72 research outputs found
<i>M. tuberculosis</i> characteristic cording in MODS plate at ×400 magnification with inverted microscope.
No full text<p><i>M. tuberculosis</i> characteristic cording in MODS plate at ×400 magnification with inverted microscope.</p
First report of Salmonella enterica serotype Paratyphi A azithromycin resistance leading to treatment failure
No full textThe prevalence of Salmonella enterica serotype Paratyphi A infection is increasing, and multidrug resistance is a well-recognized problem. Resistance to fluoroquinolones is common and leads to more frequent use of newer agents like azithromycin. We report the first case of azithromycin resistance and treatment failure in a patient with S. Paratyphi A infection
The innate immune response to Mycobacterium tuberculosis is dependent on strain lineage and on host population
No full textIncludes abstract.Includes bibliographical references.The genome structure of Mycobacterium tuberculosis is strongly clonal, in the absence of horizontal gene transfer. Thus it is feasible that clonal lineages may exhibit particular phenotypic characteristics, which may, in turn, result in differences in virulence or influence their association with particular host populations. Indeed, the global distribution of M. tuberculosis strains is not uniform and certain strain lineages predominate in particular geographical areas. Further, there is evidence that some strain lineages are emerging, suggesting differences in virulence. Firstly, we investigated the association between strain genotype of M. tuberculosis and in vitro correlates of virulence such as growth phenotype and cytokine induction in the monocyte-derived macrophage (MDM) model
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