218 research outputs found
Trauma and Self in the Soviet Context: Remarks on Gulag Writings
The present paper is a first reflection on the ideal approaches to study the corpus of lagernaia memuaristika. The author proposes the novel concept of ‘Soviet repression literature’ as a new key concept to study the whole corpus of literature related to Soviet repression under a genre perspective. In this context, the author stretches the peculiarities of Gulag memoirs in relation to the corpus of Soviet repression literature, and underlines how trauma studies and autobiographical studies might help assessing the corpus
Guerra e memoria nella Russia di Putin
The contribution analyses the ways in which the ongoing memory war on the Gulag, which is being fought in Russia between state agencies and NGOs, has played an important role both in the ways the state has organised its repressive machine, and in the way it has used the memory of the Gulag in its nationalistic-oriented narration of past events and identity building
CO metabolism, sensing, and signaling. * di Masi A. and Gullotta F. contributed equally to this work.
CO is a colorless and odorless gas produced by the incomplete combustion of hydrocarbons, both of natural and anthropogenic origin. Several microorganisms, including aerobic and anaerobic bacteria and anaerobic archaea, use exogenous CO as a source of carbon and energy for growth. On the other hand, eukaryotic organisms use endogenous CO, produced during heme degradation, as a neurotransmitter and as a signal molecule. CO sensors act as signal transducers by coupling a "regulatory" heme-binding domain to a "functional" signal transmitter. Although high CO concentrations inhibit generally heme-protein actions, low CO levels can influence several signaling pathways, including those regulated by soluble guanylate cyclase and/or mitogen-activated protein kinases. This review summarizes recent insights into CO metabolism, sensing, and signaling
Introduzione. L’importanza di comprendere. Perché accadrà di nuovo.
This foreword explains the reasons why the volume is necessary to understand the origins of Putin's regime and have a clearer understanding of the full scale invasion of Ukraine perpetrated by the Russian army in February 202
L'Europa e il gulag, il gulag e l'Europa
The article is devoted the the importance of the idea of Europe in Gulag cultur
Intelligencija 2.0. Il web e la tvorčeskaja intelligencija
The debate on intelligentsia in contemporary Russia keeps on being fed by publications about its function and role. After a review of this debate, this article focuses on a specific aspect, i.e. the use of the web by contemporary intelligenty. Some case studies are here analysed with the aim of showing how, while in some situation the social media, and specifically Facebook, is used mainly as an extension or a ‘megaphone’ of someone’s intellectual activity, in others it is a peculiar space for creativity, other than functioning sometimes as one of the grounds where the eternal battle between the power and the intelligentsia is being fought
O2-mediated oxidation of ferrous nitrosylated human serum heme-albumin is limited by nitrogen monoxide dissociation.
Human serum heme-albumin (HSA-heme-Fe) displays globin-like properties. Here, kinetics of O(2)-mediated oxidation of ferrous nitrosylated HSA-heme-Fe (HSA-heme-Fe(II)-NO) is reported. Values of the first-order rate constants for O(2)-mediated oxidation of HSA-heme-Fe(II)-NO (i.e., for ferric HSA-heme-Fe formation) and for NO dissociation from HSA-heme-Fe(II)-NO (i.e., for NO replacement by CO) are k=9.8 × 10(-5) and 8.3 × 10(-4) s(-1), and h=1.3 × 10(-4) and 8.5 × 10(-4) s(-1), in the absence and presence of rifampicin, respectively, at pH=7.0 and T=20.0 °C. The coincidence of values of k and h indicates that NO dissociation represents the rate limiting step of O(2)-mediated oxidation of HSA-heme-Fe(II)-NO. Mixing HSA-heme-Fe(II)-NO with O(2) does not lead to the formation of the transient adduct(s), but leads to the final ferric HSA-heme-Fe derivative. These results reflect the fast O(2)-mediated oxidation of ferrous HSA-heme-Fe and highlight the role of drugs in modulating allosterically the heme-Fe-atom reactivity
O2-mediated oxidation of ferrous nitrosylated human serum heme-albumin is limited by nitrogen monoxide dissociation
Drug binding to Sudlow's site I impairs allosterically human serum heme-albumin-catalyzed peroxynitrite detoxification
- …
