1,721,817 research outputs found
Nutritional value of formulas in the treatment of cow's milk allergy
No full textThe prevalence of food allergy (FA) and cow's milk allergy (CMA) are increasing in pediatric population worldwide. The only available treatment for FA-affected children is the avoidance of the offending food allergen. [...] Efforts should be targets toward demonstrating the safety, nutritional adequacy, and efficacy of milk proteins or milk protein fractions as well as overcoming hurdles related to cost, supply, and manufacturing
Fine particles and children's respiratory function in two primary schools in Milan, Italy
No full textBackground: Few data exists about relationship between respiratory function and different types of air particulates. Aim: To relate fine particles concentrations to children's respiratory function and inflammation. Methods: We selected two schools in Milan, school 1 located near a large park and school 2 downtown. From September 23th to October 3rd 2008, we sampled in and outdoor PM1, PM2,5 and PM10 (mcg/m3) by Optical Particle Counters (OPC 1,107 environcheck and OPC 1,108 dustcheck). We enrolled 232 children; 149 attending school 1, 83 school 2. All underwent spirometry and exhaled fraction of nitric oxide (FeNO) dosage. Results: Fine particles [mean (SD)] are significantly higher in school 2, except schooltime (7:30-18:30) indoor PM10, that increases in both schools (table). Respiratory function is normal in all children but the percentage values (mean [SD] of FEV1, FVC and PEF are different in the two schools (106,1 [11,85] vs 102,1 [12,87] p=0,007; 100,4 [10,77] vs 95,84 [11,45] p=0,011; 92,8 [14,62] vs 88,6 [13,63] p=0,31). Mean (SD) concentration of FeNO (ppb) is normal in both (14,5[9,16] vs 17,1 [12,7] p=0,456). Conclusion: Although PM10 indoor is higher in school 1, respiratory function is better. PM10 couldn't be the most useful indicator of air quality and its effects on children pulmunary health
Dietary Treatment of PKU : Metabolic and Nutritional Implications
No full textHyperphenylalaninemia (HPA) is an inborn error of phenylalanine metabolism, due to the deficiency of phenylalanine hydroxilase, which leads to the increase of phenylalanine and its metabolites in plasma, urine and central nervous system, with developmental delay. Only 2% of cases is due to tetrahydrobiopterin deficiency. The only therapy at present at our disposal is a diet-therapy characterized by natural nutrients (like fruit and vegetables) and phenylalanine-free protein products together with aminoacids powder. The diet therapy has to be started as soon as possible and has to be followed all life long. Since the first attempt to treat a PKU patient with a low-Phe diet, new challanges in the management of PKU have to be considered: optimal growth, optimal nutritional status, optimal compliance and quality of life of the patients. PKU subjects need special attention in the definition of optimal supplementation of nutrients, which may be insufficient in relation to the type of diet and may otherwise manifest symptoms of deficit. In particular, it is necessary to pay great attention to the long-chain polyunsaturated fatty acid (LC-PUFA) levels in relation to correct development of the central nervous system. On the basis of numerous beneficial effects currently known, a permanent supplementation with LC-PUFA, in particular with docosahexaenoic acid, should be considered. Moreover, new formulas, Phe-free peptides, and "modulated" amino acid preparations might help in preventing nutritional dificiencies and imbalances, with the ultimate aim of improving growth. New strategies-such as supply of tetrahydrobiopterin- need to be optimized in terms of targets, patients and expected outcomes
Le torri di avvistamento ed il sistema di comunicazione. La costa ligure tra Rapallo e Portofino
No full textPubblicazione finanziata con i fondi MIUR nell’ambito dei programmi di ricerca Prin 2003-2005: “Architetture e luoghi del
Mediterrane. Misura, analisi, storia, comprensione, valutazione per la gestione dei processi trasformativi” (coordinatore nazionale prof. M. Giovannini
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