965 research outputs found
Jacques Ryckmans, Walter W. Müller, Yusuf M. Abdallah, Textes du Yémen antique inscrits sur bois (with an English Summary). Avant-Propos de Jean-François Breton. Publications de l’Institut orientaliste de Louvain, 43, Louvain-la-Neuve, 1994
No full textGajda Iwona. Jacques Ryckmans, Walter W. Müller, Yusuf M. Abdallah, Textes du Yémen antique inscrits sur bois (with an English Summary). Avant-Propos de Jean-François Breton. Publications de l’Institut orientaliste de Louvain, 43, Louvain-la-Neuve, 1994. In: Bulletin critique des annales islamologiques, n°12, 1996. pp. 236-239
Effect of curcumin on atherosclerosis in apoE/LDLR - Double knockout mice
No full textIt is widely appreciated that inflammation and oxidant stress contribute to 99 atherogenesis. Curcumin, a polyphenolic natural compound has been reported to possess anti-inflammatory and anti-oxidant actions. We hypothesized that curcumin could inhibit the development of atherosclerosis in the apoE/LDLR - double knockout mice fed with Western diet (21% fat, 0.15% cholesterol w/w, without cholic acid). Curcumin (purity >= 98%), premixed with diet, was given for 4 months 14 at a dose of 0.3 mg/per day/per mouse. In this model curcumin inhibited atherogenesis, measured both by "en face" method (25,15 +/- 2,9% vs. 19,2 +/- 0,6%, p < 0,05) and "cross-section" method (565867 +/- 39764 mu m(2) vs. 299201 +/- 20373 mu m(2), p < 0,05). Importantly, curcumin influenced neither the concentrations of cholesterol and triglycerides in blood nor animal body weight. To our knowledge, this is the first report that shows the anti-atherogenic effect of low dose of curcumin in fine model of atherosclerosis: gene-targeted apoE/LDLR - double knockout mice
Inhibition of nuclear factor-kappa B attenuates atherosclerosis in apoE/LDLR - Double knockout mice
No full textNuclear factor - kappa B (NF-kappa B) is a good therapeutic target for cardiovascular disease and numerous efforts are being made to develop safe NF-kappa B inhibitors. Nowadays many authors address NF-kappa B as a major therapeutic target in atherosclerosis, especially for preventive measures, in the light of two main hypothesis of atherosclerosis: oxidation and inflammation. We hypothesized that ammonium pyrrolidinedithioocarbamate (PDTC) - a well-known inhibitor of NF-kappa B could inhibit the development of atherosclerosis in this experimental model. We used apoE/LDLR - DKO mouse model, which is considered as a one of the best models to study the anti-atherosclerotic effect of drugs. In this model PDTC inhibited atherogenesis, measured both by "en face" method (25,15 +/- 2,9% vs. 15,6 +/- 3 0,6%) and "cross-section" method (565867 +/- 39764 mu m(2) vs. 291695 +/- 30384 mu m(2)). Moreover, PDTC did not change the profile of cholesterol and triglycerides in blood. To our knowledge, this is the first report that shows the effect of PDTC on atherogenesis in gene-targeted apoE/LDLR - double knockout mice
Effect of curcumin on atherosclerosis in apoE/LDLR - Double knockout mice
No full textIt is widely appreciated that inflammation and oxidant stress contribute to 99 atherogenesis. Curcumin, a polyphenolic natural compound has been reported to possess anti-inflammatory and anti-oxidant actions. We hypothesized that curcumin could inhibit the development of atherosclerosis in the apoE/LDLR - double knockout mice fed with Western diet (21% fat, 0.15% cholesterol w/w, without cholic acid). Curcumin (purity >= 98%), premixed with diet, was given for 4 months 14 at a dose of 0.3 mg/per day/per mouse. In this model curcumin inhibited atherogenesis, measured both by "en face" method (25,15 +/- 2,9% vs. 19,2 +/- 0,6%, p < 0,05) and "cross-section" method (565867 +/- 39764 mu m(2) vs. 299201 +/- 20373 mu m(2), p < 0,05). Importantly, curcumin influenced neither the concentrations of cholesterol and triglycerides in blood nor animal body weight. To our knowledge, this is the first report that shows the anti-atherogenic effect of low dose of curcumin in fine model of atherosclerosis: gene-targeted apoE/LDLR - double knockout mice
Inhibition of nuclear factor-kappa B attenuates atherosclerosis in apoE/LDLR - Double knockout mice
No full textNuclear factor - kappa B (NF-kappa B) is a good therapeutic target for cardiovascular disease and numerous efforts are being made to develop safe NF-kappa B inhibitors. Nowadays many authors address NF-kappa B as a major therapeutic target in atherosclerosis, especially for preventive measures, in the light of two main hypothesis of atherosclerosis: oxidation and inflammation. We hypothesized that ammonium pyrrolidinedithioocarbamate (PDTC) - a well-known inhibitor of NF-kappa B could inhibit the development of atherosclerosis in this experimental model. We used apoE/LDLR - DKO mouse model, which is considered as a one of the best models to study the anti-atherosclerotic effect of drugs. In this model PDTC inhibited atherogenesis, measured both by "en face" method (25,15 +/- 2,9% vs. 15,6 +/- 3 0,6%) and "cross-section" method (565867 +/- 39764 mu m(2) vs. 291695 +/- 30384 mu m(2)). Moreover, PDTC did not change the profile of cholesterol and triglycerides in blood. To our knowledge, this is the first report that shows the effect of PDTC on atherogenesis in gene-targeted apoE/LDLR - double knockout mice
Long Term Feasibility Study of In-field Floating Microbial Fuel Cells for Monitoring Anoxic Wastewater and Energy Harvesting
No full text© Copyright © 2019 Cristiani, Gajda, Greenman, Pizza, Bonelli and Ieropoulos. In the present work different prototypes of floating MFCs have been tested in anoxic water environments of wastewater plants in Italy, over a period of 3 years. Several configurations of horizontal (flat) and vertical (tubular) MFCs were assembled, using low-cost and light-weight materials, such as plastic lunch boxes, polystyrene or wood to keep the systems afloat, and ceramics for the MFCs. Untreated carbon cloth or veil was used for both anode and cathode electrodes. Felt (flat MFCs) or clay (tubular MFCs) was used as the cation-exchange separator. Single flat MFCs generated power up to 12 mW/m2 while a 32 cylindrical MFC stack generated up to 18 mW/m2. The testing lasted for more than 2 years and there was no inoculation other than exposing the MFCs to the denitrification environment. The cathodes of the flat MFCs were spontaneously colonized by algae and plants, and this did not affect the stability of the systems. Natural light increased the power output of the flat MFCs which were smaller than 50 × 50 cm. Diurnal oscillation of temperature and periodic water flow did not significantly affect the performance of the MFCs. The largest flat MFC produced the highest absolute power, although in a disrupted way. A new, simple low-energy remote monitoring system, based on LoRa technology was used for data transmission over distances of >500 m. This is a piece of hardware that could potentially be suitable for remote monitoring as part of a network, as it can be directly powered by the deployed MFCs
Microbial fuel cell stack performance enhancement through carbon veil anode modification with activated carbon powder
No full textThe chemical energy contained in urine can be efficiently extracted into direct electricity by Microbial Fuel Cell stacks to reach usable power levels for practical implementation and a decentralised power source in remote locations. Herein, a novel type of the anode electrode was developed using powdered activated carbon (PAC) applied onto the carbon fibre scaffold in the ceramic MFC stack to achieve superior electrochemical performance during 500 days of operation. The stack equipped with modified anodes (MF-CV) produced up to 37.9 mW (21.1 W m−3) in comparison to the control (CV) that reached 21.4 mW (11.9 W m−3) showing 77% increase in power production. The novel combination of highly porous activated carbon particles applied onto the conductive network of carbon fibres promoted simultaneously electrocatalytic activity and increased surface area, resulting in excellent power output from the MFC stack as well as higher treatment rate. Considering the low cost and simplicity of the material preparation, as well as the outstanding electrochemical activity during long term operation, the resulting modification provides a promising anode electrocatalyst for high-performance MFC stacks to enhance urine and waste treatment for the purpose of future scale-up and technology implementation as an applied off-grid energy source
An optimization approach for a complex real-life container loading problem
No full textWe consider a real-world packing problem faced by a logistics company that loads and ships hundreds of trucks every day. For each shipment, the cargo has to be selected from a set of heterogeneous boxes. The goal of the resulting container loading problem (CLP) is to maximize the value of the cargo while satisfying a number of practical constraints to ensure safety and facilitate cargo handling, including customer priorities, load balancing, cargo stability, stacking constraints, positioning constraints, and limiting the number of unnecessary cargo move operations during multi-shipment deliveries. Although some of these constraints have been considered in the literature, this is the first time a problem tackles all of them jointly on real instances. Moreover, differently from the literature, we treat the unnecessary move operations as soft constraints and analyze their trade-off with the value maximization. As a result, the problem is inherently multi-objective and extremely challenging. We tackle it by proposing a randomized constructive heuristic that iteratively combines items in a preprocessing procedure, sorts them based on multiple criteria, uses randomization to partially perturb the sorting, and finally constructs the packing while complying with all the side constraints. We also propose dual bounds based on CLP relaxations. On large-scale industry instances, our algorithm runs in a few seconds and outperforms (in terms of value and constraints handling) both the solutions constructed manually by the company and those provided by a commercial software. The algorithm is currently used by the company generating significant economic and CO2 savings
Involvement of gap junctions in epileptogenesis and manifestation of seizures of the immature and adult neocortex
No full textThe Sarmatian Review, Vol. 18, No. 2
No full textContents: "SR INDEX"; "SR interviews Jan Komski"; Abraham Peck, "Poles and Jews"; Ewa M. Thompson, "Reflections on Richard Lukas' 'The Forgotten Holocaust'"; Michael Wyschogrod, "Reflections on Eva Hoffman's 'Shtetl'"; "BOOKS"; Patrycja A. Gajda, "Polish Americans and Their History (review)"; Michael Winkler, "The Polish Coal Miners' Union and the German Labor Movement in the Ruhr, 1902-1934 (review)"; "SR Translations of Documents: A Letter from Folks-Sztyme and Deportations from Lithuania"; "LETTERS"; "About the Authors
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