1,138 research outputs found
M. Mabrouk.- Les exceptions de procédure devant les juridictions internationales.
No full textM. Mabrouk.- Les exceptions de procédure devant les juridictions internationales.. In: Revue internationale de droit comparé. Vol. 20 N°1, Janvier-mars 1968. p. 236
M. Mabrouk.- Les exceptions de procédure devant les juridictions internationales.
No full textM. Mabrouk.- Les exceptions de procédure devant les juridictions internationales.. In: Revue internationale de droit comparé. Vol. 20 N°1, Janvier-mars 1968. p. 236
ACCUEIL DE MME HALA MABROUK (UNIV. SFAX-AMU)
No full textMme Hala Mabrouk, doctorante en cotutelle de l’Université de Sfax et d’Aix Marseille Université, prépare une thèse intitulée « Iunca, relais commercial dans l’Antiquité » qui a pour ambition d’exploiter la documentation littéraire, épigraphique, archéologique et céramologique permettant d’estimer le rôle de la cité portuaire de Iunca dans le grand commerce méditerranéen, principalement aux époques vandale et byzantine, sous la direction de Sami Ben Tahar, Maître de recherche HDR (INP) et de M..
Cohomology and Deformations of left-symmetric Rinehart Algebras
No full textWe introduce a notion of left-symmetric Rinehart algebras, which is a generalization of a left-symmetric algebras. The left multiplication gives rise to a representation of the corresponding sub-adjacent Lie-Rinehart algebra. We construct left-symmetric Rinehart algebra from O-operators on Lie-Rinehart algebra. We extensively investigate representations of a left-symmetric Rinehart algebras. Moreover, we study deformations of left-symmetric Rinehart algebras, which is controlled by the second cohomology class in the deformation cohomology. We also give the relationships between O-operators and Nijenhuis operators on left-symmetric Rinehart algebras.arXiv admin note: text overlap with arXiv:1710.03749, arXiv:1312.6526, arXiv:1808.01909 by other author
Endometriosis in Monozygotic and Dizygotic Twins: A Review of Literature
No full textEndometriosis is a common estrogen-dependent inflammatory disease and a major contributor to pelvic pain and
subfertility in women of reproductive age. Its etiology and pathogenesis are not well known yet, but different studies
had highlighted its multifactorial nature, influenced by both genetic and environmental components. This minireview
analyzes the prevalence of the disease and the concordance for the presence and stage of endometriosis
in monozygotic (MZ) and dizygotic (DZ) twins. A higher concordance for the presence of the disease in MZ twins
rather than DZ twins was observed, with a statistically significant difference (p-value < 0.05). Only one study had
evaluated the concordance for endometriosis stage within MZ twins, observing a high rate of concordance. Genetic
component seems to play a pivotal role in the development of endometriosis and its severity
Unicornuate uterus with noncommunicating functional horn: diagnostic workup and laparoscopic horn amputation
No full textObjective: To describe the diagnosis and the management of hematometra in a patient with unicornuate uterus with noncommunicating functional horn (hemi uterus and rudimentary uterine hemicavity). Design: Video case report. Setting: Minimally invasive gynaecology unit. Patient(s): Sixteen-year-old nulliparous woman admitted to the gynaecologic emergency department with pelvic pain during menses. Intervention(s): Two-dimensional transvaginal ultrasound, magnetic resonance imaging, and laparoscopic rudimentary horn resection. Main Outcome Measure(s): Description of a case of anomaly of the female reproductive tract treated by laparoscopy. Result(s): After pain reduction and stabilization of clinical condition, ultrasound and magnetic resonance were performed, which detected a hemi uterus with a right rudimentary uterine hemicavity and a hematosalpinx. The removal of the right rudimentary uterine horn was successfully performed. The patient was in good health at the 3-month follow-up visit. Conclusion(s): Laparoscopic amputation of a functional rudimentary horn is considered the basic and traditional surgical option for women with hemiuterus. A detailed diagnostic evaluation should be performed to avoid misdiagnoses of other anomalies with blind hemicavity, which may be treated by hysteroscopy. Laparoscopic surgery with minimally invasive approach could be an essential tool to treat these cases, achieving optimal results with low postsurgical pain and a short hospital stay
High temporal resolution microdialysis reveals cholinergic spikes preceding upshifts in attentional performance.
No full textPrefrontal cholinergic neurotransmission mediates the cognitive control of attention and the detection of cues. Two modes of cholinergic neurotransmission can be separated. Relatively slow or tonic (tens of seconds or minutes) modulate cortical circuitry as a function of the demands on attention (St. Peters et al, 2011). Fast, second-based release events (or transients) are generated via local cortical circuitry and are necessary for the detection of cues (Hasselmo & Sarter 2011). Transients are recorded using amperometry and enzyme-coated microelectrodes. Tonic levels of cholinergic neurotransmission are monitored by microdialysis; importantly this is not a confound of the necessity of long collection intervals but our evidence indicates that tonic levels are not merely representing integrated transients. To further test this hypothesis and to explore the timescale of variations in tonic cholinergic activity in a given behavioral context and to refine the relationships between behavioral/cognitive processes and such variations, we employed a novel HPLC-tandem mass spectrometry (MS) method (Song et al, 2012) to detect acetylcholine (ACh) and several monoamines and amino acids from 3-min collections (1 μL/min; no AChesterase inhibitor added). The focus on 3-min collections was based on our observation that rats performing the sustained attention task (SAT) frequently shift between good and poor levels of performance (defined as SAT scores >0.34 and at chance, or <0.17, respectively). Averaged across SAT sessions, ACh release levels corresponded with those previously obtained from 8-min collections and conventional HPLC-EC methods. However, performance-associated ACh levels fluctuated drastically across 3-min collections, ranging from pre-task baseline levels to 500% above baseline. Cholinergic spikes were observed just prior to shifts from random levels of performance to good levels of performance. Specifically, over 14 animals, 75% of such up-shifts were preceded by increases in cholinergic neurotransmission that were at least 3 SD above baseline levels. These findings indicate the usefulness of high temporal resolution microdialysis. The results are consistent with the hypothesis that tonic cholinergic activity modulates cortical target circuitry as a function of the subjects’ motivation to enhance attentional performance and to orchestrate, the mechanisms designed to enhance signal processing, noise filtering and task compliance (Sarter & Paolone 2011). Tonic cholinergic activity in SAT performing animals is a major target of treatments designed to benefit cognitive performance in ADHD, schizophrenia, PD and other disorders
Endometriosis: Novel models, diagnosis, and treatment
No full textEndometriosis remains a cause of significant morbidity in
reproductive-aged women resulting in pelvic pain, pelvic
masses, and infertility. Endometriosis is defined as the presence
of endometrial glands and stroma outside of their normal
intrauterine location, most commonly in the dependent
portions of the pelvis. Endometriosis is treated with medical
therapies, surgery or both.Themedical therapies include oral
contraceptive pills, progestins, gonadotropin releasing hormone
analogues, and danazol. All of these medical therapies
induce a hormonal steady state that results in an environment
not conducive to the growth of endometriosis. Surgical therapies
for endometriosis-associated pain include the removal
of endometriotic implants and adhesions with restoration
of normal anatomy. Laparoscopy is an effective surgical
approach with the goal of excising visible endometriosis.
Since endometriosis is a chronic condition, it is not uncommon
for recurrences to occur. While endometriosis remains
an enigmatic disease, the introduction of new pharmacologic
agents and newer endoscopic methods of surgical treatment
has facilitated and improved the overall management of this
disease.
This special issue contains some papers that refer to
molecular and cellular mechanisms of endometriosis physiopathology
and some papers that refer to biomarker development
for improved early diagnosis and risk of disease,
while the other papers refer minimally to invasive treatment
for endometriosis and new medical therapies. Finally, there
are somemanuscripts about prevention of endometriosis and
novel models in endometriosis research
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