65 research outputs found
A genetic structure of the early immigrants (Mukkalathor) of Tamil Nadu as inferred from autosomal loci
No full textGenomic affinity based on eight human - specific polymorphic insertion/ deletion loci was studied in an early immigrant population, Thevar group, of Tamil Nadu, South India. They are traditionally agriculturists, culturally homogenous and endogamous. The seven Alu elements (Alu APO, Alu CD4, Alu PV92, Alu FXIIIB, Alu ACE, Alu PLAT, Alu D1) and one nuclear insertion of mitochondrial DNA segment (mtNUC) were analyzed for all the DNA samples. All these loci showed high levels of polymorphism in caste populations of Tamil Nadu, thereby reflecting their common ancestry. The significant greater inter-individual variation and the moderate population differentiation probably indicate genetic closeness of these populations. The present study populations were also compared with six other caste populations of Tamil Nadu for which the data were available. Phylogenetic analysis of these populations broadly corresponds to their known ethno-historical affinities
A genetic structure of the early immigrants (Mukkalathor) of Tamil Nadu as inferred from autosomal loci
No full textGenomic affinity based on eight human - specific polymorphic insertion/ deletion loci was studied in an early immigrant population, Thevar group, of Tamil Nadu, South India. They are traditionally agriculturists, culturally homogenous and endogamous. The seven Alu elements (Alu APO, Alu CD4, Alu PV92, Alu FXIIIB, Alu ACE, Alu PLAT, Alu D1) and one nuclear insertion of mitochondrial DNA segment (mtNUC) were analyzed for all the DNA samples. All these loci showed high levels of polymorphism in caste populations of Tamil Nadu, thereby reflecting their common ancestry. The significant greater inter-individual variation and the moderate population differentiation probably indicate genetic closeness of these populations. The present study populations were also compared with six other caste populations of Tamil Nadu for which the data were available. Phylogenetic analysis of these populations broadly corresponds to their known ethno-historical affinities
An Enhanced Approach of Genetic and Ant colony based Load Balancing in Cloud Environment
No full textReduced complexity maximum likelihood detection for DAPSK based relay communication systems
No full textEnergy Efficient Constellation Rotation for Multiple-Symbol Differentially Encoded Communications
No full textPerformance analysis of generalized differential modulation using DAPSK for bi-directional relay networks
No full textPerformance analysis of decode and forward cooperative relaying protocol in MIMO Wireless Communication System
No full textA comparison between selenium dioxide and selenium methionine induced cytotoxicity in estrogen receptor negative and positive breast cancer cell lines
No full textSelenium is an essential trace element which has been shown to inhibit the growth of various cancers in numerous studies. Different forms of selenium have been reported to exert variable potencies against the cancer growth. In this study, the effect of selenium dioxide (SeO ) and organic selenium (seleno-L-methionine) 2 on the growth of the human breast cancer cell lines namely MCF-7 (estrogen receptor positive) and MDA-MB-231 (estrogen receptor negative) were compared. The standard MTT (3-4,5-Dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide) assay was used to quantitate the viable cancer cells. Selenium dioxide inhibited cell growth at high concentrations (10G M to 10G M) but showed mild (not significant) stimulation of cell 4 3 proliferation at lower concentration (10G to 10G M). However, selenomethionine exhibited biphasic effects 12 5 on both cell lines. It inhibited cell growth at high concentrations (10G M to 10G M in MCF-7; 10G M in MDA-4 3 3 MB-231) but stimulated cell proliferation at lower concentrations. The findings in this study indicated that selenium dioxide was more potent than selenomethionine in inhibiting both cancer cell lines. Besides, both forms of selenium were also found to be less effective against MDA-MB-231
Effect of the mannose-binding Artocarpus integer lectin on the cellular proliferation of murine lymphocytes
No full textThe effect of the mannose-binding champedak (Artocarpus integer) lectin-M on the cellular proliferation of murine lymphocytes was investigated in this study. Our data demonstrated that the lectin was the main mitogenic component in the crude extract of the champedak seeds. It stimulated the proliferation of murine T cells at an optimal concentration of 2.5 mu g/ml in a 3 day culture. Lectin-M appeared to be a T-cell mitogen as it does not induce significant DNA synthesis when cultured with spleen cells from the nude mouse. In the absence of T cells, the lectin was incapable of inducing resting B cells to differentiate into immunoglobulin secreting plasma cells
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