24 research outputs found
Bestimmung der Leistungsdeposition der Elektron-Zyklotron-Resonanz-Heizung (ECRH) durch deren Modulation während Plasmaexperimenten am Wendelstein 7-X
No full textBestimmung der Leistungsdeposition der Elektron-Zyklotron-Resonanz-Heizung (ECRH) durch deren Modulation während Plasmaexperimenten am Wendelstein 7-X
No full textFactors associated with anxiety and depression in cancer patients: Demographic factors and the role of demoralization and satisfaction with care
No full textObjective: Anxiety and depression are common in cancer patients and seem to affect quality of life, treatment compliance and even survival. Defining factors related to anxiety and depression and exploring the role of demoralization and satisfaction with care, could contribute to the improvement of patients' quality of life and quality of health services as well. Methods: A convenience sample of 150 cancer inpatients and outpatients from two oncology centers, with various types of solid tumors, participated in a prospective cross-sectional observational study. The psychometric tools used were the Greek versions of the Hospital Anxiety and Depression Scale, FAMCARE-Patient Scale and Oncology Palliative Care (FAMCARESCALE) and Demoralization Scale (DEMORALIZATION SCALE II, DS-II). Results: Patients mean age was 62 years (20–85 years) and 89 patients (59.3%) were women. Among patients, 33% had breast, 24% gastrointestinal and 15% lung cancer. Eighty-two patients (54.7%) had metastatic disease. Women showed higher rates of anxiety (p = 0.054). Anxiety was inversely related to age (p = 0.043) and positively correlated with time since diagnosis (p = 0.076). Unmarried patients presented with higher rates of depression (p = 0.026). Multiple linear regression showed a statistically significant impact of Demoralization factor ‘Meaning and Purpose’ on anxiety (p < 0.001, R2 = 36.3%) and depression (p < 0.001, R2 = 49%). Moreover, higher educational level (p = 0.038, R2 = 3.1%) is related to higher levels of anxiety and higher scores of FAMCARESCALE factor-Information/interaction with the health care professionals, is related to lower levels of depression (p = 0.008, R2 = 2.7%). Conclusions: The results highlight the significant impact of demoralization on anxiety and depression in cancer patients. Early recognition of demoralization and early referral to mental health professionals will hopefully alleviate the mental burden of cancer patients. © 2023 John Wiley & Sons Ltd
Change impact analysis: A systematic mapping study
No full textChange Impact Analysis (CIA) is the process of exploring the tentative effects of a change in other parts of a system. CIA is considered beneficial in practice, since it reduces cost of maintenance and the risk of software development failures. In this paper, we present a systematic mapping study that covers a plethora of CIA methods (by exploring 111 papers), putting special emphasis on how the CIA phenomenon can be quantified: to be efficiently managed. The results of our study suggest that: (a) the practical benefits of CIA cover any type of maintenance request (e.g., feature additions, bug fixing) and can help in reducing relevant cost; (b) CIA quantification relies on four parameters (instability, amount of change, change proneness, and changeability), whose assessment is supported by various metrics and predictors; and (c) in this vast research field, there are still some viewpoints that remain unexplored (e.g., the negative consequences of highly change prone artifacts), whereas others are over-researched (e.g., quantification of instability based on metrics). Based on our results, we provide: (a) useful information for practitioners—i.e., the expected benefits of CIA, and a list of CIA-related metrics, emphasizing on the provision of a detailed interpretation of their relation to CIA; and (b) interesting future research directions—i.e., over- and under-researched sub-fields of CIA. © 2020 Elsevier Inc
A Rare Case of Primary Carcinosarcoma of the Breast
No full textBreast carcinosarcoma is a rare malignancy accounting for approximately 0.08-0.2% of all breast tumours. It is a type of metaplastic mammary carcinoma displaying biphasic differentiation with epithelial and mesenchymal cellular characteristics with probable derivation from myoepithelial cells. A 65-year-old woman presented to our hospital with a two-month history of a rapidly growing mass in her left breast. Neither her medical nor family history was positive for malignancies. Subsequently, she underwent a fine needle aspiration, which was positive for adenocarcinoma, followed by a lumpectomy with axillary lymph node dissection. The histology revealed an undifferentiated neoplasm and the immunohistochemical cell staining was positive for pan-cytokeratin, SMA, Vimentin, and S-100, suggesting the diagnosis of breast carcinosarcoma with a triple-negative immunophenotype. There was no evidence of metastasis except for a positive lymph node, indicating a stage IIIA disease. Thus, she received adjuvant chemo-radiotherapy. However, 16 months later, she presented with metastatic disease, and unfortunately, she died 4 months later due to a systemic infection. Aggressive behavior, higher staging, chemoresistance, and higher proportion of triple negative breast cancer seem to be the main characteristics of breast carcinosarcoma, which is recognised as a separate entity from common invasive ductal carcinoma, with significantly worse clinical outcomes. © 2023 Maria Kiakou et al., published by Sciendo 2023
The implementation of palliative care in Greece: a position paper by the Palliative Care Working Group of the Hellenic society of Medical Oncology (HeSMO)
No full textThe global burden of cancer continues to rise, with projections indicating a 47% increase in new cases by 2040. The integration of oncology and palliative care has emerged as a vital approach to address the complex needs of cancer patients. This position paper, endorsed by the Palliative Care Working Group of the Hellenic Society of Medical Oncology (HeSMO), emphasizes the significance of early integration of palliative care with cancer-directed therapies. It highlights the benefits of this approach, including improved quality of life, symptom control, emotional well-being, and enhanced survival rates for patients. The paper also addresses the challenges of palliative care provision in Greece and advocates for comprehensive education for health-care professionals, especially oncologists and nurses, to effectively manage palliative care needs. The importance of multidisciplinary teams (MDTs), survivorship care plans (SCPs), home-based palliative care, and end-of-life care discussions is underscored. By aligning with international guidelines and recommendations, HeSMO strives to establish a supportive health-care system in Greece that offers equitable access to high-quality palliative care for all cancer patients, thus ensuring their well-being throughout their cancer journey
The implementation of palliative care in Greece: a position paper by the Palliative Care Working Group of the Hellenic society of Medical Oncology (HeSMO)
No full textThe global burden of cancer continues to rise, with projections indicating a 47% increase in new cases by 2040. The integration of oncology and palliative care has emerged as a vital approach to address the complex needs of cancer patients. This position paper, endorsed by the Palliative Care Working Group of the Hellenic Society of Medical Oncology (HeSMO), emphasizes the significance of early integration of palliative care with cancer-directed therapies. It highlights the benefits of this approach, including improved quality of life, symptom control, emotional well-being, and enhanced survival rates for patients. The paper also addresses the challenges of palliative care provision in Greece and advocates for comprehensive education for health-care professionals, especially oncologists and nurses, to effectively manage palliative care needs. The importance of multidisciplinary teams (MDTs), survivorship care plans (SCPs), home-based palliative care, and end-of-life care discussions is underscored. By aligning with international guidelines and recommendations, HeSMO strives to establish a supportive health-care system in Greece that offers equitable access to high-quality palliative care for all cancer patients, thus ensuring their well-being throughout their cancer journey
Improved calibration of the high-resolution tunable ECE system for power deposition and transport studies in Wendelstein 7-X
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