533 research outputs found
Could radiofrequency echographic multispectrometry (REMS) overcome the overestimation in BMD by dual-energy X-ray absorptiometry (DXA) at the lumbar spine?
No full textBackground: Osteoarthritis (OA) and vertebral fractures at the lumbar spine lead to an overestimation of bone mineral density (BMD). Recently, a new approach for osteoporosis diagnosis, defined as radiofrequency echographic multi-spectrometry (REMS), represents an innovative diagnostic tool that seems to be able to investigate bone quality and provide an estimation of fracture risk independent of BMD. The aim of this paper was to evaluate whether the use of REMS technology can favor the diagnosis of osteoporosis in subjects with an apparent increase in BMD. Methods: In a cohort of 159 postmenopausal (66.2 ± 11.6 yrs) women with overestimated BMD by DXA at the lumbar spine, we performed an echographic scan with the REMS technique. Results: The mean values of BMD at different skeletal sites obtained by the DXA and REMS techniques showed that the BMD T-scores by REMS were significantly lower than those obtained by the DXA technique both at the lumbar spine (p < 0.01) and at all femoral subregions (p < 0.05). In OA subjects, the percentage of women classified as “osteoporotic” on the basis of BMD by REMS was markedly higher with respect to those classified by DXA (35.1% vs 9.3%, respectively). Similarly, the REMS allows a greater number of fractured patients to be classified as osteoporotic than DXA (58.7% vs 23.3%, respectively). Conclusions: REMS technology by the analysis of native raw unfiltered ultrasound signals appears to be able to overcome the most common artifacts, such as OA and vertebral fracture of the lumbar spine, which affect the value of BMD by DXA. © 2022, The Author(s)
supplemental_materials_(revised)_20-1-2018 - Insulin-producing Cells from Adult Human Bone Marrow Mesenchymal Stromal Cells Could Control Chemically Induced Diabetes in Dogs: A Preliminary Study
No full textsupplemental_materials_(revised)_20-1-2018 for Insulin-producing Cells from Adult Human Bone Marrow Mesenchymal Stromal Cells Could Control Chemically Induced Diabetes in Dogs: A Preliminary Study by Mahmoud M. Gabr, Mahmoud M. Zakaria, Ayman F. Refaie, Amani M. Ismail, Sherry M. Khater, Sylvia A. Ashamallah, Maha M. Azzam, and Mohamed A. Ghoneim in Cell Transplantation</p
Electrical machine topologies: hottest topics in the electrical machine research community
No full textn this article, the state of the art in electrical machine design is outlined underlining the problems and challenges to be solved by engineers. As highlighted in this article, even if electrical machine design is often considered a mature issue from the technical and technological point of view, every year, new progresses and steps forward are made. New and more sophisticated design tools can be used worldwide, and innovative manufacturing processes, new insulation materials, and higher performance magnetic materials are available on the market. In addition, the evolution of the hardware used in digital control and new powerful power electronic devices represents a constant stimulus to improve the performance of electrical machines and reintroduce electrical machine structures that were not adopted in the past due to technological and technical constraints. As shown in this article, electrical machine design is an evergreen topic, and its importance is rising more each year under the push of more energy-saving requirements and higher-efficiency systems for electromechanical conversion. A green world will not be possible without electrical machines
Ability of radiofrequency echographic multispectrometry to identify osteoporosis status in elderly women with type 2 diabetes
No full textBackground: Patients with type 2 diabetes (T2DM) have an increased or normal BMD; however fragility fractures represent one of the most important complications of T2DM. Aims: This study aimed to evaluate whether the use of the Radiofrequency Echographic multi spectrometry (REMS) technique may improve the identification of osteoporosis in T2DM patients. Methods: In a cohort of 90 consecutive postmenopausal elderly (70.5 ± 7.6 years) women with T2DM and in 90 healthy controls we measured BMD at the lumbar spine (LS-BMD), at femoral neck (FN-BMD) and total hip (TH-BMD) using a dual-energy X-ray absorptiometry device; moreover, REMS scans were also carried out at the same axial sites. Results: DXA measurements were all higher in T2DM than in non-T2DM women; instead, all REMS measurements were lower in T2DM than in non T2DM women. Moreover, the percentage of T2DM women classified as “osteoporotic”, on the basis of BMD by REMS was markedly higher with respect to those classified by DXA (47.0% vs 28.0%, respectively). On the contrary, the percentage of T2DM women classified as osteopenic or normal by DXA was higher with respect to that by REMS (48.8% and 23.2% vs 38.6% and 14.5%, respectively). T2DM women with fragility fractures presented lower values of both BMD-LS by DXA and BMD-LS by REMS with respect to those without fractures; however, the difference was significant only for BMD-LS by REMS (p < 0.05). Conclusions: Our data suggest that REMS technology may represent a useful approach to enhance the diagnosis of osteoporosis in patients with T2DM
The AYTY dataset for 1H212C16O
No full textThe dataset is an archive of ExoMol page, https://exomol.com/data/molecules/H2CO/1H2-12C-16O/AYTY.Please check the reference details according to the following description or directly from the website.
NB: The html description skips data which are not included in the current version for the purpose of simplicity. Please check H2CO_1H212C16O_AYTY.md for detailed information.
Definitions file
1H2-12C-16O__AYTY.def[14.89 KB]
References:
1. Tennyson, J., Yurchenko, S. N., Al-Refaie, A. F., Clark, V. H. J., Chubb, K. L., Conway, E. K., Dewan, A., Gorman, M. N., Hill, C., Lynas-Gray, A. E., Mellor, T., McKemmish, L. K., Owens, A., Polyansky, O. L., Semenov, M., Somogyi, W., Tinetti, G., Upadhyay, A., Waldmann, I., Wang, Y., Wright, S., Yurchenko, O. P., "The 2020 release of the ExoMol database: molecular line lists for exoplanet and other hot atmospheres", J. Quant. Spectrosc. Rad. Transf., 255, 107228 (2020). [https://doi.org/10.1016/j.jqsrt.2020.107228]
Spectroscopic Model
https://exomol.com/models/H2CO/1H2-12C-16O/AYTY/
AYTY: line list
NB: These data are not included in the current version on Zenodo because the data are over Zenodo upload cap, 50GB
Data can be accessed via: https://exomol.com/data/molecules/H2CO/1H2-12C-16O/AYTY
References:
1. Al-Refaie, A. F., Yachmenev, A., Tennyson, J.Yurchenko, S. N., "ExoMol line lists VIII: A variationally computed line list for hot formaldehyde", Monthly Notices of the Royal Astronomical Society 448, 1704-1714 (2015). [http://dx.doi.org/10.1093/mnras/stv091][15AlYaTe.H2CO]
AYTY: partition function
A variationally computed line list for hot formaldehyde
1H2-12C-16O__AYTY.pf[25.39 KB]Partition Function for (1H)2(12C)(16O)
References:
1. Al-Refaie, A. F., Yachmenev, A., Tennyson, J.Yurchenko, S. N., "ExoMol line lists VIII: A variationally computed line list for hot formaldehyde", Monthly Notices of the Royal Astronomical Society 448, 1704-1714 (2015). [http://dx.doi.org/10.1093/mnras/stv091][15AlYaTe.H2CO]
AYTY: opacity
A variationally computed line list for hot formaldehyde
1H2-12C-16O__AYTY.R1000_0.3-50mu.ktable.NEMESIS.kta[232.01 MB]NEMESIS k-tables at R= 1000 (0.3-50mu) in NEMESIS-kta format: AYTY (1H)2(12C)(16O) line list.
1H2-12C-16O__AYTY.R15000_0.3-50mu.xsec.TauREx.h5[348.39 MB]TauREx cross sections at R= 15000 (0.3-50mu) in HDF5 format: AYTY (1H)2(12C)(16O) line list.
1H2-12C-16O__AYTY.R1000_0.3-50mu.ktable.ARCiS.fits.gz[337.15 MB]ARCiS k-tables at R= 1000 (0.3-50mu) in fits format (gzipped): AYTY (1H)2(12C)(16O) line list.
1H2-12C-16O__AYTY.R1000_0.3-50mu.ktable.petitRADTRANS.h5[370.98 MB]petitRADTRANS k-tables at R= 1000 (0.3-50mu) in HDF5 format: AYTY (1H)2(12C)(16O) line list.
References:
1. Al-Refaie, A. F., Yurchenko, S. N., Yachmenev, A., Tennyson, J., "ExoMol line lists IX: A variationally computed line-list for hot formaldehyde", Monthly Notices of the Royal Astronomical Society 448, 1704-1714 (2015). [https://doi.org/10.1093/mnras/stv091][15AlYuTe.H2CO]
2. Chubb, K. L., Rocchetto, M., Yurchenko, S. N., Min, M., Waldmann, I., Barstow, J. K., Molliere, P., Al-Refaie, A. F, Phillips, M. W., Tennyson, J., "The ExoMolOP database: Cross sections and k-tables for molecules of interest in high-temperature exoplanet atmospheres", Astronomy and Astrophysics 646, A21 (2020). [http://dx.doi.org/10.1051/0004-6361/202038350][20ChRoYu.]
AYTY: other States files
NB: These data are not included in current version on Zenodo
Data can be accessed via: https://exomol.com/data/molecules/H2CO/1H2-12C-16O/AYT
Comanagement of surgical patients between neurosurgeons and internal-medicine clinicians: observational cohort study
No full textThe rising prevalence of chronic diseases have contributed to a population with high complexity of care. There has been an increasing need for a new organizational model based on the interaction in the same department between the specialist skills of surgical and medical disciplines. This study aims to describe the implementation of a hospitalist co-management program in a Neurosurgery Department (ND) and its impact on the incidence of medical complications, 30 days readmission rate for medical causes, number of transfers to Intensive Care Units (ICU)/Neurosurgical Intensive Care Unit (NICU) or to medical wards (MW), length-of stay (LOS), mortality and satisfaction of health workers. We conducted an observational study comparing changes before and after the Internal medicine-Neurosurgical Comanagement (INC) intervention. We conducted a retrospective evaluation of patients enrolled before the INC intervention and a prospective evaluation of those enrolled after the INC intervention was implemented. We defined the pre-INC intervention group as 380 patients admitted to the ND for neurosurgical disease between January 2022 and April 2022 and the post-INC intervention group as 367 patients admitted to the ND between January 2023 and April 2023. INC intervention was associated with a significant decrease in medical complications during the hospital stay (OR 0.52; 95% CI; 0.39–0.70, p < 0.001), 30 days in-hospital readmission for medical reasons (OR 0.95; 95% CI 0.93–0.97, p < 0.001) and numbers of transfers to ICU/NICU (OR 0.31; 95% CI; 0.17–0.55, p < 0.001) or MW (OR 0.51; 95% CI 0.33–0.77, p = 0.002). During the INC intervention period, we observed a high satisfaction rate in health workers, evaluated by standardized questionnaire. In our study, LOS, in-hospital mortality and 30-day mortality were not significantly associated with INC. Hospitalist co-management in Neurosurgical Departments was associated with a reduced incidence of medical complications, 30-days in-hospital readmission and numbers of transfers to ICU/NICU or MW with a high satisfaction rate among healthcare workers, but without a significant decrease in LOS and mortality rate
The SAlTY dataset for 31P1H3
No full textThe dataset is an archive of ExoMol page, https://exomol.com/data/molecules/PH3/31P-1H3/SAlTY.Please check the reference details according to the following description or directly from the website.
NB: The html description skips data which are not included in the current version for the purpose of simplicity. Please check PH3_31P1H3_SAlTY.md for detailed information.
Definitions file
31P-1H3__SAlTY.def[12.33 KB]
References:
1. Tennyson, J., Yurchenko, S. N., Al-Refaie, A. F., Clark, V. H. J., Chubb, K. L., Conway, E. K., Dewan, A., Gorman, M. N., Hill, C., Lynas-Gray, A. E., Mellor, T., McKemmish, L. K., Owens, A., Polyansky, O. L., Semenov, M., Somogyi, W., Tinetti, G., Upadhyay, A., Waldmann, I., Wang, Y., Wright, S., Yurchenko, O. P., "The 2020 release of the ExoMol database: molecular line lists for exoplanet and other hot atmospheres", J. Quant. Spectrosc. Rad. Transf., 255, 107228 (2020). [https://doi.org/10.1016/j.jqsrt.2020.107228]
Spectroscopic Model
https://exomol.com/models/PH3/31P-1H3/SAlTY/
SAlTY: line list
NB: These data are not included in the current version on Zenodo because the data are over Zenodo upload cap, 50GB
Data can be accessed via: https://exomol.com/data/molecules/PH3/31P-1H3/SAlTY
References:
1. Sousa-Silva, C., Al-Refaie, A. F., Tennyson, J., Yurchenko, S. N., "ExoMol line lists VII: The rotation-vibration spectrum of phosphine up to 1500 K", Monthly Notices of the Royal Astronomical Society 446, 2337-2347 (2014). [http://dx.doi.org/10.1093/mnras/stu2246][14SoAlTe.PH3]
SAlTY: partition function
A computed hot line list for phosphine.
SAlTY_readme.txt[1.62 KB]Documentation for the line list of the SAlTY PH3 data set.
31P-1H3__SAlTY.pf[25.39 KB]Partition Function for (31P)(1H)3
References:
1. Sousa-Silva, C., Al-Refaie, A. F., Tennyson, J., Yurchenko, S. N., "ExoMol line lists VII: The rotation-vibration spectrum of phosphine up to 1500 K", Monthly Notices of the Royal Astronomical Society 446, 2337-2347 (2014). [http://dx.doi.org/10.1093/mnras/stu2246][14SoAlTe.PH3]
SAlTY: opacity
A computed hot line list for phosphine.
31P-1H3__SAlTY.R1000_0.3-50mu.ktable.ARCiS.fits.gz[339.54 MB]ARCiS k-tables at R= 1000 (0.3-50mu) in fits format (gzipped): SAlTY (31P)(1H)3 line list.
31P-1H3__SAlTY.R1000_0.3-50mu.ktable.petitRADTRANS.h5[370.98 MB]petitRADTRANS k-tables at R= 1000 (0.3-50mu) in HDF5 format: SAlTY (31P)(1H)3 line list.
31P-1H3__SAlTY.R1000_0.3-50mu.ktable.NEMESIS.kta[232.01 MB]NEMESIS k-tables at R= 1000 (0.3-50mu) in NEMESIS-kta format: SAlTY (31P)(1H)3 line list.
31P-1H3__SAlTY.R15000_0.3-50mu.xsec.TauREx.h5[348.39 MB]TauREx k-tables at R= 15000 (0.3-50mu) in HDF5 format: SAlTY (31P)(1H)3 line list.
References:
1. Sousa-Silva, C., Al-Refaie, A. F., Tennyson, J., Yurchenko, S. N., "ExoMol line lists VII: The rotation-vibration spectrum of phosphine up to 1500 K", Monthly Notices of the Royal Astronomical Society 446, 2337-2347 (2014). [http://dx.doi.org/10.1093/mnras/stu2246][14SoAlTe.PH3]
2. Chubb, K. L., Rocchetto, M., Yurchenko, S. N., Min, M., Waldmann, I., Barstow, J. K., Molliere, P., Al-Refaie, A. F, Phillips, M. W., Tennyson, J., "The ExoMolOP database: Cross sections and k-tables for molecules of interest in high-temperature exoplanet atmospheres", Astronomy and Astrophysics 646, A21 (2020). [http://dx.doi.org/10.1051/0004-6361/202038350][20ChRoYu.
Methyl-CpG-binding protein 2 (MECP2) mutation type is associated with bone disease severity in Rett syndrome
No full textBackground: More than 95% of individuals with RTT have mutations in methyl-CpG-binding protein 2 (MECP2), whose protein product modulates gene transcription. The disorder is caused by mutations in a single gene and the disease severity in affected individuals can be quite variable. Specific MECP2 mutations may lead phenotypic variability and different degrees of disease severity. It is known that low bone mass is a frequent and early complication of subjects with Rett syndrome. As a consequence of the low bone mass Rett girls are at an increased risk of fragility fractures. This study aimed to investigate if specific MECP2 mutations may affects the degree of involvement of the bone status in Rett subjects. Methods: In 232 women with Rett syndrome (mean age 13.8 ± 8.3 yrs) we measured bone mineral density at whole body and at femur (BMD-FN and BMD-TH) by using a DXA machine (Hologic QDR 4500). QUS parameters were assessed at phalanxes by Bone Profiler-IGEA (amplitude dependent speed of sound: AD-SoS and bone transmission time: BTT). Moreover, ambulation capacity (independent or assisted), fracture history and presence of scoliosis were assessed. We divided the subjects with the most common point mutations in two group based on genotype-phenotype severity; in particular, there has been consensus in recognising that the mutations R106T, R168X, R255X, R270X are considered more severe. Results: As aspect, BMD-WB, BMD-FN and BMD-TH were lower in subjects with Rett syndrome that present the most severe mutations with respect to subjects with Rett syndrome with less severe mutations, but the difference was statistically significant only for BMD-FN and BMD-TH (p < 0.05). Also both AD-SoS and BTT values were lower in subjects that present the most severe mutations with respect to less severe mutations but the difference was not statistically significant. Moreover, subjects with Rett syndrome with more severe mutations present a higher prevalence of scoliosis (p < 0.05) and of inability to walk (p < 0.05). Conclusion: This study confirms that MECP2 mutation type is a strong predictor of disease severity in subjects with Rett syndrome. In particular, the subjects with more severe mutation present a greater deterioration of bone status, and a higher prevalence of scoliosis and inability to walk
The AYTY dataset for 1H212C16O
No full textThe dataset is an archive of ExoMol page, https://exomol.com/data/molecules/H2CO/1H2-12C-16O/AYTY.Please check the reference details according to the following description or directly from the website. NB: The html description skips data which are not included in the current version for the purpose of simplicity. Please check H2CO_1H212C16O_AYTY.md for detailed information. Definitions file 1H2-12C-16O__AYTY.def[14.89 KB] References: 1. Tennyson, J., Yurchenko, S. N., Al-Refaie, A. F., Clark, V. H. J., Chubb, K. L., Conway, E. K., Dewan, A., Gorman, M. N., Hill, C., Lynas-Gray, A. E., Mellor, T., McKemmish, L. K., Owens, A., Polyansky, O. L., Semenov, M., Somogyi, W., Tinetti, G., Upadhyay, A., Waldmann, I., Wang, Y., Wright, S., Yurchenko, O. P., "The 2020 release of the ExoMol database: molecular line lists for exoplanet and other hot atmospheres", J. Quant. Spectrosc. Rad. Transf., 255, 107228 (2020). [https://doi.org/10.1016/j.jqsrt.2020.107228] Spectroscopic Model https://exomol.com/models/H2CO/1H2-12C-16O/AYTY/ AYTY: line list NB: These data are not included in the current version on Zenodo because the data are over Zenodo upload cap, 50GB Data can be accessed via: https://exomol.com/data/molecules/H2CO/1H2-12C-16O/AYTY References: 1. Al-Refaie, A. F., Yachmenev, A., Tennyson, J.Yurchenko, S. N., "ExoMol line lists VIII: A variationally computed line list for hot formaldehyde", Monthly Notices of the Royal Astronomical Society 448, 1704-1714 (2015). [http://dx.doi.org/10.1093/mnras/stv091][15AlYaTe.H2CO] AYTY: partition function A variationally computed line list for hot formaldehyde 1H2-12C-16O__AYTY.pf[25.39 KB]Partition Function for (1H)2(12C)(16O) References: 1. Al-Refaie, A. F., Yachmenev, A., Tennyson, J.Yurchenko, S. N., "ExoMol line lists VIII: A variationally computed line list for hot formaldehyde", Monthly Notices of the Royal Astronomical Society 448, 1704-1714 (2015). [http://dx.doi.org/10.1093/mnras/stv091][15AlYaTe.H2CO] AYTY: opacity A variationally computed line list for hot formaldehyde 1H2-12C-16O__AYTY.R1000_0.3-50mu.ktable.NEMESIS.kta[232.01 MB]NEMESIS k-tables at R= 1000 (0.3-50mu) in NEMESIS-kta format: AYTY (1H)2(12C)(16O) line list. 1H2-12C-16O__AYTY.R15000_0.3-50mu.xsec.TauREx.h5[348.39 MB]TauREx cross sections at R= 15000 (0.3-50mu) in HDF5 format: AYTY (1H)2(12C)(16O) line list. 1H2-12C-16O__AYTY.R1000_0.3-50mu.ktable.ARCiS.fits.gz[337.15 MB]ARCiS k-tables at R= 1000 (0.3-50mu) in fits format (gzipped): AYTY (1H)2(12C)(16O) line list. 1H2-12C-16O__AYTY.R1000_0.3-50mu.ktable.petitRADTRANS.h5[370.98 MB]petitRADTRANS k-tables at R= 1000 (0.3-50mu) in HDF5 format: AYTY (1H)2(12C)(16O) line list. References: 1. Al-Refaie, A. F., Yurchenko, S. N., Yachmenev, A., Tennyson, J., "ExoMol line lists IX: A variationally computed line-list for hot formaldehyde", Monthly Notices of the Royal Astronomical Society 448, 1704-1714 (2015). [https://doi.org/10.1093/mnras/stv091][15AlYuTe.H2CO] 2. Chubb, K. L., Rocchetto, M., Yurchenko, S. N., Min, M., Waldmann, I., Barstow, J. K., Molliere, P., Al-Refaie, A. F, Phillips, M. W., Tennyson, J., "The ExoMolOP database: Cross sections and k-tables for molecules of interest in high-temperature exoplanet atmospheres", Astronomy and Astrophysics 646, A21 (2020). [http://dx.doi.org/10.1051/0004-6361/202038350][20ChRoYu.] AYTY: other States files NB: These data are not included in current version on Zenodo Data can be accessed via: https://exomol.com/data/molecules/H2CO/1H2-12C-16O/AYTY {"references": ["Tennyson, J., Yurchenko, S. N., Al-Refaie, A. F., Clark, V. H. J., Chubb, K. L., Conway, E. K., Dewan, A., Gorman, M. N., Hill, C., Lynas-Gray, A. E., Mellor, T., McKemmish, L. K., Owens, A., Polyansky, O. L., Semenov, M., Somogyi, W., Tinetti, G., Upadhyay, A., Waldmann, I., Wang, Y., Wright, S., Yurchenko, O. P., \"The 2020 release of the ExoMol database: molecular line lists for exoplanet and other hot atmospheres\", J. Quant. Spectrosc. Rad. Transf., 255, 107228 (2020). \[https://doi.org/10.1016/j.jqsrt.2020.107228](https://doi.org/10.1016/j.jqsrt.2020.107228)\", "Al-Refaie, A. F., Yachmenev, A., Tennyson, J.Yurchenko, S. N., \"ExoMol line lists VIII: A variationally computed line list for hot formaldehyde\", Monthly Notices of the Royal Astronomical Society 448, 1704-1714 (2015). [http://dx.doi.org/10.1093/mnras/stv091][15AlYaTe.H2CO]", "Al-Refaie, A. F., Yurchenko, S. N., Yachmenev, A., Tennyson, J., \"ExoMol line lists IX: A variationally computed line-list for hot formaldehyde\", Monthly Notices of the Royal Astronomical Society 448, 1704-1714 (2015). [https://doi.org/10.1093/mnras/stv091][15AlYuTe.H2CO]", "Chubb, K. L., Rocchetto, M., Yurchenko, S. N., Min, M., Waldmann, I., Barstow, J. K., Molliere, P., Al-Refaie, A. F, Phillips, M. W., Tennyson, J., \"The ExoMolOP database: Cross sections and k-tables for molecules of interest in high-temperature exoplanet atmospheres\", Astronomy and Astrophysics 646, A21 (2020). [http://dx.doi.org/10.1051/0004-6361/202038350][20ChRoYu.]"]
Surface PM machine parameter selection for wide field-weakening applications
No full textRecent work on fractional-slot pitch, concentrated winding (FSCW) surface PM machines has shown that these machines can achieve a wide constant-power speed range. This paper shows that defining the allowable machine design parameter plane using the characteristic current and the peak back-emf provides useful insights into how application requirements restrict the machine parameters. The parameter plane also shows the influence of changing the parameters on the machine's current rating and magnet losses. As an example of a practical application, the parameter plane is used to study the FreedomCAR traction motor drive requirements and the characteristics of five FSCW surface PM machine designs.W.L. Soong, P.B. Reddy, A.M. El-Refaie, T.M. Jahns and N. Ertugru
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