740 research outputs found

    A geographic correlation study of the incidence of pancreatic and other cancers in whites

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    Ecologic analyses of cancer incidence rates may be helpful to formulate hypotheses on risk factors and mechanisms of poorly known neoplasms, such as pancreatic cancer. We calculated sex-specific pair-wise and partial (after adjustment for lung cancer incidence) correlations between the incidence of pancreatic cancer and that of 23 other cancers in two international sets of cancer incidence data: the recorded or estimated incidence for 2000 in 38 European countries and the recorded incidence in Whites for 1993-1997 in 35 cancer registries from North America and Oceania. In both sexes and datasets, a strong, highly significant correlation was present between the incidence of pancreatic cancer and that of lung and kidney cancer. For the latter, correlation coefficients in the European data were 0.71 in men and 0.74 in women (both p<0.0001); in the cancer registry data they were 0.57 (p=0.0004) in men and 0.45 (p=0.007) in women. The results on kidney cancer were not modified by adjustment for the correlation with lung cancer, were confirmed by the application of spatial regression models and, with the exception of men in the cancer registry data, were confirmed in sensitivity analyses restricted to the populations with data of best quality. Weaker, less consistent correlations were found for colorectal, endometrial, ovarian and bladder cancers. Tobacco smoking is a plausible explanation of the association between pancreatic and lung cancer; the association with kidney cancer likely reflects additional common etiologic and pathogenetic factors of the two neoplasms. © Springer 2006

    Some properties of set-valued stochastic integrals of multiprocesses with finite Castaing representations

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    The paper contains new properties of set-valued stochastic integrals defined as multifunctions with subtrajectory integrals equal to closed decomposable hulls of functional set-valued integrals defined in the author paper [8]. In particular, it is proved that such defined integrals for set-valued predictable square integrably bounded processes having finite Castaing representations are square integrably bounded. Up to now this property has not been proved. Unfortunately, in the general case the above boundedness problem is still open

    Trap depth distribution determines afterglow kinetics: a local model applied to ZnGa2O4:Cr3+ [Dataset]

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    Persistent luminescence (PersL) materials have applications in diverse fields such as smart signaling, anticounterfeiting, and in vivo imaging. However, the lack of a thorough understanding of the precise mechanisms that govern PersL makes it difficult to develop ways to optimize it. Here we present an accurate model to describe the various processes that determine PersL in ZnGa2O4:Cr3+ (ZGO:Cr), a workhorse material in the field. A set of rate equations has been solved, and a global fit to both charge/discharge and thermoluminescence measurements has been performed. Our results establish a direct link between trap depth distribution and afterglow kinetics and shed light on the main challenges associated with PersL in ZGO:Cr nanoparticles, identifying low trapping probability and optical detrapping as the main factors limiting the performance of ZGO:Cr, with a large margin for improvement. Our results highlight the importance of accurate modeling for the design of future afterglow materials and devices.This project has received funding from the BBVA Foundation Leonardo Grant for Physics Researchers 2023, and from MCIN/AEI/10.13039/501100011033 by European Union NextGeneration EU/PRTR under grant EUR2023-143467.- fig_2_a.txt : PL spectra (normalized to the R line) measured at 80K: Wavelength in nm (column 1), PL for 420 nm excitation (column 2), PL for 330 nm excitation (column 3) - fig_2_b.txt : PersL spectra (normalized to maximum): Wavelength in nm (column 1), PersL (column 2) - fig_2_c.txt : PL decay measured at 80 K: Time in s (column 1), counts for 420 nm excitation (column 2), fit for 420 nm excitation (column 3), residuals for 420 nm excitation (column 4), counts for 330 nm excitation (column 5), fit for 330 nm excitation (column 6), residuals for 330 nm excitation (column 7). - fig_3_a.txt : Charge/discharge curves: Time in s (column 1), measured intensity for maximum,medium and minimum excitation power (columns 2-4), fitted intensity for maximum,medium and minimum excitation power (columns 5-7). - fig_3_b_1.txt : Thermoluminescence charging at RT: Temperature in K (column 1), measured intensity (column 2), fitted intensity (column 3). - fig_3_b_2.txt : Thermoluminescence charging at 15 K: Temperature in K (column 1), measured intensity (column 2), fitted intensity (column 3). - fig_3_c.txt : Trap depth distribution (normalized to maximum): Trap depth in eV (column 1), rho(Et) (column 2). - fig_4_a_1.txt : Normalized charged traps density (columns colunms correspond to trap depth while rows correspond to time after charging). - fig_4_a_2.txt : Time axis of fig_4_a_1.txt in s - fig_4_a_3.txt : Trap depth axis of fig_4_a_1.txt in eV - fig_4_b.txt : PersL as a function of trap depth and time after excitation: Trap depth in eV (column 1), PersL after t1= 0 s, 1 s, 30 s, 60 s, and 300 s (columns 2-6). - fig_5_1.txt : PersL as a function of delta_E1 and delta_Et . Rows correspond to delta_E1 while columns correspond to delta_Et. - fig_5_2.txt : delta_E1 axis of fig_5_1.txt in eV - fig_5_3.txt : delta_Et axis of fig_5_1.txt in eVPeer reviewe

    Local heat flux measurements using a micro-machined integrated probe

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    Thermal flows are ubiquitous in natural and industrial systems, this is why they have been studied for decades. In these kinds of flows, an important quantity is the local heat flux, but it remains experimentally nearly unstudied since it is difficult to measure it. We introduce a new local convective heat flux probe, based on a joint measurement of temperature and velocity within the flow

    Histoire d'un patrimoine en révolution : Claude Bonnet de Paillerets, robin de Marvejols en Lozère de 1766 à 1815

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    and made constant efforts to obtain social distinction, as is demonstrated by the contracts he drew up. Loyal to each new regime, a son of the Enlightenment, Bonnet had little to do with the common man's world which was so different from his ideal of the family and from his way of life as a local worthy. The author carefully follows the dialectics of individual choice and social determination within a particularly significant case study.Thomas Castaing, Histoire d'un patrimoine en révolution : Claude Bonnet de Paillerets, robin de Marvejols en Lozère, de 1766 à 1815. Conseiller à la cour des comptes de Montpellier à la veille de la Révolution, mais en prise directe par tradition familiale avec les activités commerciales du négoce de laine, et du commerce maritime, Claude Bonnet de Paillerets est représentatif d'une stratégie de promotion sociale qui a privilégié le revenu noble à partir de la vente immobilière et mobilière. Gros propriétaire, il tire une bonne part de ses revenus de ses créances. L'épisode révolutionnaire affecte momentanément leur perception, mais ne freine que momentanément, grâce à des stratégies adaptées, l'accroissement d'une fortune finalement consolidée sous l'Empire. Les choix de ce notable s'expliquent par des facteurs autres qu'économiques : la recherche de l'intégration à l'élite de sa région et les efforts de distinction sociale, dont témoigne le renouvellement de ses contacts. Loyaliste vis-à- vis des nouveaux régimes quels qu'ils soient, homme des Lumières, il prend ses distances vis-à-vis d'un univers populaire auquel s'oppose son idéal de la famille comme son mode de vie de notable. Cette étude s'attache à suivre la dialectique des choix individuels et des déterminations sociales à partir d'un cas individuel significatif.Castaing Thomas. Histoire d'un patrimoine en révolution : Claude Bonnet de Paillerets, robin de Marvejols en Lozère de 1766 à 1815. In: Annales historiques de la Révolution française, n°290, 1992. pp. 517-537

    Microscopie électronique en transmission de la cuprite monocristalline déformée plastiquement

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    Single crystals of cuprite (Cu₂O) were plastically deformed along and compression axes. The specimens deformed at 250° C (0.35 TF) showed by T. E. M. four {110} slip systems. The specimens deformed at about 450° C (0.48 TF) showed both slip systems {001} and {101} simultaneously.Des monocristaux de cuprite Cu2O ont été déformés plastiquement par compression selon les directions et . Les températures des essais sont de l'ordre de 250° C (0,35 TK) ; la M. E. T. permet d'observer quatre systèmes de glissement {110} activés dans le premier cas. Dans le second cas, après déformation à environ 450°C (0,48 TF), on obtient les glissements {001} et {101} .Sieber Brigitte, Rivière Jean-Pierre, Castaing Jacques. Microscopie électronique en transmission de la cuprite monocristalline déformée plastiquement. In: Bulletin de Minéralogie, volume 102, 2-3, 1979. Mécanismes de déformation des minéraux et des roches

    Heavy versus standard silicone oil in the management of retinal detachment with macular hole in myopic eyes

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    PURPOSE: The purpose of this study was to compare pars plana vitrectomy (PPV) with 1000 cSt silicone oil endotamponade and PPV with densiron endotamponade for retinal detachment with macular hole and posterior staphyloma in highly myopic eyes. PATIENTS AND METHODS: In a prospective study, 30 eyes of 30 patients were randomly assigned to PPV and densiron (n = 15) or PPV with silicone oil (n = 15). All eyes had laser photocoagulation of the macular hole rim after PPV. Silicone oil or densiron was removed 12 weeks after surgery. Patients were followed-up for 6 months after oil removal. RESULTS: In the densiron group, the retinal reattachment rate was 100% with densiron in situ and 87% after its removal, and in the silicone oil group, the retinal reattachment rate was 67% with silicone oil in situ and 53.4% after oil removal. Thus, PPV with densiron had a better anatomical success rate than silicone oil (P = 0.04 with endotamponade and P = 0.05 after endotamponade removal). In both groups, paired comparison of preoperative and postoperative best-corrected visual acuity was not statistically significant (P = 0.08). CONCLUSION: Pars plana vitrectomy with densiron is a preferred surgical procedure for the repair of macular hole retinal detachment in highly myopic eyes with posterior staphyloma. © The Ophthalmic Communications Society, Inc

    Percutaneous Coronary Revascularization for Chronic Total Occlusions A Novel Predictive Score of Technical Failure Using Advanced Technologies

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    Objectives The aims of this study were to describe the 10-year experience of a single operator dedicated to chronic total occlusion (CTO) and to establish a model for predicting technical failure. Background During the last decade, the interest in percutaneous coronary interventions (PCIs) of chronic total occlusions (CTOs) has increased, allowing the improvement of success rate. Methods One thousand nineteen patients with CTO underwent 1,073 CTO procedures performed by a single CTO-dedicated operator. The study population was subdivided into 2 groups by time period: period 1 (January 2005 to December 2009, n = 378) and period 2 (January 2010 to December 2014, n = 641). Observations were randomly assigned to a derivation set and a validation set (in a 2:1 ratio). A prediction score was established by assigning points for each independent predictor of technical failure in the derivation set according to the beta coefficient and summing all points accrued. Results Lesions attempted in period 2 were more complex in comparison with those in period 1. Compared with period 1, both technical and clinical success rates significantly improved (from 87.8% to 94.4% [p = 0.001] and from 77.6% to 89.9% [p &lt; 0.001], respectively). A prediction score for technical failure including age ≥75 years (1 point), ostial location (1 point), and collateral filling Rentrop grade &lt;2 (2 points) was established, stratifying procedures into 4 difficulty groups: easy (0), intermediate (1), difficult (2), and very difficult (3 or 4), with decreasing technical success rates. In derivation and validation sets, areas under the curve were comparable (0.728 and 0.772, respectively). Conclusions With growing expertise, the success rate has increased despite increasing complexity of attempted lesions. The established model predicted the probability of technical failure and thus might be applied to grading the difficulty of CTO procedures
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