153 research outputs found

    The integrated angular bispectrum

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    We study the position-dependent power spectrum and the integrated bispectrum statistic for 2D cosmological fields on the sphere (integrated angular bispectrum). First, we derive a useful, mm-independent, formula for the full-sky integrated angular bispectrum, based on the construction of azimuthally symmetric patches. We then implement a pipeline for integrated angular bispectrum estimation, including a mean-field correction to account for spurious isotropy-breaking effects in realistic conditions (e.g., inhomogenous noise, sky masking). Finally, we show examples of applications of this estimator to CMB analysis, both using simulations and actual Planck data. Such examples include fNLf_\mathrm{NL} estimation, analyses of non-Gaussianity from secondary anisotropies (ISW-lensing and ISW-tSZ-tSZ bispectra) and studies of non-Gaussian signatures from foreground contamination.Comment: 38 pages, 14 figure

    Stress echocardiography in heart failure

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    Abstract Echocardiography has the ability to noninvasively explore hemodynamic variables during pharmacologic or exercise stress test in patients with heart failure. In this review, we detail some important potential applications of stress echocardiography in patients with heart failure. In patients with coronary artery disease and chronic LV dysfunction, dobutamine stress echocardiography is able to distinguish between viable and fibrotic tissue to make adequate clinical decisions. Exercise testing, in combination with echocardiographic monitoring, is a method of obtaining accurate information in the assessment of functional capacity and prognosis. Functional mitral regurgitation is a common finding in patients with dilated and ischaemic cardiomyopathy and stress echocardiography in the form of exercise or pharmacologic protocols can be useful to evaluate the behaviour of mitral regurgitation. It is clinical useful to search the presence of contractile reserve in non ischemic dilated cardiomyopathy such as to screen or monitor the presence of latent myocardial dysfunction in patients who had exposure to cardiotoxic agents. Moreover, in patients with suspected diastolic heart failure and normal systolic function, exercise echocardiography could be able to demonstrate the existence of such dysfunction and determine that it is sufficient to limit exercise tolerance. Finally, in the aortic stenosis dobutamine echocardiography can distinguish severe from non-severe stenosis in patients with low transvalvular gradients and depressed left ventricular function.</p

    CMB constraints on running non-Gaussianity

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    We develop a complete set of tools for CMB forecasting, simulation and estimation of primordial running bispectra, arising from a variety of curvaton and single-field (DBI) models of Inflation. We validate our pipeline using mock CMB running non-Gaussianity realizations and test it on real data by obtaining experimental constraints on the f_NL running spectral index, n_NG, using WMAP 9-year data. Our final bounds (68% C.L.) read −0.6 < n_NG < 1.4, −0.3 < n_NG < 1.2, −1.1 < n_NG < 0.7 for the single-field curvaton, two-field curvaton and DBI scenarios, respectively. We show forecasts and discuss potential improvements on these bounds, using Planck and future CMB surveys
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