1,285 research outputs found

    Lyons, Ronan

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    Understanding flucloxacillin prescribing trends and treatment non-response in UK primary care: a Clinical Practice Research Datalink (CPRD) study

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    The volume of prescribed antibiotics is associated with antimicrobial resistance and, unlike most other antibiotic classes, flucloxacillin prescribing has increased. We aimed to describe UK primary care flucloxacillin prescribing and factors associated with subsequent antibiotic prescribing as a proxy for non-response.Clinical Practice Research Datalink patients with acute prescriptions for oral flucloxacillin between January 2004 and December 2013, prescription details, associated Read codes and patient demographics were identified. Monthly prescribing rates were plotted and logistic regression identified factors associated with having a subsequent antibiotic prescription within 28 days.3 031 179 acute prescriptions for 1 667 431 patients were included. Average monthly prescription rates increased from 4.74 prescriptions per 1000 patient-months in 2004 to 5.74 (increase of 21.1%) in 2013. The highest prescribing rates and the largest increases in rates were seen in older adults (70+ years), but the overall increase in prescribing was not accounted for by an ageing population. Prescribing 500 mg tablets/capsules rather than 250 mg became more common. Children were frequently prescribed low doses and small volumes (5 day course) and prescribing declined for children, including for impetigo. Only 4.2% of new prescriptions involved co-prescription of another antibiotic. Age (<5 and ≥60 years), diagnosis of 'cellulitis or abscess' or no associated code, and 500 mg dose were associated with a subsequent antibiotic prescription, which occurred after 17.6% of first prescriptions.There is a need to understand better the reasons for increased prescribing of flucloxacillin in primary care, optimal dosing (and the need to co-prescribe other antibiotics) and the reasons why one in five patients are prescribed a further antibiotic within 4 weeks

    Grandchildren of the revolution : sexuality, nation and Frank Ronan

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    Mestrado em Estudos InglesesEsta tese propõe-se a investigar expressões do discurso gay irlandês contemporâneo na obra do autor irlandês Frank Ronan. O tratamento literário de temas como a influência da Igreja Católica, a importância da célula familiar irlandesa, ou a manifestação de posições políticas relacionadas com nacionalismo e colonialismo nas suas obras será analisado, com vista a examinar como estes e outros factores moldam a maneira como o discurso homossexual é construído na república da Irlanda e no trabalho de Frank Ronan em particular. Também será dada atenção a estereótipos nacionais e o seu efeito na escrita de Frank Ronan. ABSTRACT: This dissertation proposes an investigation of expressions of the contemporary Irish gay discourse in the fiction of Irish author Frank Ronan. The literary treatment of themes such as the influence of the Catholic Church, the importance of the Irish family cell, or the manifestation of political views, concerning nationalism and colonialism in the novels will be analysed, in order to study how these and other factors shape the way that homosexual discourse is constructed in the Republic of Ireland and in the work of Frank Ronan in particular. Attention will also be given to Irish national stereotypes, and their effect on Ronan’s writing

    sj-pdf-1-jrs-10.1177_01410768221107119 - Supplemental material for SARS-CoV-2 infection risk among 77,587 healthcare workers: a national observational longitudinal cohort study in Wales, United Kingdom, April to November 2020

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    Supplemental material, sj-pdf-1-jrs-10.1177_01410768221107119 for SARS-CoV-2 infection risk among 77,587 healthcare workers: a national observational longitudinal cohort study in Wales, United Kingdom, April to November 2020 by Joe Hollinghurst, Laura North, Tamas Szakmany, Richard Pugh, Gwyneth A Davies, Shanya Sivakumaran, Rebecca Jarvis, Martin Rolles, W Owen Pickrell, Ashley Akbari, Gareth Davies, Rowena Griffiths, Jane Lyons, Fatemeh Torabi, Richard Fry, Mike B Gravenor and Ronan A Lyons in Journal of the Royal Society of Medicine</p

    sj-pdf-2-jrs-10.1177_01410768221107119 - Supplemental material for SARS-CoV-2 infection risk among 77,587 healthcare workers: a national observational longitudinal cohort study in Wales, United Kingdom, April to November 2020

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    Supplemental material, sj-pdf-2-jrs-10.1177_01410768221107119 for SARS-CoV-2 infection risk among 77,587 healthcare workers: a national observational longitudinal cohort study in Wales, United Kingdom, April to November 2020 by Joe Hollinghurst, Laura North, Tamas Szakmany, Richard Pugh, Gwyneth A Davies, Shanya Sivakumaran, Rebecca Jarvis, Martin Rolles, W Owen Pickrell, Ashley Akbari, Gareth Davies, Rowena Griffiths, Jane Lyons, Fatemeh Torabi, Richard Fry, Mike B Gravenor and Ronan A Lyons in Journal of the Royal Society of Medicine</p

    Children and Disasters: A tribute to Professor Kevin Ronan

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    (c) The Author/sIn 1997, Professor Kevin Ronan published a paper in the first ever edition of the Australasian Journal of Disaster and Trauma Studies, titled “The Effects of a “Benign” Disaster: Symptoms of Post-traumatic Stress in Children Following a Series of Volcanic Eruptions”. Over the next 23 years, Kevin and his many colleagues pursued aspects of children and disasters to both improve practice and advance scholarship in this area. In March 2020 we were saddened by the untimely passing of Kevin. As a tribute to Professor Ronan this special issue of the Australasian Journal of Disaster and Trauma Studies brings together accounts of current research and practice initiatives inspired by, building upon, and directly influenced by Professor Ronan’s work

    Prof Ronan Lyons

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    SAIL dementia e-cohort (SAIL-DeC)

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    These files contain details on the creation of the Secure Anonymised Information Linkage (SAIL) databank dementia e-cohort (SAIL-DeC).Wilkinson, Tim; Schnier, Christian; Akbari, Ashley; Orton, Chris; Sleegers, Kristel; Gallacher, John; Lyons, Ronan A; Sudlow, Cathie LM. (2019). SAIL dementia e-cohort (SAIL-DeC), [dataset]. University of Edinburgh. Usher Institute of Population Health Sciences and Informatics. https://doi.org/10.7488/ds/250

    Privilege and Property. Essays on the History of Copyright

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    Copyright law is the site of significant contemporary controversy. In recent years copyright history has transformed as a subject from being one of interest to a few books historians to the focus of sustained historical investigation attracting the attention of scholars from across the humanities. This book comprises a collection of essays on copyright history by leading experts drawn from a range of countries and disciplinary perspectives. Covering the period from 1450 to 1900, these essays engage with a number of related themes. The first considers the general movement, from the sixteenth century onwards, from privilege to property-based conceptions of copyright protection. The second addresses the relationship between the protection provided for literary and print materials and that provided for other forms of cultural production. The third concerns the significance and relevance of these various histories in shaping and informing contemporary policy and academic practice. Essays include: 0. The History of Copyright History, by Kretschmer, Deazley & Bently; 1. From Gunpowder to Print: The Common Origins of Copyright and Patent, by Joanna Kostylo; 2. A Mongrel of early modern copyright: Scotland in European Persepctive, by Alastair Mann; 3. The Public Sphere and the Emergence of Copyright: Areopagitica, the Stationers’ Company, and the Statute of Anne, by Mark Rose; 4. Early American Printing Privileges: the Ambivalent Origins of Authors’ Copyright in America, by Oren Bracha; 5. Author and Work in the French Print Privileges System: Some Milestones, by Laurent Pfister; 6. A Venetian Experiment on Perpetual Copyright, by Maurizio Borghi; 7. Les formalités son mortes, vive les formalities! Copyright formalities in nineteenth century Europe, by Stef van Gompel; 8. The Berlin Publisher Friedrich Nicolai and the reprinting sections of the Prussian Statute Book of 1794, by Friedemann Kawohl; 9. Nineteenth Century Controversies relating to the protection of Artistic Property in France, by Frédéric Rideau; 10. Maps, Views and Ornament. Visualising Property in Art and Law: The Case of pre-modern France, by Katie Scott; 11. Breaking the Mould? The Radical Nature of the Fine Art Copyright Bill 1862, by Ronan Deazley; 12. ‘Neither bolt nor chain, iron safe nor private watchman, can prevent the theft of words’: The birth of the performing right in Britain, by Isabella Alexander; 13. The Return of the Commons: Copyright History as a Common Source, by Karl-Nikolaus Peifer; 14. The Significance of Copyright History for the Publishing History and Historians, by John Feather; 15. Metaphors of Intellectual Property, by William St Clair. The volume is a companion to the digital archive Primary Sources on Copyright (1450-1900), funded by the UK Arts and Humanities Research Council (AHRC): www.copyrighthistory.or

    sj-pdf-1-jrs-10.1177_01410768231181268 - Supplemental material for Trends in SARS-CoV-2 infection and vaccination in school staff, students and their household members from 2020 to 2022 in Wales, UK: an electronic cohort study

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    Supplemental material, sj-pdf-1-jrs-10.1177_01410768231181268 for Trends in SARS-CoV-2 infection and vaccination in school staff, students and their household members from 2020 to 2022 in Wales, UK: an electronic cohort study by Emily Lowthian, Hoda Abbasizanjani, Stuart Bedston, Ashley Akbari, Laura Cowley, Richard Fry, Rhiannon K Owen, Joe Hollinghurst, Igor Rudan, Jillian Beggs, Emily Marchant, Fatemeh Torabi, Simon de Lusignan, Tom Crick, Graham Moore, Sheikh Aziz Ronan A Lyons in Journal of the Royal Society of Medicine</p
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