4,967 research outputs found
Colourings of (k-r,k)-trees
Get PDFTrees are generalized to a special kind of higher dimensional complexes known as -trees ([L. W. Beineke, R. E. Pippert, On the structure of -trees, Proc. 8th S-E Conf. Combinatorics, Graph Theory and Computing, 1977, 75-80]), and which are a natural extension of -trees for . The aim of this paper is to study-trees ([H. P. Patil, Studies on -trees and some related topics, PhD Thesis, University of Warsaw, Poland, 1984]), which are a generalization of -trees (or usual trees when ). We obtain the chromatic polynomial of -trees and show that any two -trees of the same order are chromatically equivalent. However, if in any -tree , then it is shown that there exists another chromatically equivalent graph , which is not a -tree. Further, the vertex-partition number and generalized total colourings of -trees are obtained. We formulate a conjecture about the chromatic index of -trees, and verify this conjecture in a number of cases. Finally, we obtain a result of [M. Borowiecki, W. Chojnacki, Chromatic index of -trees, Discuss. Math. 9 (1988), 55-58] as a corollary in which -trees of Class 2 are characterized
Supplemental Material, jmr.16.0299_web_appendices - Multichannel Strategies for Managing the Profitability of Business-to-Business Customers
No full textSupplemental Material, jmr.16.0299_web_appendices for Multichannel Strategies for Managing the Profitability of Business-to-Business Customers by Justin M. Lawrence, Andrew T. Crecelius, Lisa K. Scheer, and Ashutosh Patil in Journal of Marketing Research</p
A new metabolic model of Drosophila melanogaster and the integrative analysis of Parkinson’s disease
No full textHigh conservation of the disease-associated genes between flies and humans facilitates the common use of Drosophila melanogaster to study metabolic disorders under controlled laboratory conditions. However, metabolic modeling studies are highly limited for this organism. We here report a comprehensively curated genome-scale metabolic network model of Drosophila using an orthology-based approach. The gene coverage and metabolic information of the draft model derived from a reference human model were expanded via Drosophila-specific KEGG and MetaCyc databases, with several curation steps to avoid metabolic redundancy and stoichiometric inconsistency. Furthermore, we performed literature-based curations to improve gene–reaction associations, subcellular metabolite locations, and various metabolic pathways. The performance of the resulting Drosophila model (8,230 reactions, 6,990 metabolites, and 2,388 genes), iDrosophila1 (https://github.com/SysBioGTU/iDrosophila), was assessed using flux balance analysis in comparison with the other currently available fly models leading to superior or comparable results. We also evaluated the transcriptome-based prediction capacity of iDrosophila1, where differential metabolic pathways during Parkinson’s disease could be successfully elucidated. Overall, iDrosophila1 is promising to investigate system-level metabolic alterations in response to genetic and environmental perturbations
A comparison of repetitive corrugation and straightening and high-pressure torsion using an Al-Mg-Sc alloy
Get PDFA comparative study was conducted to evaluate the influence of two different severe plastic deformation (SPD) processes: repetitive corrugation and straightening (RCS) and high-pressure torsion (HPT). Samples of an Al-3Mg-0.25Sc alloy with an initial grain size of ?150 ?m were processed by RCS through 8 passes at room temperature either without any rotation during processing or with a rotation of 90° around the longitudinal axis between each pass. Thin discs of the alloy were also processed for up to 5 turns by HPT at room temperature. The results show that both procedures introduce significant grain refinement with average grain sizes of ?0.6–0.7 ?m after RCS and ?95 nm after HPT. Measurements of the Vickers microhardness gave values of ?128 after RCS and ?156 after HPT. The results demonstrate that processing by HPT is the optimum processing technique in achieving both high strength and microstructural homogeneity
Sustainable Intensification of Rainfed Agriculture through Natural Resource Management: Proceedings of Tata-ICRISAT-ICAR and Model Watershed Projects’Review and Planning Meeting
Get PDFFluidization Characteristics of Sand and Chopped Switchgrass-Sand Mixtures
Get PDFRosana G. Moreira, Editor-in-Chief; Texas A&M UniversityThis is a paper from International Commission of Agricultural Engineering (CIGR, Commission Internationale du Genie Rural) E-Journal Volume 7 (2005): Fluidization Characteristics of Sand and Chopped Switchgrass-Sand Mixtures by K. N. Patil, T. J. Bowser, D. D. Bellmer, R. L. Huhnk
An exPADItion for citrullination in the developing hair follicle
No full textDuring epidermal development, to assure proper tissue structure, highly complex transcriptional networks interact within the stem cell compartments of the epidermis and hair follicles (HFs) to balance the choice between self-renewal or differentiation. The full characterisation of the protein profiles resulting from those transcriptional networks, within the compartments of the HF, remains, however, incomplete. Moreover, the proteins themselves can be regulated via posttranslational modification (PTMs). One such PTM is citrullination, carried out by the peptidylarginine deiminase (PADI) family of enzymes. Although, PADIs have been described in other stem and progenitor cells, their role in hair follicle stem cell (HFSC) and progenitor lineages have remained elusive.The main objectives of this thesis are to address the functional consequences of PADI expression in HFSCs during development.Paper I identifies Padi4 expression in the developing HF, where it is found to participate in restricting proliferation and lineage commitment of HF progenitors, as well as playing a role in the central mechanism for translational control, and by doing so altering the distinct sequential events that mark HF differentiation progression. As a result, we identify citrullination as a means to assert regulation of protein function in HFSCs and progenitors.Paper II identifies alternative isoforms of PADI2 and PADI3, in oligodendrocytes and HF differentiated cells, respectively, and show that the alternative isoforms have an incumbering effect on the enzymatic activity and stability of their conventional counterparts.Paper III is a review paper in which meta-analysis of published human citrullinomes in health and inflammatory disease reveals that citrullination is a commonplace yet highly dynamic molecular regulator of protein function. A strong case is made for the involvement of PADIs and citrullination in hair follicle stem cell biology and inflammatory alopecia.Paper IV addresses the involvement of transcription factor ID1 in self-renewal and differentiation of epidermal progenitor cells during development. This study describes how ID1 facilitates synchronisation of progenitor proliferation and differentiation via TCF3- binding, and establishes a novel axis of coordination for how BMP-induction of Id1 expression via pSMAD1/5 is supressed by CEBPa.The combined efforts within this thesis demonstrate the clear and overarching importance of PADIs and citrullination in skin developmental physiology.List of scientific papersI. Vikhe Patil, K., Genander, M. PADI4 restricts proliferation of hair follicle progenitor cells by rewiring translation. [Manuscript]II. Vikhe Patil, K., Meijer, M., Mak, K. H. M., Yang, W., Falcão A. M., Castelo-Branco, G., Genander, M. Co-expression of PADI isoforms during progenitor differentiation enables functional diversity. Philosophical Transactions B. 2023. [Accepted] https://doi.org/10.1098/rstb.2022.0451 III. Vikhe Patil, K., Mak, K. H. M., Genander, M. A Hairy Cituation – PADIs in Regeneration and Alopecia. Front Cell Dev Biol. (2021) 9, 789676. https://doi.org/10.3389/fcell.2021.789676 IV. Kantzer, C. G*., Yang, W*., Grommisch, D., Vikhe Patil, K., Mak, K. H. M., Shirokova, V., & Genander, M. ID1 and CEBPA coordinate epidermal progenitor cell differentiation. Development. (2022) 149(22), dev201262. *These authors contributed equally to this work. https://doi.org/10.1242/dev.201262 </p
FIGURE 7 in Check-list of Pteridophytes from Gujarat State, Western India
No full textFIGURE 7. Bar graph showing region wise distribution of species of lycophytes and ferns.Published as part of Rajput, Kishore S., Kachhiyapatel, Ronak N., Patil, Sachin M., Vasava, Ajit M., Patel, Ravi S., Patel, Suresh K. & Raole, Vinay M., 2021, Check-list of Pteridophytes from Gujarat State, Western India, pp. 89-104 in Phytotaxa 514 (2) on page 100, DOI: 10.11646/phytotaxa.514.2.1, http://zenodo.org/record/531563
Journal of Public Procurement : Volume 11 Number 4 Winter 2011
No full textRisks Associated with Performance Specifications in Highway Infrastructure Procurement S. S. Patil and K. R. Molenaar Matching Supply-Side Costs with Demand-Side Value in Procurement Auctions J. Chen Services Supply Chain in the United States Navy: An Empirical Study of Current Management Practices A. Apte, U. M. Apte and R. G. Rendon562 hlm.; 23 cm
FIGURE 3. A in Check-list of Pteridophytes from Gujarat State, Western India
No full textFIGURE 3. A Aleurtitopteris anceps (Blanf.) Panigrahi (C.B. Clarke) Ching. B Cheilanthes tenuifolia (Burm. f.) Sw. C and D Athyrium falcatum Bedd. E and F Athyrium parasnathense (C.B.Clarke) Ching ex Mehra & Bir G Thelypteris dentata (Forssk.) E.P. St. John H Hypodematium crenatum subsp. crenatum I Tectaria coadunata (J. Sm.) C. Chr. J Lepisorus nudus (Hook.) Ching K Microsorum membranaceum (D. Don) Ching. Scale Bar: 2 cm (A-C, H, J); 5 cm (D, I, K); 4 cm (E); 3 cm (F); 10 cm (G).Published as part of Rajput, Kishore S., Kachhiyapatel, Ronak N., Patil, Sachin M., Vasava, Ajit M., Patel, Ravi S., Patel, Suresh K. & Raole, Vinay M., 2021, Check-list of Pteridophytes from Gujarat State, Western India, pp. 89-104 in Phytotaxa 514 (2) on page 98, DOI: 10.11646/phytotaxa.514.2.1, http://zenodo.org/record/531563
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