1,635 research outputs found
CODICE DI DIRITTO CANONICO E LEGGI COMPLEMENTARI COMMENTATO, III edizione
No full textCODICE DI DIRITTO CANONICO (E LEGGI COMPLEMENTARI) COMMENTATO. Traduzione ed edizione italiana aggiornata ed ampliata della 6a edizione curata dall'Istituto M. De Azpilcueta dell'Università di Navarra, con riferimenti al Codice dei canoni delle Chiese orientali, alla legislazione italiana e a quella particolare della CEI
La delibazione delle sentenze ecclesiastiche di nullità matrimoniale dopo la riforma del processo matrimoniale canonico
No full textSOMMARIO: 1. Il M.P. Mitis Iudex Dominus Iesus e la riforma ancora in itinere del processo
canonico di nullità matrimoniale. - 2. Conseguenze dell'abrogazione del M.P. Qua cura del 1938 sul
sistema concordatario italiano in materia di delibazione. - 3. Considerazioni sulla funzione filtro del
Supremo Tribunale della Segnatura Apostolica. - 4. La riforma alla prova del principio del giusto
processo (art. 111 della Costituzione). - 5. Sull'attuale sistema di diritto processuale italiano. - 6.
Analogie e differenze tra processo matrimoniale canonico e processo civile. - 7. Su alcune possibili
specifiche conseguenze negative della riforma sulla delibazione per violazione del diritto di difesa. -
8. Sulla natura giuridica del processus brevior. - 9. Sulla funzione degli indicatori previsti dall’art. 14
delle Regole procedurali. - 10. Inammissibilità dell'appello “non “manifestamente dilatorio" e sua
compatibilità con l'ordine pubblico processuale italiano. - 11. Conclusioni
Tapentadol: an overview of the safety profile
No full textEnrico Polati,1 Pier Luigi Canonico,2 Vittorio Schweiger,1 Massimo Collino31Anesthesia and Intensive Care, Pain Relief Center, Ospedale Policlinico GB Rossi, Verona, Italy; 2Dipartimento di Scienze del Farmaco, Università del Piemonte Orientale, Novara, Italy; 3Department of Drug Science and Technology, University of Turin, Turin, ItalyAbstract: Long-term opioid therapy may be associated with analgesic efficacy and also predictable adverse events, including cardiovascular and pulmonary events, gastrointestinal disorders, endocrinological harms, psychological problems, impairment of driving ability, and risk of abuse. These effects of opioids are mostly due to the wide expression of the mu receptor. Tapentadol, a centrally acting analgesic, is the first agent of a new class of drugs (MOR-NRI), since it combines two mechanisms of action, namely μ-opioid receptor (MOR) agonism and noradrenaline reuptake inhibition. Noteworthy, MOR activation with tapentadol is markedly lower compared with that exerted by classical opioids, thus likely resulting in fewer opioid-related adverse effects. In this review, we discuss current safety data on tapentadol, with a focus on some specific events, risk of abuse, and driving ability, a well-accepted proxy of the ability of taking critical decisions.Keywords: tapentadol, safety, pai
Diritto divino, diversità nazionali e diritto canonico
No full textLa comunicazione - presentata al XIII Congresso internazionale di diritto canonico - affronta il problema dei profili di diritto divino sottesi alla normativa canonica posta a tutela delle diversità nazionali, e del riscontro che tale tutela trova nella convergente attenzione dell'ordinamento italiano verso l'attività di culto degli italiani emigrati all'estero, evidenziata soprattutto attraverso l'analisi storica delle vicende storico-giuridiche riguardanti alcune "Chiese Italiane all'estero". Ciò viene fatto anche alla luce di una lunga ricerca d'archivio - i cui risultati vengono riportati nell'ampio apparato di note - che consente di affrontare da una prospettiva nuova e diversa la rilevanza che diversità nazionale e fenomeno religioso rivestono nella società attuale
Customer-choice organization of elderly-care: comparing local level processes in Sweden and Italy
No full textMany European countries have been undergoing significant restructuring of the public sector for at least the last two decades, due to the influence of the NPM reform discourse. The general intent of NPM reforms consists in shaping the public sector in a more business-like fashion dealing with the need of increasing efficiency and effectiveness in service provision. Since long (Hood, 1991) it has been discussed whether it is a kind of management useful “for all seasons”, and all context. The debate has gone back and forth. The last few years, critical books on the public sector reforms have been published (cf Dibben et al, 2004). Others have argued that New Public Management (NPM) is middle aging (Hood & Peters, 2004) or even dead (Dunleavy et al, 2005). Still, NPM inspired reforms are still being implemented “out there” in many countries. In this paper, we will compare the implementation in two such countries, Sweden and Italy.As this trend is spreading, it is also being transformed (Christensen & Lagreid, 2001) or translated (Czarniawska, 2005) in different ways depending on the peculiarities at local level.Typically NPM-based reforms discourse posit the need of a different institutional structure of the public sector: the role of the government is seen as the one of enabler and regulator of a complex institutional setting of public service providers. Along this way, complex and diversified arrangements of service delivery take place, ranging from public administrations and public enterprises provision to bottom-up, local level initiatives. In particular, market-driven reforms have stimulated the idea of unbundling services provision, in the effort of a more rationalistic use of taxpayers' resources. Public services previously offered by large municipal entities have been redeployed in market-like settings, administered both by purpose built entities that play as a direct emanation controlled by local municipalities or by private agents acting on the market. In this scenario public entrepreneurship tends to assume different configurations, according to the ways in which NPM principles have been implemented in different contexts. The remainder of this paper will be structured as follows. First we outline our theoretical framework based on previous studies of NPM and of new institutional perspectives within organization studies. Thereafter, we present the purpose othe this research before presenting the contextual peculiarities of the countries studied. Then, we specify the research questions, before discussing our methodology. The cases are subsequently presented one at a time, followed by discussion and conclusions
Analysis of the Influence of the Length Scales in a Boundary-Layer Model
No full textWe consider the Janjic (NCEP Office Note 437:61, 2001) boundary-layer model, which is one of the most widely used in numerical weather prediction models. This boundary-layer model is based on a number of length scales that are, in turn, obtained from a master length multiplied by constants. We analyze the simulation results obtained using different sets of constants with respect to measurements using sonic anemometers, and interpret these results in terms of the turbulence processes in the atmosphere and of the role played by the different length scales. The simulations are run on a virtual machine on the Chameleon cloud for low-wind-speed, unstable, and stable conditions
Pharmacological rationale for tapentadol therapy: a review of new evidence
No full textPatrizia Romualdi,1 Mariagrazia Grilli,2 Pier Luigi Canonico,3 Massimo Collino,4 Anthony H Dickenson5 1Department of Pharmacy and Biotechnologies Alma Mater Studiorum, University of Bologna, Bologna 40126, Italy; 2Laboratory of Neuroplasticity, Department Pharmaceutical Sciences, University of Piemonte Orientale, Novara 28100, Italy; 3Departiment of Pharmacological Sciences, University of Piemonte Orientale, Novara 28100, Italy; 4Department of Drug Science and Technology, University of Turin, Turin 10121, Italy; 5Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK Abstract: Chronic pain could be considered as a neurological disorder. Therefore, appropriate selection of the therapy, which should consider the pathophysiological mechanisms of pain, can result in a successful analgesic outcome. Tapentadol is an analgesic drug which acts both as a μ-opioid receptor (MOR) agonist and as a noradrenaline reuptake inhibitor (NRI), thereby generating a synergistic action in terms of analgesic efficacy, but not for the burden of adverse effects. Therefore, tapentadol can be defined as the first “MOR-NRI” drug. This molecule holds the potential to address at least some of the current limitations of analgesic therapy due to its unique mechanism of action and has shown to be safe and effective in the treatment of chronic pain of cancer and noncancer etiologies including nociceptive, neuropathic and mixed pain. In particular, the MOR component of tapentadol activity predominantly allows for analgesia in nociceptive pain; on the other hand, the NRI component contributes, now in a predominant manner, for analgesic efficacy in cases of neuropathic pain states. This paper will discuss recent pieces of evidence on the pathophysiology of pain, the background on tapentadol and then present some new studies on how the unique mechanism of action of tapentadol provides a key role in its analgesic efficacy in a number of pain states and with a favorable safety profile. Keywords: tapentadol, neuropathic pain, pain chronicizatio
Uso topico dei "fattori di crescita" nel trattamento delle ulcere flebostatiche "difficili" degli arti inferiori
No full textOrganisational models of notified certification bodies in the trans-european railway system: isomorphic pressures and allomorphic responses
No full textRegulatory and normative factors may affect the adoption of a specific organizational form, beyond the rationality that would suggest the selection among those derived by practice as plain technical solutions. New institutional theory points out the tendency for organizational forms to be deployed under the pressure of external and environmental conditions, regardless of their efficiency implications. It also emphasizes the role of social pressures imposed on organizations that influence organizational practices and structures. An articulated area of research in which verifying the adoption of alternative organisational structures may be provided by Notified Bodies, certification organisations operating in the European railway business system and established during the implementation phase of EU directives on trains interoperability
Metschnikowia pulcherrima selected strain for ethanol reduction in wine: Influence of cell immobilization and aeration condition
No full textOne of the most important problems in the winemaking field is the increase of ethanol content in wine. Wines with high ethanol level negatively affect wine flavor and human health. In this study, we evaluated the use of a selected strain of Metschnikowia pulcherrima in immobilized form and under different aeration conditions, to reduce the ethanol content evaluating the volatile profile of the resulting wines. In a preliminary screening the best conditions regarding free/immobilized cells, static/aerated fermentation and inoculation level were identified. Bench-Top fermentation trials with different aeration conditions showed that the use of M. pulcherrima selected strain with aeration flow of 20 mL/L/min during the first 72 h of fermentation, led an ethanol reduction of 1.38% (v/v) in comparison with Saccharomyces cerevisiae control strain. The analytical profile of the resulting wines did not show any negative feature. Indeed, the concentration of ethyl acetate, that above its sensory threshold impacts negatively the wine sensory profile, was found at an acceptable level. On the other hand, an increase in the concentration of significant fruity and flower compounds was found
- …
