2,160 research outputs found

    Cross-Border Acquisition or Greenfield Entry: Does it Matter for Affiliate R&D?

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    This paper investigates how the entry mode of foreign direct investment (FDI) affects the affiliate R&D activities using unique data on Swedish multinational firms over a long period of time (1970 to 1998). On average, acquired affiliates are more likely to do R&D and have a higher level of R&D intensity than affiliates created by greenfield entry. This difference in observed R&D is explained by differences in parent, affiliate, industry and country characteristics as well as by different reactions to these characteristics, as predicted by the recent theoretical literature on international mergers and acquisitions (M&As). The results also suggest that M&As are, to a larger extent, motivated by asset-seeking motives than greenfield entry, especially in the 1990s.FDI; M&A; Greenfield Investment; R&D; Multinational Firm

    CATH_Supplemental_text_final_(1) - Development of Multidisciplinary Anticoagulation Management Guidelines for Patients Receiving Durable Mechanical Circulatory Support

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    CATH_Supplemental_text_final_(1) for Development of Multidisciplinary Anticoagulation Management Guidelines for Patients Receiving Durable Mechanical Circulatory Support by Amy A. Levesque, Andrea R. Lewin, Jessica Rimsans, Katelyn W. Sylvester, Lara Coakley, Frank Melanson, Hari Mallidi, Mandeep Mehra, Michael M. Givertz, and Jean M. Connors in Clinical and Applied Thrombosis/Hemostasis</p

    Author Correction: Genetic architecture of host proteins involved in SARS-CoV-2 infection.

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    The original version of this Article cited “Mehra, M. R., Desai, S. S., Kuy, S., Henry, T. D. &amp; Patel, A. N. Cardiovascular disease, drug therapy, and mortality in Covid-19. N. Engl. J. Med. 382, e102 (2020)” as Ref. 20. The cited paper was retracted; accordingly, Ref. 20 has been replaced with "Grasselli G et al. Risk factors associated with mortality among patients with COVID-19 in intensive care units in Lombardy, Italy. JAMA Intern. Med. 180, 1345–1355 (2020)”. This has been corrected in the PDF and HTML versions of the article

    Pinna-related transfer functions and lossless wave equation using finite-difference methods: Validation with measurements

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    Nowadays, wave-based simulations of head-related transfer functions (HRTFs) lack strong justifications to replace HRTF measurements. The main cause is the complex interactions between uncertainties and biases in both simulated and measured HRTFs. This paper deals with the validation of pinna-related high-frequency information in the ipsilateral directions-of-arrival, computed by lossless wave-based simulations with finite-difference models. A simpler yet related problem is given by the pinna-related transfer function (PRTF), which encodes the acoustical effects of only the external ear. Results stress that PRTF measurements are generally highly repeatable but not necessarily easily reproducible, leading to critical issues in terms of reliability for any ground truth condition. On the other hand, PRTF simulations exhibit an increasing uncertainty with frequency and grid-dependent frequency changes, which are here quantified analyzing the benefits in the use of a unique asymptotic solution. In this validation study, the employed finite-difference model accurately and reliably predict the PRTF magnitude mostly within ±1 dB up to ≈8 kHz and a space- and frequency-averaged spectral distortion within about 2 dB up to ≈ 18 kHz

    Loggerhead turtle, Caretta caretta (Linnaeus, 1758) (Testudines, Cheloniidae), as a new host of Monticellius indicum Mehra, 1939 (Digenea: Spirorchiidae) and associated lesiond to spirorchiid eggs

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    The present note describes the occurrence of Monticellius indicum Mehra, 1939 (Digenea: Spirorchiidae) in an adult loggerhead turtle, Caretta caretta (Linnaeus, 1758), found on the coast of the state of Rio de Janeiro, Brazil. Pathological changes due to spirorchiid eggs (type 1 and 3) were found in gastrointestinal system, endocrine system, and heart. This parasite has previously been described in the green turtle, Chelonia mydas (Linnaeus, 1758), from Pakistan, Brazil and Costa Rica as well as in the hawksbill sea turtle, Eretmochelys imbricata (Linnaeus, 1766), in Brazil. This note reports the loggerhead turtle as a new host for M. indicum

    Pinna-related transfer functions and lossless wave equation using finite-difference methods: Verification and asymptotic solution

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    A common approach when employing discrete mathematical models is to assess the reliability and credibility of the computation of interest through a process known as solution verification. Present-day computed head-related transfer functions (HRTFs) seem to lack robust and reliable assessments of the numerical errors embedded in the results which makes validation of wave-based models difficult. This process requires a good understanding of the involved sources of error which are systematically reviewed here. The current work aims to quantify the pinna-related high-frequency computational errors in the context of HRTFs and wave-based simulations with finite-difference models. As a prerequisite for solution verification, code verification assesses the reliability of the proposed implementation. In this paper, known and manufactured formal solutions are used and tailored for the wave equation and frequency-independent boundary conditions inside a rectangular room of uniform acoustic wall-impedance. Asymptotic estimates for pinna acoustics are predicted in the frequency domain based on regression models and a convergence study on sub-millimeter grids. Results show an increasing uncertainty with frequency and a significant frequency-dependent change among computations on different grids

    Sex-specific variation in R-loop formation in Drosophila melanogaster

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    Source Data for manuscript, "Sex-specific variation in R-loop formation in Drosophila melanogaster"
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