1,721,104 research outputs found
Matematica per le scienze della vita - seconda edizione
No full textManuale innovativo di matematica di base per studenti di scienze della vit
Natural variation in the potency and binding sites of mitochondrial quinone-like inhibitors
No full textA. Avanzini et M. Degli Esposti (éds), Husn Salut and the Iron Age of South East Arabia (2018)
No full textRohmer Jérôme. A. Avanzini et M. Degli Esposti (éds), Husn Salut and the Iron Age of South East Arabia (2018). In: Topoi, volume 22/2, 2018. pp. 709-714
Who wrote Basil's Epistula 38? A Possible Answer through Quantitative Analysis
No full textThe aim of the present paper is to investigate the authorship of Epistula 38 (a work transmitted in Basil's epistolary corpus but also attributed to Gregory of Nyssa) by utilizing statistical methods and numerical computations
Multiple optimal solutions in the portfolio selection model with short-selling
No full textIn this paper an extension of the Lintner model [1] is considered: the problem of portfolio optimization is studied when short-selling is allowed through the mechanism of margin requirements. This induces a non-linear constraint on the wealth. When interest on deposited margin is present, Lintner ingeniously solved the problem by recovering the unique optimal solution of the linear model (no margin requirements). In this paper an alternative and more realistic approach is explored: the nonlinear constraint is maintained but no interest is perceived on the money deposited against short-selling. This leads to a fully non-linear problem which admits multiple and unstable solutions very different among themselves but corresponding to similar risk levels. Our analysis is built on a seminal idea by Galluccio, Bouchaud and Potters [3], who have re-stated the problem of finding solutions of the portfolio optimization problem in futures markets in terms of a spin glass problem. In order to get the best portfolio (i.e. the one lying on the efficiency frontier), we have to implement a two-step procedure. A worked example with real data is presented
Lipid exchange in mitochondrial cytochrome c release: pro-apoptotic effect of maize lipid transfer protein
Full text linkMembrane lipids and protein-lipid interactions are attracting increasing interest in the field of cell death and apoptosis. Some pro-apoptotic proteins, like Bid, appear to have an intrinsic capacity of binding and exchange lipids but it is still unclear whether this function could be relevant for apoptotic signalling cascade. We have studied the ability of a plant lipid transfer protein, not related to animal apoptotic cascade, to induce cytochrome c release from mammalian mitochondria. Non -specific lipid transfer proteins (nsLTPs) are ubiquitous plant proteins that have been shown to bind, in vitro, various amphiphilic molecules including lysolipids and glycolipids and to facilitate in vitro transfer of phospholipids between membranes. The results showed that, in the presence of specific lipid molecules (i.e. lysolipids), ns-LTP from maize is able to induce cytochrome c release from the intermembrane space of mouse liver mitochondria. These data are discussed with respect to the role played by lipids and lipid binding in apoptosis
Relative entropy via non-sequential recursive pair substitution
No full textThe entropy of an ergodic source is the limit of properly rescaled oneblock
entropies of sources obtained applying successive non-sequential recursive
pair substitutions (NSRPS). In this paper we prove that the cross-entropy and
the Kullback–Leibler divergence can be obtained in a similar way
Energy landscape statistics of the random orthogonal model
No full textThe random orthogonal model (ROM) of Marinari-Parisi-Ritort [13, 14] is a model of statistical mechanics where the couplings among the spins are defined by a matrix chosen randomly within the orthogonal ensemble. It reproduces the most relevant properties of the Parisi solution of the Sherrington-Kirkpatrick model. Here we compute the energy distribution, and work out an estimate for the two-point correlation function. Moreover, we show an exponential increase with the system size of the number of metastable states also for non-zero magnetic field
Deterministic spin models with a glassy phase transition
No full textWe consider the infinite-range deterministic spin models with Hamiltonian H = ni,j=1 Ji,j i j , where J is the quantization of a chaotic map of the torus. The mean-field Thouless - Anderson - Palmer (TAP) equations are derived by summing the high-temperature expansion. They predict a glassy phase transition at the critical temperature T near 0.8
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