333 research outputs found
Assembling two easy pieces: the geology of western Gondwana and plate tectonic theory - An introduction to the special volume
No full textEditorialE. Tohver, A.S. Collins, M. Babinski, R.I.F. Trindad
How many Babinski's signs are there? Quantos sinais de Babinski existem?
No full textIn addition to the famous sign described by Joseph Babinski, which is also known as Babinski's reflex, there are references in the literature to various other signs described by this famous disciple of J-M Charcot. This article reviews all the neurological signs described by Babinski.Além do famoso sinal descrito por Joseph Babinski, também definido como reflexo de Babinski, existem referências na literatura mundial de vários outros sinais descritos pelo famoso discípulo de J-M Charcot. Este artigo apresenta uma revisão de todos os sinais neurológicos descritos pelo professor Babinski
Regional and subunit-specific downregulation of acid-sensing ion channels in the pilocarpine model of epilepsy
No full textAcid-sensing ion channels (ASICs) constitute a recently discovered family of excitatory cation channels, structurally related to the superfamily of degenerin/epithelial sodium channels. ASIC1b and ASIC3 are highly expressed in primary sensory neurons and are thought to play a role in pain transmission related to acidosis. ASIC1a, ASIC2a, and ASIC2b are also distributed in the central nervous system where their function remains unclear. We investigated here the regulation of their expression during status epilepticus (SE), a condition in which neuronal overexcitation leads to acidosis. In animals treated with pilocarpine (380 mg/kg) to induce SE, we observed a marked decrease of ASlC2b mRNA levels in all hippocampal areas and of ASIC1a mRNA levels in the CA1-2 fields. These changes were also observed after protective treatment from neuronal cell death with diazepam (10 mg/kg) and pentobarbital (30 mg/kg). These findings suggest a key role of channels containing ASIC1a and ASIC2b subunits in both normal and pathological activity of hippocampus
Highly satisfactory alkynylation of alkenyl halides via Pd-catalyzed cross-coupling with alkynylzincs and its critical comparison with the Sonogashira alkynylation
No full textThe Pd-catalyzed alkynylation of various alkenyl halides and triflates with alkynylzincs proceeds well even with alkynyl derivatives containing electron-withdrawing groups. The reaction appears to be highly general. Noteworthy is that the corresponding Sonogashira reactions under various reported conditions are significantly less satisfactory in all cases performed in this study
Tracing final Gondwana assembly: age and provenance of key stratigraphic units in the southern Paraguay Belt, Brazil
No full textAbstract not availableBen McGee, Marly Babinski, Ricardo Trindade, Alan S. Collin
Babinski-Nageotte syndrome on magnetic resonance imaging.
No full textA 70-year-old woman developed left hypoglossal nerve palsy, a right hemiparesis sparing the face, and a typical left Wallenberg's syndrome. These symptoms resulted from a lesion in the left half of the medulla oblongata, suggesting Babinski-Nageotte syndrome, a rare cerebrovascular disease. This is the first case of ischemic infarction in the territory of the left vertebral artery and posterior inferior cerebellar artery demonstrated on magnetic resonance imaging. Severe bilateral lesions of the distal vertebral arteries demonstrated on digital subtraction angiography may have contributed to the development of this syndrome.</jats:p
Assessment of the dnieper alluvial riverbed stability affected by intervention discharge downstream of Kaniv Dam
No full textAlong the middle reaches of the Dnieper River in central Ukraine, braided riverbeds with many islands have developed in alluvial valleys. In the 1970s, six dams were commissioned, and respective monitoring infrastructure was installed. Riverbanks and valley floors composed of unconsolidated material have much lower bank strengths and are susceptible to fluvial erosion and bank collapse, particularly during the release of high flow volumes from hydropower dams. The regulation of the Dnieper River along a cascade of storage reservoirs caused significant changes in its active river channel and hydrological regime. In order to estimate channel stability downstream of the Kaniv reservoir, we conducted an analysis of the hydraulic conditions in terms of changes in flow velocity and propagation of waves caused by intervention water discharges from the Kaniv Hydroelectric Power Plant (HPP). In this paper, we assess the hydromorphological parameters of the studied river reach as well as the characteristics of the related erosion and deposition zones. Therefore, a monitoring framework for channel processes (MCP) downstream of the Kaniv HPP was installed. The analysis of the intervention discharge parameters was conducted based on measurements from July 2015. Channel stability was expressed by the following factors: Lohtin's number (L), Makkaveev's (Kc) factor of stability, and a complex index of stability (Mx) by Grishanin. This study shows that the velocity of artificial wave propagation may reach a speed of up to 74.4 kmh-1. The wave propagates for a distance of approx. 45 km within 65 min at a mean velocity of 37.4 kmh-1. The L, Kc, and Mx indicators used in this work showed that when water discharge increased (e.g., during typical peak-capacity operation), the channel becomes unstable and sediments are subject to erosion processes. The riverbed stability indicators clearly illustrate that an increase in parameter values is not dependent on the distance to the dam. The results are valuable for sustainable sediment management at catchment scale and hence, directly applicable in water management
Mammalian ASIC2a and ASIC3 subunits co-assemble into heteromeric proton-gated channels sensitive to Gd3+
No full textProton receptors of the acid-sensing ion channel (ASIC) family are expressed in sensory neurons and thus could play a critical role in the detection of noxious acidosis. To investigate the subunit composition of native ASICs in peripheral and central neurons, we coinjected human as well as rodent ASIC2a and ASIC3 subunits in Xenopus oocytes, The amplitudes of acid-induced biphasic responses mediated by co-expressed ASIC2a and ASIC3 subunits were much larger (as much as 20-fold) than the currents mediated by the respective homomers, clearly indicating functional association. The reversal potential of the ASIC2a+3 current (greater than or equal to+20 mV) reflected a cationic current mainly selective for sodium, The sensitivity to pH or amiloride of single versus co-expressed ASIC subunits was not significantly different; however, gadolinium ions inhibited ASICS and ASIC2a+3 responses with much higher potency (IC50 similar to 40 mu M) than the ASIC2a response (IC50 greater than or equal to 1 mM). Biochemical interaction between ASIC2a and ASIC3 subunits was demonstrated by co-purification from transfected human embryonic kidney (HEK293) cells and Xenopus oocytes. Our in situ hybridization data showed that rat ASIC2a and ASIC3 transcripts are colocalized centrally, whereas reverse transcription-polymerase chain reaction data led us to detect co-expression of human ASIC2a and ASIC3 subunits in trigeminal sensory ganglia, brain, and testis where they might coassemble into a novel subtype of proton-gated channels sensitive to gadolinium
Carte générale de l'Amérique séptentrionale : avec les posséssions Angloises dans cette partie du nouveau monde
No full textRelief shown pictorially.; Prime meridians: Paris and London.; Includes list of abbreviations, decorative cartouche, compass rose and 18 insets.; French key map state 3, according to Babinski.; Author attribution and publishing date taken from Babinski's analysis of Popple's 1733 map.; Map attributed to Le Rouge based on reference in W.P. Cumming's Southeast in early maps, no. 216. The earliest edition of Le Rouge's map appeared ca.1742.; Map based on Henry Popple's Map of the British Empire in America, with the French and Spanish settlements adjacent thereto (1733).; Library's acquisition record dates the map 1755. The OCLC record is for a 1763? edition. There is no evidence on the map as to its specific date
Chapter 50 Moema laminites: a newly recognized Neoproterozoic (?) glaciogenic unit, São Francisco Basin, Brazil - Photograph supplement
No full textCompanion photographs to the book chapter Rocha-Campos, Antonio C., de Brito Neves, Benjamin B., Babinski, Marly, dos Santos, Paulo R., de Oliveira, Sônia M. B., and Romano, A. 2011. “Moema laminites: a newly recognized Neoproterozoic (?) glaciogenic unit, São Francisco Basin, Brazil.” In: Arnaud, E., Halverson, G. P. and Shields-Zhou, G. (eds) The Geological Record of Neoproterozoic Glaciations. Geological Society, London, Memoirs, 36, 535-540
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