423 research outputs found
Topics on electron,neutrino and axion scattering
No full textThesis: S.M., Massachusetts Institute of Technology, Department of Physics, 2015.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from PDF version of thesis.Includes bibliographical references (pages 61-64).Under the broad topic of scattering, in this thesis we particularly investigate Lorentz invariance using Compton Scattering at the Compton Polarimeter located in Hall-C at Thomas Jefferson National Accelerator Facility. The Mississippi State Axion Search, an axion search experiment which uses light shining through a wall technique is described in detail, including its instrumentation, initial tests and future impact. Furthermore, a novel method of detection of solar anti-neutrinos based on coherent neutrino scattering is described. Additionally, on the instrumentation side, development of a multi-purpose beam instrument based on synchrotron light to measure the electron beam polarization, beam profile and intensity at the future Electron Ion Collider is presented.by Prajwal Mohanmurthy.S.M
Impact of physical and chemical mutagenesis on growth and flowering parameters in tuberose variety Arka Prajwal
No full textThe present study evaluated the effects of physical (gamma radiation) and chemical (ethyl methane sulphonate, EMS) mutagens on the growth and flowering parameters of Arka Prajwal in the M1V1 generation. Uniform-sized bulbs were subjected to gamma radiation (1.5 kR, 2.0 kR and 2.5 kR) and EMS treatments (0.3%, 0.4% and 0.5%) to induce variability. Growth parameters, including sprouting time, plant height, number of leaves, leaf dimensions and plant spread, exhibited significant variation across treatments. Gamma radiation delayed bulb sprouting (21.27–25.83 days) compared to control (12.53 days), while EMS treatments showed intermediate sprouting times (14.75–20.13 days). Plant height and leaf dimensions were highest in 0.4% EMS-treated plants, with notable increases in leaf width and plant spread. Flowering parameters demonstrated that EMS treatments accelerated spike emergence and floret opening compared to gamma irradiation. EMS-treated plants (0.3%) showed the earliest flowering, with reduced days to spike emergence (73.47 days) and first floret opening (90.38 days). Spike length and rachis length were slightly reduced in gamma-treated plants, while EMS-treated plants maintained longer spikes and rachis. The number of florets per spike was highest under EMS treatment (44.93 florets for 0.3%), accompanied by improved floret dimensions and weight. The study highlights that EMS enhanced growth and flowering performance in Arka Prajwal, while higher doses of gamma radiation adversely affected these parameters. This research provides insights into the potential of mutagenesis for improving floricultural traits in tuberose
Widespread Aggregation and Neurodegenerative Diseases Are Associated with Supersaturated Proteins
No full textSummaryThe maintenance of protein solubility is a fundamental aspect of cellular homeostasis because protein aggregation is associated with a wide variety of human diseases. Numerous proteins unrelated in sequence and structure, however, can misfold and aggregate, and widespread aggregation can occur in living systems under stress or aging. A crucial question in this context is why only certain proteins appear to aggregate readily in vivo, whereas others do not. We identify here the proteins most vulnerable to aggregation as those whose cellular concentrations are high relative to their solubilities. We find that these supersaturated proteins represent a metastable subproteome involved in pathological aggregation during stress and aging and are overrepresented in biochemical processes associated with neurodegenerative disorders. Consequently, such cellular processes become dysfunctional when the ability to keep intrinsically supersaturated proteins soluble is compromised. Thus, the simultaneous analysis of abundance and solubility can rationalize the diverse cellular pathologies linked to neurodegenerative diseases and aging
MDO framework for university research collaboration: AGILE academy initiatives & outcomes
Get PDFAGILE Project is developing the 3rd generation MDO processes, which will support the development of the next generation aerospace products. The establishment of effective collaborative design methodologies is currently acknowledged as the key enabler for future product development processes. At the same time, the need to introduce collaborative design techniques within educational activities is also well recognized by the Academic, Research and Industrial communities. AGILE project supported by European Commission’s H2020 Programme, is setting the “AGILE Paradigm”, a conceptual framework which contains all the elements to implement a multidisciplinary collaborative design network. The AGILE Academy initiative is conceived to infuse into the Academic organizations and educational environments the “AGILE Paradigm”, and make available all the technologies developed within the AGILE Project, which support the implementation of such a Paradigm. This paper focus is on the inception, approach and results of the AGILE Academy participants from several universities around the world
Supersaturated proteins are enriched at synapses and underlie cell and tissue vulnerability in Alzheimer's disease
No full textsj-docx-1-rpo-10.1177_11795727221126070 – Supplemental material for TEleRehabilitation Nepal (TERN) for People With Spinal Cord Injury and Acquired Brain Injury: A Feasibility Study
No full textSupplemental material, sj-docx-1-rpo-10.1177_11795727221126070 for TEleRehabilitation Nepal (TERN) for People With Spinal Cord Injury and Acquired Brain Injury: A Feasibility Study by Raju Dhakal, Mandira Baniya, Rosie M Solomon, Chanda Rana, Prajwal Ghimire, Ram Hariharan, Sophie G Makower, Wei Meng, Stephen Halpin, Sheng Quan Xie, Rory J O’Connor, Matthew J Allsop and Manoj Sivan in Rehabilitation Process and Outcome</p
sj-docx-2-rpo-10.1177_11795727221126070 – Supplemental material for TEleRehabilitation Nepal (TERN) for People With Spinal Cord Injury and Acquired Brain Injury: A Feasibility Study
No full textSupplemental material, sj-docx-2-rpo-10.1177_11795727221126070 for TEleRehabilitation Nepal (TERN) for People With Spinal Cord Injury and Acquired Brain Injury: A Feasibility Study by Raju Dhakal, Mandira Baniya, Rosie M Solomon, Chanda Rana, Prajwal Ghimire, Ram Hariharan, Sophie G Makower, Wei Meng, Stephen Halpin, Sheng Quan Xie, Rory J O’Connor, Matthew J Allsop and Manoj Sivan in Rehabilitation Process and Outcome</p
Determining the Effect of Integrated Nutrient Management (INM) on Growth and Flower Yield of Tuberose (Polianthes tuberosa L.) cv. Prajwal
No full textTuberose (Polyanthes tuberosa L.) is a highly valued commercial bulbous ornamental plant found in tropical and subtropical climates in the Amaryllidaceae family. It is high demand in both domestic and distant markets due to its long tepels, funnel shape, and strong fragrance. The field experiment was carried out to study the effect of integrated nutrient management on growth and flower yield of tuberose cv. Prajwal during the year of 2021 -2022 at Department of Horticulture, Annamalai University, Annamalainagar, Tamil Nadu. The investigation was laid out in Randomized Block Design with 10 treatments and replicated thrice. The treatments comprised of different levels of FYM (25% and 15%), poultry manure (25% and 15%), vermicompost (25 % and 15 %), inoculation of Azotobacter (2 kg ha-1) and phosphate solubilizing bacteria (2 kg ha-1) along with RDF (100 % and 75 %). Among the different treatments, T10 (75 % RDF + Azotobacter @ 2 kg ha-1 + PSB @ 2 kg ha-1) was discovered to be more successful in improving all growth, physiological and flowering characters viz., plant height (51.75 cm), number of side shoots plant-1 (11.23), leaf area (98.76 cm2), chlorophyll content (0.99 mg g-1), dry matter production (42.37 g plant-1) and flowering and yield parameter viz., number of spike plant-1 (3.12), length of spike (105.30 cm), number of florets spike-1 (56.11) and flower yield ha-1 (15.72 t ha‑1)
Influence of Parametric Modelling of Wing Subsystems on the Aircraft Design and Performance
No full textAircraft design methodologies have been significantly developing from the past few years with the advancements in knowledge based techniques. These methods enable the storage of design knowledge and rules, and reuse them to create different types of designs, thus preventing the designer to perform repetitive tasks. Tasks such as parametric modelling of components, such as the aircraft wing can be automated by storing the modelling processes and the design rules in a knowledge base. With this process, variants of the wing with different geometric parameters can then be generated in a short duration by simply varying certain top-level requirements. It is necessary to extend these design techniques to model aircraft systems in the conceptual design stage. This, not only decreases the time of design realisation but also presents a scope to assess the effects of various inter-dependencies due to systems and make appropriate changes, in the early stages of aircraft design. Developing and demonstrating a framework which aids to assess the influence of the wing subsystems, namely the flight control actuators, fuel tanks and anti-ice elements; on the aircraft design and performance in the conceptual design stage is the aim of the thesis. This thesis presents a combination of physics based and knowledge based design methodologies to size the wing subsystems and position them in the airframe. Consequently, the methods are integrated into the conceptual aircraft design process to enable multidisciplinary design with supporting domains. The methods are aimed to aid the design of conventional systems architectures and More Electric Aircraft (MEA) systems architectures as well. With these methodologies, the Systems Model Generator (SMG) application is developed in Python to facilitate semi-automatic wing subsystems sizing and orientation in the airframe based on top-level aircraft requirements, initial aircraft design parameters and system specific parameters. The subsystem models generated with the proposed methodology for short-medium range civil transport aircraft are verified and validated as well. Knowledge based systems and subsystems selection are implemented to facilitate semi-automated systems, subsystems and architecture selection, based on the aircraft configuration and systems specific requirements. Methods for automatic iterative fuel tanks sizing and intersection detection are implemented to further reduce the overall design time and make the tool more suitable for integrated sizing.With the multidisciplinary design framework, the conceptual parametric models, volume, mass, power consumption and position of the subsystems in the airframe are generated and propagated in the conceptual aircraft design stage; thus bridging the conceptual and the preliminary design stages. In the proposed framework, the domains of aircraft design generation, systems selection and sizing, subsystems selection and sizing, engine sizing and mission simulation are considered for the multidisciplinary design process. The domains are integrated with the DLR CPACS-RCE framework. A case study to demonstrate the process of integrated parametric subsystems sizing of the aircraft, with the proposed framework is presented. The aim of this case study is to assess the influence of the MEA systems architecture relative to the conventional systems architecture for a short-medium range transport aircraft, similar to the Airbus A320-200. In this case study, the quantitative influence of the subsystems' parameters on the aircraft design and performance parameters is determined and analysed. The subsystems' parameters constitute the mass, power consumption, volume and location of the subsystems in the airframe and the aircraft design parameters constitute the aircraft masses such as the overall empty mass and the fuel mass for the mission. The generation and propagation of the design and performance parameters of the aircraft through each domain of the framework are presented and analysed as well with the case study. In this case study, it is observed that the MEA systems architecture results in a lower mission fuel mass relative to the conventional systems architecture by nearly 2.3\%. Furthermore, these results are compared with literature and observed to be in the similar range of 2-7\%. Thus, the validated aircraft design framework presented in this thesis enables to substantially increases and propagate the design knowledge of aircraft systems, in the early design stages.AGILEAerospace Engineerin
Low-cost uni-directional PFC for 3-phase systems
No full textPower consumed by any equipment connected to the grid must be regulated to facilitate the reliable and efficient operation of the grid and for smooth equipment operation of other consumers. Power factor is one of the major power quality measurement tool. All the electrical equipment connected to the grid must comply with the power factor limits as specified under various standards. This thesis aims at the development of a cost-effective power factor correction converter for a motor drive with a power range up to 10 kW, which is also robust for line and load transients.Electrical Engineerin
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