203 research outputs found

    Grain trade in Early modern Mantua and Venice: The role of Ashkenazi and Italian Jews

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    The economic role of Ashkenazi and Italian Jews in early modern Italy is traditionally associated with money-lending and second-hand goods retailing. Yet, fiscal and notarial sources show how beneath the surface of the charters signed between the minority and the local authorities, their business was far more diversified. In the northern and central Peninsula Jews had built a strong network based on endogenous and exogenous trust which permitted them to also engage in (inter)regional trade. From the early sixteenth century, when the establishment of the ghettos and changes in the economic system made banking far less lucrative, trading in commodities became a profitable alternative. The case studies of Mantua and the Venetian state show how this process was also strictly intertwined with the local political environment, as Jews had to resort to different sorts of informal and formal relationships with local power structures in order to take part in the grain trade

    Plasma cortisol concentration following breakfasts of different composition in healthy subjects

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    We measured plasma cortisol concentrations following breakfasts of different fat:carbohydrate ratio in 23 healthy subjects. A meal-related peak of plasma cortisol concentration was not found, as well as any difference in plasma cortisol levels following the two meals. Since the two meals elicited plasma glucose and plasma insulin levels which were significantly different, it is suggested that plasma cortisol is not acutely affected by ambient glucose and insulin concentrations. The same results were found when the study group was subdivided in nonobese (n = 13) and obese (Body Mass Index greater than n = 10), thus confirming the previous statement in the presence of different body weights

    Effectiveness of Fully Customized Lingual Orthodontic Treatment: A Retrospective Pilot Study

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    Objective: To investigate the effectiveness of Suresmile® lingual therapy on torque, tip, and rotations measures through digital evaluation of planning and post-treatment digital models. Material and Methods: A sample of 12 Caucasian adult patients (4 men; mean age 30.6 years ± 3.9 and 8 women; mean age 31.4 years ± 4.5) treated with the Suresmile® lingual orthodontic technique was retrospectively selected, regardless of the type of malocclusion. Digital planning was performed with Suresmile® software, while lingual therapy was accomplished with interactive self-ligating lingual brackets and customized Suresmile® arches. First, digital models of planning and post-treatment digital models were compared using VAM software (and the discrepancies were analyzed through MANOVA and four multivariate. Then, Tukey and Bonferroni's post-hoc tests are performed. Results: The accuracy average values are 60.11 ± 27.67% for torque, 53.52 ± 27.37% for tip and 59.19 ± 26.42% for rotation, while for inaccuracy values are 2.72° ± 2.23° for torque, 2.98° ± 2.16° for tip and 3.58° ± 3.29° for rotation. No significant differences have been recorded evaluating different sectors of both arches. Conclusion: This retrospective preliminary study highlight how overcorrections, especially in the Suresmile lingual technique, should be performed during orthodontic planning. Moreover, the study gets bases for further, more structured future studies that should involve larger and more homogeneous samples

    Coupled computational fluid dynamics and computational thermodynamics simulations for fission product retention and release: A molten salt fast reactor application

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    This study presents a computational capability for fission product retention and release in two-phase, multi-species systems representing Molten Salt Reactors (MSR) with coupled thermal-hydraulics and fuel coolant chemical behaviours. This is demonstrated through four simulated cases centred on the proposed Molten Salt Fast Reactor (MSFR). This is achieved by two-way coupling the Computational Fluid Dynamics (CFD) code OpenFOAM and the Computational Thermodynamics (CT) code Thermochimica, using the Joint Research Centre Molten Salt Database (JRCMSD). Local chemical equilibrium is assumed, implying that chemical kinetics are predominantly governed by mass transport. Four simulations address normal operating conditions, exploring: (i) dilution of fission products injected within the molten salt coolant, (ii) molten salt coolant evaporation rate, (iii) release of radioactive gaseous species, (iv) shifts in the UF4/UF3 ratio, and (v) comparison of vapour pressures of gaseous species. The influence of temperature-dependent viscosity on retaining fission products, compared to consistent values, is also discussed. The feasibility of integrating CFD with Thermochimica showed promising results, broadening insights into multiphysics systems and setting the stage for its application in more intricate scenarios

    [Carotid endarterectomy with placement of a PUR (polyurethane) patch]

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    In this study, 40 patients who underwent surgery for cerebro-vascular insufficiency were considered. Carotid endarterectomy was the procedure of choice in all of the patients; the arteriotomy was always closed using a PUR patch, a new material that, for its chemical and physical characteristics seems to be a good alternative to PTFE. All of the patients underwent surgery under loco-regional anesthesia, allowing a perioperative monitoring of the neurological status through the patient's active collaboration. During the postoperative period, non local or systemic pathology related to the use of the patch has been observed. During the short and half term follow-up, the patients underwent echo-Doppler of the supra-aortic trunks that didn't show either false aneurysms or thrombosis on the patch surface

    Urinary kallikrein excretion and plasma renin activity in patients with essential hypertension and primary aldosteronism

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    1. The 24 h urinary excretion of kallikrein has been studied in 40 normotensive control subjects and in 74 age-matched patients with essential hypertension under similar conditions. By use of the renin-sodium index, hypertensive patients were divided into two subgroup: low-renin hypertension and normal-renin hypertension patients. Urinary kallikrein determinations were also obtained from six hypertensive patients with primary aldosteronism. 2. Urinary kallikrein was significantly lower both in patients with normal-renin and low-renin essential hypertension. Urinary kallikrein excretion was very high in the patients with primary aldosteronism. 3. In nine hypertensive patients beta-adreno-receptor-blocking therapy caused a significant decrease of plasma renin activity, but had no significant effect on urinary kallikrein excretion. 4. The results support the concept that low urinary kallikrein is likely to be a marker of essential hypertension. Under certain conditions its excretion is positively related to mineralocorticoid hormone concentrations but it is not primarily related to the renin-angiotensin system
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