71 research outputs found
Identity and consumption practices of Northamptonshire Caribbeans c.1955-1989
No full textThe objective of this thesis is to delineate and analyse Northamptonshire Caribbeans' consumption c.1955-1989. Author-collected and other oral histories alongside complementary primary and secondary references dovetail to unearth and analyse aspects of Post-War Caribbean consumption in a British provincial location that have been significantly unexplored previously. Central to the argument is the contention that identity is fundamentally significant in comprehending and analysing Northamptonshire Caribbeans' consumption. Various conceptualisations of identity facilitated development of consumer materialisations and aspirations. This thesis explores how multiple forms of identity as Caribbean, Black and British people were significant in shaping local Caribbeans' consumption. The succeeding pages address and analyse how these multiple identities influenced consumption and how provincial consumer behaviour was shaped by Caribbeans' relative co-ethnic isolation in Northamptonshire. Chapter 3 delineates and analyses consumer practices and practicalities of Northamptonshire Caribbeans. Integral within these consumer practices and practicalities are changes in consumption over time, intergenerational differences in consumption, as well as aspects of consumption that could be considered 'typical' and/or 'atypical' Northamptonshire Caribbean consumption; all of which are incorporated within this chapter. Chapter 4 connects identity and consumption through enhancing understanding of Northamptonshire Caribbeans' consumer networks. These networks interacted with the combination of identities local Caribbeans psychologically felt part of within various Caribbean, Black and British permutations. Furthermore, such identities varied more widely amongst the younger generation than their co-ethnic elders, a concept which is also addressed. Education and cultural currency are two novel strands through which to analyse connections between consumption and identity. The final two chapters deploy these concepts in an innovative manner creating and developing greater understanding of Northamptonshire Caribbeans' consumption. Chapter 5 expounds on the concept that education can be used as consumption whilst shaping future consumer behaviour, both ideas significantly under-explored previously. Chapter 6 introduces the theory of cultural currency, the idea that aspects of culture have finite, but changing, values and must be shared to have value similar to monetary currencies having exchange values for other monetary currencies. This chapter demonstrates how Northamptonshire Caribbeans shared aspects of Caribbean culture as cultural currency, fostering co-ethnic strength whilst gaining inter-ethnic respect for Caribbeans. Through comprehending Caribbean identity, correlations between empirical and social history, local consumption, as well as educational and cultural circumstances that stimulated and inspired Northamptonshire Caribbeans, this thesis distinctively illuminates how local Caribbeans' consumption interacted with various permutations of Afro-Caribbean, Black and/or British identities whilst representing idiosyncratic local nodes within these larger amalgamations
Watley, Louanne, b. 1937
No full textFinding aid only for Manuscripts Small Collection 3606. Correspondence of Watley, of Chapel Hill, North Carolina, and poet, author and Appalachian studies scholar Jim Wayne Miller regarding writing workshops and grant-funded projects. Includes poems of Watley and a detailed critique by Miller
Data Management Plan Examples Database
No full textThis dataset is comprised of a collection of example DMPs from a wide array of fields; obtained from a number of different sources outlined in the README. Data included/extracted from the examples included the discipline and field of study, author, institutional affiliation and funding information, location, date modified, title, research and data-type, description of project, link to the DMP, and where possible external links to related publications, grant pages, or French language versions.
This CSV document serves as the content for a McMaster Data Management Plan (DMP) Database as part of the Research Data Management (RDM) Services website, located at https://u.mcmaster.ca/dmps. Other universities and organizations are encouraged to link to the DMP Database or use this dataset as the content for their own DMP Database.
This dataset will be updated regularly to include new additions and will be versioned as such. We are gathering submissions at https://u.mcmaster.ca/submit-a-dmp to continue to expand the collection
Watley, M.
No full textSee entry in Henry County, volume 2, page 4: https://digital.archives.alabama.gov/digital/collection/voter1867/id/376
Watley, M. W.
No full textSee entry in Tuscaloosa County, volume 1, page 34: https://digital.archives.alabama.gov/digital/collection/voter1867/id/491
The cultural currency of Afro-Caribbeans in Northamptonshire c. 1960-1990
No full textThis article addresses how Northamptonshire Afro-Caribbeans c. 1960-1990 were simultaneously part of the transformation from people of the Caribbean with individual island identities/nationalities into Afro-Caribbean British people whilst helping to shape this ethno-racial development. Oral history has been integral in conducting this research, with past Northamptonshire Black History Association (NBHA) interviews from 2002-2005 being a great asset to the interviews conducted by the author in 2009-2010 Economic concepts involving monetary currencies and flight to quality will be used to show how these monetary philosophies can help historians understand how culture and its manifestations are forms, and have systems, of exchange. These monetary concepts will also be used to create an understanding of cultural currency, as well as the frameworks for analysing how acquiring strong cultural currencies often leads to exchanging them for other strong cultural currencies. Northamptonshire Afro-Caribbean organisations and individuals’ usage of their historical and developed cultural currencies in obtaining greater ethno-racial pride will be illuminated in this article
What I learned? Poetry as history: the multifaceted transitions of a researcher
No full textThis poem was performed and illustrates how the author was shaped, and shaped, his research through this insightful and incisive critical poe
Site 1222
No full textSite 1222 (13°48.98´N, 143°53.35´W; 4989 meters below sea level [mbsl]; Fig. F1) forms a south-central component of the 56-Ma transect drilled during Leg 199 and is situated ~2° south of the Clarion Fracture Zone in typical abyssal hill topography. On the basis of regional magnetic anomalies, we anticipated basement age at Site 1222 to be equivalent to Chron C25r or Chron C25n (~56-57 Ma) (Cande et al., 1989), which is slightly older than at Site 1219. At the outset of drilling at Site 1222, our estimate for total sediment thickness was ~115 m (Fig. F2).
Based upon a fixed hotspot model (Gripp and Gordon, 1990, for 0- to 5-Ma Pacific hotspot rotation pole; Engebretson et al., 1985, for older poles) Site 1222 should have been located ~1° north of the equator at 56 Ma and ~4°N at 40 Ma. A nearby gravity core (EW9709-17GC), taken during the site survey cruise, recovered >5 m of red clay with a late-middle Miocene age on the basis of radiolarian biostratigraphy (Lyle, 2000). Deep Sea Drilling Project (DSDP) Site 42 located ~4° east of Site 1222, was not drilled to basement but contains a thin sedimentary section (~100 m thick) of upper Oligocene nannofossil ooze through middle Eocene radiolarian nannofossil ooze. In turn, DSDP Site 162 lies ~1° north of DSDP Site 42 and is situated on young crust (49 Ma) that contains ~150 m of clayey radiolarian and nannofossil oozes of early Oligocene-middle Eocene age.
Site 1222 will be used to study the position of the Intertropical Convergence Zone in the late Eocene and Oligocene, to sample late Paleocene and early Eocene sediments in the central tropical Pacific Ocean, and to help determine whether or not there has been significant southward movement of the hotspots with respect to the spin axis prior to 40 Ma
Mobile Press-Register sleeve MP0087147
No full textJames Watley, Mobile Press-Register football contest winner / (Mobile Press-Register lobby
DESIGN, SYNTHESIS, AND APPLICATION OF DUAL FUNCTIONING BODIPY PHOTOSENSITIZERS: A THERANOSTIC PHOTODYNAMIC APPROACH FOR CANCER THERAPY
No full textDevelopment of concomitant photodynamic therapy (PDT) and photosensitizer fluorescence detection (PFD), termed theranostics, is of primary interest as combining the two modalities stands to offer a more personalized cost effective “see, treat, and monitor” approach. As a minimally invasive drug-device strategy, the standard protocol involves photosensitizer (light sensitive drug) or fluorophore administration followed by light activation. Specifically, PDT is an approved regimen for the treatment of non-malignant and neoplastic disease. The cytotoxic effect derives from an activated photosensitizer reaction with local oxygen, which produces a tumor damaging species known as singlet oxygen. PFD employs a fluorophore as an invaluable tool for monitoring photosensitizer bio-distribution along with delineating healthy and diseased tissue in the native environment. The two, PDT and PFD, are distinguished via competing photochemical mechanism of administered drugs, which in part hampers their combined application.
A photosensitizer’s therapeutic efficacy is invariably linked to intersystem crossing, which attenuates fluorescence required for imaging. Improving fluorescence yield of photosensitizer’s stands to impart information concerning drug location and concentration. These parameters are vital for determining the optimal time of illumination within PDT. Furthermore, fusion of PDT and PFD enables impromptu eradication of detected disease and subsequent monitoring of photodynamic response when targeted photosensitizers are used.
This dissertation explores the design and synthesis of NIR dual functioning mono-BODIPY photosensitizers for optical image-guided PDT. The synthetic methodology excludes conventional incorporation of halogens as heavy atoms, which alter photophysical properties. Moreover, identification of the key structure photophysical property relationship for obtaining both effective fluorescence and singlet oxygen generation was uncovered along with elucidation of the photochemical mechanism. Above all, application through fluorescence bio-distribution studies and whole body in vivo imaging facilitates more effective tumor ablation through optimizing drug-light intervals for PDT.
The objective of this dissertation is to develop NIR BODIPY photosensitizers applicable for imaging and therapy with one PS. Chapter I describes ingenious efforts to develop NIR BODIPY dyes, yet none have surfaced as dual agents for fluorescence detection and therapy. In addition, Chapter I highlight functionalization of NIR BODIPY dyes for improving water solubility, and tethering to cancer specific biomolecules.
In Chapter II, citing the weak fluorescence of porphyrin based PS and populated triplet state of BODIPY fluorophores, intersystem crossing and production of singlet oxygen was accomplished without the use of heavy halogen atoms such as Br and I. The heavy atom effect significantly reduces the fluorescence, thus limiting its dual-application. BODIPY and thiophene units were fused for extended conjugation with varying electronic effects. An investigation into the structure photophyscial property relationship concluded electron-withdrawing groups enable singlet oxygen generation absent conventional heavy atom incorporation. The lead compound, SBDPiR690 has an inherent brightness and phototoxic power of 26,400 M-1cm-1 and 50,400 M-1cm-1, respectively. The design and synthesis of several analogs resulted in an improved SBDPIR688 analog with a brightness of 37, 440 M-1cm-1 and phototoxic power of 45,120 M-1cm-1.
Chapter III demonstrates the translation of our lead compound SBDPiR690 photo physical properties in vitro and in vivo. Specifically, concentration dependence on cell survival illustrates minimal dark toxicity at the cell monolayer. Furthermore, brightness of the parent compound proved advantageous for non-invasive imaging of bio-distribution. The pharmacokinetic pattern helps establish an optimal drug light interval for vascular-targeted PDT, which was successful in total eradication of sub-cutaneous colon 26 tumor.
In Chapter IV, we modify parent compounds through incorporating functional groups potentially facilitating improved aqueous solubility and overall improved pharmacokinetics. The inclusion of ester moieties through substitution of the boron center disrupts singlet oxygen generation in our improved analog SBDPiR688. However, ester synthons at the peripheral sites of the lead compound SBDPiR690 maintain its therapeutic capability through singlet oxygen generation. The ester functionality offers potential conjugation of target specific ligands for improved pharmacodynamics
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