221 research outputs found
OBSERVATIONAL CONSTRAINTS OF THE INTERACTION BETWEEN PLANETS AND PROTOPLANETARY DISKS
No full textOver the course of almost three decades, exoplanet research has unveiled thousands of planets orbiting stars beyond our Sun. Surprisingly, the majority of these exoplanetary systems exhibit significant differences from our own Solar System. To comprehend the reasons behind these distinctions, it is imperative to study how planets form. Planets take shape during the star formation process, emerging from the material within the protoplanetary disk surrounding the young protostar. Interactions between these newly formed planets and the disk create observable effects on the disk itself, which can be detected in the sub-millimeter to centimeter wavelength range through advanced interferometers like ALMA and VLA.
In this Thesis, I explore various protoplanetary disks, each possessing unique characteristics. They range from extended disks with noticeable substructures in dust emission to a disk surrounding a very low-mass star that may have undergone giant planet formation, as well as a compact, structureless disk exhibiting a peculiar behavior whose origin remains uncertain. The methodologies employed in these investigations are diverse, encompassing high-resolution ALMA observations, comprehensive numerical modeling involving hydrodynamical and radiative transfer simulations, and a multiwavelength analysis spanning from centimeter to sub-millimeter wavelengths, incorporating data from VLA, ALMA, and other interferometers. In all the systems under examination, the presence of planets could potentially play a role, whether giant planets shaping observed dust substructures at tens or hundreds of astronomical units or inner planets generating unresolved substructures, preventing radial drift and leading to the formation of a compact disk
Sphenopalatine endoscopic ganglion block : a revision of a traditional technique for cluster headache
No full textThe diagnosis of chronic cluster headache (CH), the most painful form of headache, is based on typical clinical features characterized by strictly unilateral pain with no side shift and ipsilateral oculofacial autonomic phenomena. The attacks occur several times a day for periods of 1 to 2 months in the episodic form of the disease or less frequently on a daily basis in the chronic form. The pathogenesis of CH involves the activation of parasympathetic nerve structures located within the sphenopalatine ganglion (SPG), which explains many of the associated symptoms, whereas the activation of the ipsilateral hypothalamic gray matter may explain its typical circadian and circannual periodicity. A number of surgical approaches have been tried in cases of chronic CH resistant to pharmacologic therapy, of which SPG blockade has been shown to have certain efficacy. We have adopted a new technique based on endoscopic ganglion blockade that approaches the pterigo-palatine fossa by way of the lateral nasal wall and consists of the injection of a mixture of local anesthetics and corticosteroids, which was performed in 20 selected patients with chronic CH, according to the International Headache Society criteria (18 male, 2 female; mean age 40 yr), who were selected for SPG blockade because they were totally drug resistant. The symptoms improved significantly, but always only temporarily, in 11 cases. These results should be considered rather good because, unlike other frequently used techniques, SPG blockade is not invasive and should therefore always be attempted before submitting patients to more invasive surgical approaches
Deep brain stimulation and cluster headache
No full textIn recent years, neuroimaging data have greatly improved the knowledge on trigeminal autonomic cephalalgias' (TACs) central mechanisms. Positron emission tomography studies have shown that the posterior inferior hypothalamic grey matter is activated during cluster headache attacks as well as in short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT). Voxel-based morphometric MRI has also documented alteration in the same area in cluster headache patients. These data suggest that the cluster headache generator is located in this region and leads us to hypothesise that stimulation of this brain area could relieve intractable cluster headache just as deep brain stimulation improves intractable movements disorders. This view received support by the observation that high frequency stimulation of the ipsilateral hypothalamus prevented attacks in an otherwise intractable chronic cluster headache patient previously treated unsuccessfully by surgical procedures to the trigeminal nerve. So far, 16 patients with intractable cronic cluster headache (CCH) and one intractable SUNCT patient have been successfully treated by hypothalamic stimulation. The procedures were well tolerated with no significant adverse events. Hypothalamic DBS is an efficacious and safe procedure to relieve otherwise intractable CCH and SUNCT. (copyright) Springer-Verlag Italia 2005
Chiari malformation-related headache: outcome after surgical treatment
No full textThe outcome of headache in a series of 135 operated CM1 is presented. Favorable results were obtained in 85% of atypical and 93% typical headache with the support of a multidisciplinary approach that restricted the indications for surgery
Difficulties in work-related activities among migraineurs are scarcely collected: results from a literature review.
No full textMigraine affects work productivity in terms of missed workdays and days with reduced productivity. In this literature review, we looked for papers addressing specific difficulties in work-related activities. Twenty-three papers were included in the review, reporting data on 51,135 patients. Results showed that there is some evidence for limitations in skills such as problem solving, and activities such as speaking and driving. However, the way in which problems with remunerative employment are addressed is limited to concepts such as reduced performance or inability to work as usual. Given the paucity of data, a return to patient-derived data will be needed to develop an assessment instrument that is able to collect information on headache-related problems in work activities
Difficulties in work-related activities among migraineurs are scarcely collected: results from a literature review.
No full textMigraine affects work productivity in terms of missed workdays and days with reduced productivity. In this literature review, we looked for papers addressing specific difficulties in work-related activities. Twenty-three papers were included in the review, reporting data on 51,135 patients. Results showed that there is some evidence for limitations in skills such as problem solving, and activities such as speaking and driving. However, the way in which problems with remunerative employment are addressed is limited to concepts such as reduced performance or inability to work as usual. Given the paucity of data, a return to patient-derived data will be needed to develop an assessment instrument that is able to collect information on headache-related problems in work activities
Milk ketone bodies assessment in a local Italian cow breed (Modenese) vs. Holstein and characterization of its physiological, reproductive and productive performances
No full textIn Northern Italy are present several autochthonous cattle breeds characterized by a small territorial diffusion. These breeds were breed for century the milk and meat production but also for work. The technical data show that these animals have a good reproductive performances and disease resistance and resilience. The objective of this study was to characterize some productive, reproductive and metabolic parameters (ketone bodies) in the Italian autochthonous cattle breeds Modenese, comparing them with those of Holstein and crossbred (F1=Modenese x Holstein; F2=Modenese x F1) breed in the same farm in order to understand if there is a different metabolic situation that can influence the reproductive performances. The milk samples have been taken at different times of lactation. Milk samples have been collected from the whole udder during morning milking and from a lactometer and analyzed by Gas chromatography-mass spectrometry to obtain the ketone bodies concentration. The reproductive (Open Days Period and number of Services Per Pregnancy) and productive (percentage and kg of protein between the 40th and 90th DIM) data have been recovered by the consultation of the farm registers and the APA (Provincial breeder association) data. On days open, number of services per pregnancy, % of proteins in milk, and kg of proteins in milk, a Spearman correlation analysis was applied. The comparative study between the races in the same breeding conditions is a fundamental tool to understand the correct reproductive and productive physiology of dairy cattle. Among the ketone bodies concentration, the Modenese breed showed a significant (p<0,05) lower concentration. A high concentration of ketone bodies is related with serious negative energy balance condition that can affect the reproductive performances. The F1, F2 and Modenese showed also better reproductive performances compared to Holstein, with a day’s open length in average between the 80-105 days. In conclusion, the better resilience against the negative energy balance and his adverse effects of Modenese cattle could be one of the phenomena underlying their better reproductive efficiency
Long-distance monitoring of physiological and environmental parameters for emergency operators
No full textThe recent disaster provoked by the earthquake in middle Italy has pointed out the need for minimizing risks endangering rescuers' lives. An European Project called ProeTEX (Protection e-Textiles: MicroNanoStructured fiber systems for Emergency-Disaster Wear) aims at developing smart garments able to monitor physiological and environmental parameters of emergency operators. The goal is to realize a wearable system detecting health state parameters of the users (heart rate, breathing rate, body temperature, blood oxygen saturation, position, activity and posture) and environmental variables (external temperature, presence of toxic gases and heat flux passing through the garments) and remotely transmitting useful information to the operation manager. This work presents an overview of the main features of the second prototype realized by ProeTEX with particular emphasis to the sensor's body network and the long distance transmission of signals
Bioencapsulation of Oocytes and Granulosa Cells
No full textA protocol for the encapsulation in sodium alginate of granulosa cells in primary culture and co-culture of oocyte-cumulus complexes is reported. Sodium alginate forms strong gels when jellified with barium ions, allowing the self-organization of cells into a 3D structure. This method of encapsulation is simple and cheap, allowing the culture of cells in a 3-dimensional fashion
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