237 research outputs found
ANALISIS KESUKSESAN PENERAPAN E-COMMERCE NYENYES.COM DENGAN MODEL MOLLA DAN LICKER
No full textPenelitian ini bertujuan untuk mengetahui kesuksesan sistem E-Commere pada
nyenyes menggunakan model Molla dan Licker. Penelitian ini menggunakan
semua variabel yang ada pada model Molla dan Licker. Data dalam penelitian ini
dikumpulkan dengan menggunakan kuesioner yang disebarkan kepada 100
responden. Analisis data yang dilakukan menggunakan analisis deskriptif dan
analisis regresi berganda.. Dari hasil pengujian variabel yang paling besar adalah
variabel Trust terhadap Customer E-Commerce Satisfaction dengan nilai koefisien
regresi sebesar 0,312 (3,12 %). dan yang paling kecil adalah Variabel Support &
Service terhadap pengguna yang berkaitan dengan dukungan dan pelayanan yang
di berikan oleh pihak system E-Commerce baik pada saat menggunakan sistem, saat
bertransaksi maupun saat pengiriman barang sehingga para pengguna dapat
merasakan pelayan dan service yang baik yang di berikan
Cardiac output by model flow method from intra-arterial and finger tip pulse pressure profiles
No full textModelflow®, when applied to non-invasive fingertip pulse pressure recordings, is a poor predictor of cardiac output (Q’ litre· min-1). The use of constants established from the aortic elastic characteristics, which differ from those of finger arteries, may introduce signal distortions, leading to errors in computing Q’. We therefore hypothesized that peripheral recording of pulse pressure profiles undermines the measurement of Q’ withModelflow®, so we compared Modelflow® beat-by-beat Q’ values obtained simultaneously non-invasively from the finger and invasively from the radial artery at rest and during exercise. Seven subjects (age, 24.0 + - 2.9 years; weight, 81.2 + - 12.6 kg) rested, then exercised at 50 and 100 W, carrying a catheter with a pressure head in the left radial artery and the photoplethysmographic cuff of a finger pressure device on the third and fourth fingers of the contralateral hand. Pulse pressure from both devices was recorded simultaneously and stored on a PC for subsequent Q’ computation. The mean values of systolic, diastolic and mean arterial pressure at rest and exercise steady state were significantly (P < 0.05) lower from the finger than the intra-arterial catheter. The corresponding mean steady-state Q’ obtained from the finger (Q’porta) was significantly (P < 0.05) higher than that computed from the intra-arterial recordings (Q’pia). The line relating beat-by-beat Q’porta and Q’pia was y = 1.55x - 3.02 (r2 = 0.640). The bias was 1.44 litre · min-1 and the precision was 2.84 litre · min-1.The slope of this line was significantly higher than 1, implying a systematic overestimate of Q’ by Q’porta with respect to Q’pia. Consistent with the tested hypothesis, these results demonstrate that pulse pressure profiles from the finger provide inaccurate absolute Q’ values with respect to the radial artery, and therefore cannot be used without correction with a calibration factor calculated previously by measuring Q’ with an independent method
The effects of β1-adrenergic blockade on cardiovascular oxygen flow in normoxic and hypoxic humans at exercise
No full textPatients:6 healthy subjects mean age 25.5 years were studied.TypeofStudy:This study determined the effects of selective beta-adrenergic blockade with Lopresor on the oxygen flow in arterial blood (Q̇aO2) and oxygen flow in mixed venous blood (oxygen return, Q̇v̄O2) in humans exercising in normoxia and in acute normobaric hypoxia.DosageDuration:Initially 7.5 mg iv bolus; additional doses up to 30-40 mg until a quasi-complete receptor blockade was achieved.Results:Without Lopresor, PaO2 and PaCO2 were lower in hypoxia than in normoxia. In both hypoxia and normoxia conditions, Lopresor did not induce significant differences in PaO2 and PaCO2 with respect to control condition. Arterialized blood pH was higher in hypoxia than in normoxia and was unaffected by Lopresor. [La]b was higher in hypoxia than in normoxia and was unaffected by Lopresor. The highest [La]b values were observed at 150 W in hypoxia. Without Lopresor the fH, SV, Q̇ and Q̇aO2 increased significantly at exercise in both normoxia and in hypoxia. fH was systematically and significantly higher in hypoxia than in normoxia at each workload. SaO2 and CaO2 were lower in hypoxia than in normoxia. In hypoxia, they also decreased with increasing workload. As a result of this, and despite the lower arterial-venous O2 differences in hypoxia, the O2 extraction coefficient was greater in hypoxia than in normoxia. In normoxia the difference between Q̇aO2 and V̇02 (=Q̇V̄O2) did not change with increasing workload. In hypoxia, Q̇V̄O2 decreased as a function of workload. The resting Q̇v̄O2 value in normoxia was significantly lower than the corresponding invariant values at exercise. In hypoxia the resting Q̇V̄O2 value did not differ significantly from the corresponding value in normoxia. However, the Q̇V̄O2 values at 100 and 150 power (W) in C were significantly lower than the corresponding values in normoxia. With Lopresor, the fH, SV, Q̇, and Q̇aO2 increased significantly during exercised in both normoxia and hypoxia conditions. At rest and at each workload, Lopresor systematically and significantly decreased fH, both in normoxia and in hypoxia. The lower fH at any given V̇O2 implied a significant increase in the oxygen pulse with Lopresor. Q̇ values were found significantly higher at each fH level under Lopresor in hypoxia than in normoxia as a consequence of increased SV. SV values were significantly higher under Lopresor than in control condition in both normoxia and hypoxia. In normoxia, Q̇ was significantly decreased by Lopresor at 100 power (W) exercise and above, and in hypoxia at rest and at 50 W. As in control condition, SaO2 and CaO2 were lower in hypoxia than in normoxia. In hypoxia they also decreased with increasing workload. In both conditions the values observed under Lopresor were not significantly different from those found in control condition. The Q̇v̄O2 decrease as a function of workload in hypoxia paralleled an analogous decrease in SaO2.AdverseEffects:No adverse events were mentionedAuthorsConclusions:The results of the present study are in agreement with the tested hypothesis, as this study showed that selective blockade of beta1-adrenergic receptors decreased Q̇aO2 and Q̇v̄O2 significantly during exercise in normoxia as well as during rest and light exercise in hypoxia.FreeText:Experiments were performed in normoxia and in acute normobaric hypoxia. In both conditions the subjects performed two incremental exercise tests, one without Lopresor and one after having induced quasi-complete beta-adrenergic blockade with Lopresor. Tests: oxygen consumption (V̇O2), carbon dioxide output (V̇CO2), expired ventilation (V̇E), heart rate (fH, electrocardiography), SaO2 (oximetry), hemoglobin (Hb), blood lactate concentration ([La]b), cardiac output (Q̇), stroke volume (SV), arterialized blood carbon dioxide partial pressure (PaCO2), and arterialized blood oxygen partial pressure (PaO2)
Cardiac output by Modelflow® method from intra-arterial and fingertip pulse pressure profiles
No full textModelflow®, when applied to non-invasive fingertip pulse pressure recordings, is a poor predictor of cardiac output (Q˙ , litre · min−1). The use of constants established from the aortic elastic characteristics, which differ from those of finger arteries, may introduce signal distortions, leading to errors in computing Q˙ .We therefore hypothesized that peripheral recording of pulse pressure
profiles undermines the measurement of Q˙ with Modelflow®, so we compared Modelflow® beat-by-beat ˙Q values obtained simultaneously non-invasively from the finger and invasively from the radial artery at rest and during exercise. Seven subjects (age, 24.0+−2.9 years; weight, 81.2+−12.6 kg) rested, then exercised at 50 and 100 W, carrying a catheter with a pressure head in the left radial artery and the photoplethysmographic cuff of a finger pressure device on the third and fourth fingers of the contralateral hand. Pulse pressure from both devices was recorded simultaneously and stored on a PC for subsequent ˙Q computation. The mean values of systolic, diastolic and mean arterial pressure at rest and exercise steady state were significantly (P<0.05) lower from the finger than the intra-arterial catheter. The corresponding mean steady-state ˙Q obtained from the finger (˙Qporta) was significantly (P<0.05) higher than that computed from the intra-arterial recordings (˙Qpia). The line relating beat-by-beat ˙Qporta and ˙Qpia was y=1.55x−3.02 (r2 =0.640). The bias was 1.44 litre · min−1 and the precision was 2.84 litre · min−1. The slope
of this line was significantly higher than 1, implying a systematic overestimate of ˙Q by ˙Qporta with respect to ˙Qpia. Consistent with the tested hypothesis, these results demonstrate that pulse
pressure profiles from the finger provide inaccurate absolute ˙Q values with respect to the radial artery, and therefore cannot be used without correction with a calibration factor calculated previously by measuring ˙Q with an independent method
Infection control capacity building in European countries with limited resources: issues and priorities
No full textWe report the results of a panel investigation aimed at assessing the critical aspects regarding healthcare-associated infections in European countries with limited resources and pinpointing the highest priority issues that need to be addressed for effective infection control. Questionnaires were designed and information collected from national EUNETIPS representatives in Bulgaria, Hungary, Kosovo, Romania, and Serbia. Based on the data collected, we concluded that rigorous implementation of existing law, standardized training, and political commitment constitute a common relevant background and provide the lessons to be learnt for aligning healthcare systems in this area with internationally recommended standards of infection control
Attributing ocean acidification to major carbon producers
No full text© The Author(s), 2019. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Licker, R.; Ekwurzel, B.; Doney, S. C.; Cooley, S. R.; Lima, I. D.; Heede, R.; Frumhoff, P. C. Attributing ocean acidification to major carbon producers. Environmental Research Letters. 14(12), (2019): 124060, doi:10.1088/1748-9326/ab5abc.Recent research has quantified the contributions of CO2 and CH4 emissions traced to the products of major fossil fuel companies and cement manufacturers to global atmospheric CO2, surface temperature, and sea level rise. This work has informed societal considerations of the climate responsibilities of these major industrial carbon producers. Here, we extend this work to historical (1880–2015) and recent (1965–2015) acidification of the world's ocean. Using an energy balance carbon-cycle model, we find that emissions traced to the 88 largest industrial carbon producers from 1880–2015 and 1965–2015 have contributed ~55% and ~51%, respectively, of the historical 1880–2015 decline in surface ocean pH. As ocean acidification is not spatially uniform, we employ a three-dimensional ocean model and identify five marine regions with large declines in surface water pH and aragonite saturation state over similar historical (average 1850–1859 to average 2000–2009) and recent (average 1960–1969 to average of 2000–2009) time periods. We characterize the biological and socioeconomic systems in these regions facing loss and damage from ocean acidification in the context of climate change and other stressors. Such analysis can inform societal consideration of carbon producer responsibility for current and near-term risks of further loss and damage to human communities dependent on marine ecosystems and fisheries vulnerable to ocean acidification.The approach of using equation (1) benefited from discussions with Myles R Allen (University of Oxford) and Inez Fung (University of California, Berkeley). M W Dalton provided insights for the incorporation of the updated carbon producers data. Chloe Ames provided support for references. S Doney acknowledges support from the US National Science Foundation and the University of Virginia Environmental Resilience Institute. R Licker, B Ekwurzel and P C Frumhoff acknowledge the support of the Grantham Foundation for the Protection of the Environment, Wallace Global Fund, and Rockefeller Family Fund to the Union of Concerned Scientists. R Heede gratefully acknowledges the financial support of Wallace Global Fund, Rockefeller Brothers Fund, and Union of Concerned Scientists. We thank two anonymous reviewers for their helpful comments, which greatly improved our manuscript
Influence of fibre openness on processibility of cotton and yarn quality: Part II - Effect of carding parameters
No full text405-410The influence
of fibre openness at carding on processibility of cotton and yarn quality
has been studied. It is observed that the openness at card increases with the decrease
in feed plate to licker-in and cylinder
to flat settings and with the
increase in licker-in speed. A steady increase in card cleaning efficiency is observed with the increase in openness of card web which is due to the fact that the better opening creates more scope for trash to get exposed and released easily from the fibre. Yarn irregularity and tenacity improve with the increase in openness only up to a certain extent and then deteriorate.</span
Extensively drug-resistant Myroides odoratimimus – a case series of urinary tract infections in immunocompromised patients
No full textMonica Licker,1,2 Teodora Sorescu,3,4 Maria Rus,5,6 Natalia Cirlea,6 Florin Horhat,1 Cristiana Jurescu,5,6 Mircea Botoca,7,8 Alin Cumpănas,7,8 Romulus Timar,3,4 Delia Muntean1,2 1Department of Microbiology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania; 2Clinical Laboratory, “Pius Brînzeu” Emergency Clinical County Hospital, Timisoara, Romania; 3Department of Internal Medicine II, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania; 4Diabetes Clinic, “Pius Brînzeu” Emergency Clinical County Hospital, Timisoara, Romania; 5“Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania; 6“Pius Brînzeu” Emergency Clinical County Hospital, Timisoara, Romania; 7Department of Orthopaedics – Traumatology, Urology and Medical Imaging, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania; 8Urology Unit, “Pius Brînzeu” Emergency Clinical County Hospital, Timisoara, Romania Purpose: We report an outbreak of urinary tract infections (UTIs) caused by Myroides odoratimimus, which occurred in the largest clinical hospital in western Romania. Patients and methods: From June to August 2017, four strains of M. odoratimimus were isolated from the urine samples of patients hospitalized in the urology, diabetes, and surgery departments. Hospital records of all patients whose urine cultures were positive for M. ­odoratimimus were reviewed retrospectively. We also reviewed the cases reported in the literature. Results: All UTIs, except one, were hospital-acquired infections. All patients with M. odoratimimus UTIs were immunocompromised. Three patients underwent urinary catheterization with a Foley’s catheter upon admission in the emergency department and one presented for replacement of ureterostomy tubes. All Myroides isolates were resistant to almost all the tested antibiotics. Two patients were successfully treated with tigecycline and one was receiving antimicrobial treatment for another infection at the time of isolation of the microorganism. Conclusion: Although M. odoratimimus is an uncommon pathogen, clinicians should be aware of its ability to cause UTI outbreaks, especially in the immunocompromised population. Due to its multi-drug resistance, it is important to rapidly identify Myroides spp. in order to choose the best treatment regimen. Keywords: Myroides odoratimimus, urinary tract infection, resistance, outbrea
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