue strength of the supporting cancellous bone suggesting that all would have high migration rates and correspondingly high rates of late aseptic loosening
European Thyroid Association Guidelines regarding Thyroid Nodule Molecular Fine-Needle Aspiration Cytology Diagnostics
No full textMolecular fine-needle aspiration (FNA) cytology diagnostics has the potential to address the inherent limitation of FNA cytology which is an indeterminate (atypia of undetermined significance/follicular lesion of undetermined significance follicular neoplasm) cytology. Because of the emerging role of molecular FNA cytology diagnostics, the European Thyroid Association convened a panel of international experts to review methodological aspects, indications, results, and limitations of molecular FNA cytology diagnostics. The panel reviewed the evidence for the diagnostic value of mutation panel assessment (including at least BRAF, NRAS, HRAS, KRAS, PAX8/PPARG, RET/PTC) of targeted next generation sequencing and of a microarray gene expression classifier (GEC) test in the diagnostic assessment of an indeterminate cytology thyroid nodule. Moreover, possible surgical consequences of molecular FNA diagnostic results of thyroid nodules and the evidence that analysis of a molecular FNA diagnostic panel of somatic mutations or a microarray GEC test can alter the follow-up were reviewed. Molecular tests may help clinicians to drive patient care and the surgical decision if the analysis is performed in specialized laboratories. These molecular tests require standardization of performance characteristics and appropriate calibration as well as analytic validation before clinical interpretation. (C) 2017 European Thyroid Association Published by S. Karger AG, Base
Negotiating for meaning: Papers on foreign language teaching and testing
No full textPapers from a conference on language teaching and testing are grouped in four sections. The first contains a foreword by Dale A. Koike and Antonio R. M. Simoes. The second, on research in second/foreign language teaching, includes the following: "Second Language Learning and Evaluation: From Theory to Classroom Practice" (Sandra J. Savignon); "What Should Portuguese Language Teaching Do About Grammar? Current Trends in the Teaching of Spanish" (Bill Vanpatten); "The Politics of Methodology: Recent Trends and the Teaching of 'Other' Languages" (Diane Musumeci); and "Recent Research on Second Language Learners: Beliefs and Anxiety" (Elaine K. Horwitz). Section three, on reading in a foreign language, presents: "Reading as a Classroom Activity: Theory and Techniques" (Richard Kern, Janet Swaffar, Dolly Young); and "Teaching and Testing an Expository Text" (James F. Lee). The fourth section focuses on Portuguese language teaching for Spanish speakers, with: "Nasal Vowels, the Case of Brazilian Portuguese and Spanish: Description and Classroom Application" (Antonio R. M. Simoes); and "Evaluating Portuguese Performance of Spanish-Speaking Students" (John B. Jenson). A brief text in Portuguese is appended. (MSE
Including detonations in industrial safety and risk assessments
No full textThe common rift between academia and industry has existed in all fields of engineering. However, ultimately that can be seen as more of a lag; it is not so much a question of academia research, which ends up finding its way into the practical world of industry years if not decades later. On the topic of detonations or Vapor Cloud Explosions (VCE), this is indeed a true statement. A little more than a decade ago the common belief in the chemical process industry was that detonations were not possible unless you had some very reactive process materials such as hydrogen or acetylene. When some industry and consulting experts began to challenge this view, they soon found out that a more common and less reactive process material such as ethylene could in fact be made to detonate as well. The key was that the environment had to be just right for an ignited flame to accelerate and transition to a detonation. In fact, academia had known this since the early 1960s and so the question remains, what else can we learn?
Industry has retuned itself and made use of a several common explosion modeling tools which for some can be made to predict detonations. In others, they must be inferred and only very knowledgeable users can determine detonations. This paper will review the basics of detonations, the academic perspective and the industrial applications. Additionally, several of the various and commonly used models for explosion prediction will be reviewed, in the light of detonation
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