16 research outputs found
Casting Fu Manchu by Eelyn Lee [performance review]
No full textIn lieu of an abstract, here is a brief excerpt of the content:
Reviewed by: Tobi Poster-Su
CASTING FU MANCHU. By Eelyn Lee. Chinese Arts Now Digital Commission, UK. Streamed, December 1, 2020.
Dr. Fu Manchu, the archetypal supervillain invented by English author Sax Rohmer in the 1910s and featured in countless Hollywood portrayals from the 1920s to the 2000s, has been described by scholars such as Ruth Mayer as the embodiment of Yellow Peril, an ideological construction of East Asia that William F. Wu regards as so pervasive within Western culture as to fundamentally shape both public perception and political policy.
Perhaps fittingly, Fu Manchu has not been portrayed in any major film production by a Chinese or East Asian performer. Instead, the character has been portrayed by white men engaging in makeup-assisted racial mimicry (a practice explored in David Henry Hwang’s 2007 play Yellow Face). This fact formed the backdrop for Eelyn Lee’s digital short, Casting Fu Manchu, for which Lee invited East and Southeast Asian performers to submit audition self-tapes of sides taken directly from classical Hollywood films featuring the character. These self-tapes, which featured prominently within the performance itself, created an opportunity for performers to subvert and reappropriate a character whose legacy can be seen as directly connected to the current resurgence in anti-Chinese sentiment
The VaCo Mould, a research about a new moulding principle for double curved concrete panels
No full textCurrent issues around the pharmacotherapy of ADHD in children and adults
No full textBackground New drugs and new formulations enter the growing market for ADHD medication. The growing awareness of possible persistence of ADHD impairment beyond childhood and adolescence resulting in increased pharmacotherapy of ADHD in adults, is also a good reason for making an inventory of the what is generally known about pharmacotherapy in ADHD. Aim To discuss current issues in the possible pharmacotherapy treatment of ADHD in children, adolescents and adults with respect to the position of pharmacotherapy in ADHD treatment guidelines, the pharmacoepidemiological trends, and current concerns about the drugs used. Methods A search of the literature with an emphasis on the position of pharmacotherapy in ADHD treatment guidelines, the pharmacoepidemiological trends, and current concerns about the drugs used in pharmacotherapy. Results According to the guidelines, the treatment of ADHD in children consists of psychosocial interventions in combination with pharmacotherapy when needed. Stimulants are the first-choice drugs in the pharmacological treatment of ADHD in children despite a number of well known and frequently reported side effects like sleep disorders and loss of appetite. With regard to the treatment of adults, stimulant treatment was recommended as the first-choice pharmacotherapy in the single guideline available. Both in children and adults, there appears to be an additional though limited role for the nonadrenergic drug atomoxetine. The increase of ADHD medication use, in children, adolescents and in adults, can not only be interpreted as a sign of overdiagnosis of ADHD. Despite the frequent use of stimulants, there is still a lack of clarity on the effects of long-term use on growth and nutritional status of children. Cardiovascular effects of both stimulants and atomoxetine are rare but can be severe. The literature suggests that atomoxetine may be associated with suicidal ideation in children. Conclusion Although pharmacotherapy is increasing common in the treatment of ADHD in both children and adults, there are still a lot of questions about side effects and how best to counter them. This suggests an important role for close monitoring of children and adults treated with stimulants or atomoxetin
Measuring occupation span at two stone circle sites in Larimer County, Colorado
No full text2017 Spring.Includes bibliographical references.Stone circle sites are notorious for low artifact frequencies. This deters archaeological study because low artifact frequencies are thought to limit research potential. Two stone circle sites, Killdeer Canyon (5LR289) and T-W Diamond (5LR200) offer insight into short-term habitations, despite their low artifact frequencies. The two sites are located in northern Colorado, in the hogback zone along the Front Range of the Southern Rocky Mountains. The Colorado State University field school excavated the sites in 1982 and 1971 respectively. Artifacts from the interior of the features include lithic tools and debris, bone, and ceramics. This thesis examines each artifact class from excavated context as a proxy for understanding the length and number of occupations. Local and non-local chipped stone ratios, faunal procurement and processing strategies, and petrographic analysis are used to address how long and how many times each site was occupied. New radiocarbon dates show contemporaneity between rings at each site, dating Killdeer Canyon to the late A.D. 1600s and T-W Diamond to the late A.D. 1200s. These data demonstrate the ephemerality of the two sites but highlight potential differences in site use. While Killdeer Canyon likely represents a small group passing through an area, T-W Diamond could represent a larger group congregation, perhaps for hunting purposes. Furthermore, this thesis attests to the merit of using multiple lines of evidence to compensate for small sample sizes
DNA methylation patterns in cord blood DNA and body size in childhood.
No full textThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.BACKGROUND: Epigenetic markings acquired in early life may have phenotypic consequences later in development through their role in transcriptional regulation with relevance to the developmental origins of diseases including obesity. The goal of this study was to investigate whether DNA methylation levels at birth are associated with body size later in childhood. PRINCIPAL FINDINGS: A study design involving two birth cohorts was used to conduct transcription profiling followed by DNA methylation analysis in peripheral blood. Gene expression analysis was undertaken in 24 individuals whose biological samples and clinical data were collected at a mean ± standard deviation (SD) age of 12.35 (0.95) years, the upper and lower tertiles of body mass index (BMI) were compared with a mean (SD) BMI difference of 9.86 (2.37) kg/m(2). This generated a panel of differentially expressed genes for DNA methylation analysis which was then undertaken in cord blood DNA in 178 individuals with body composition data prospectively collected at a mean (SD) age of 9.83 (0.23) years. Twenty-nine differentially expressed genes (>1.2-fold and p<10(-4)) were analysed to determine DNA methylation levels at 1-3 sites per gene. Five genes were unmethylated and DNA methylation in the remaining 24 genes was analysed using linear regression with bootstrapping. Methylation in 9 of the 24 (37.5%) genes studied was associated with at least one index of body composition (BMI, fat mass, lean mass, height) at age 9 years, although only one of these associations remained after correction for multiple testing (ALPL with height, p(Corrected) = 0.017). CONCLUSIONS: DNA methylation patterns in cord blood show some association with altered gene expression, body size and composition in childhood. The observed relationship is correlative and despite suggestion of a mechanistic epigenetic link between in utero life and later phenotype, further investigation is required to establish causality
Returning culture to peacebuilding : contesting the liberal peace in Sierra Leone
No full textThis thesis investigates the advantages and limitations of applying culture to the analysis of violent conflict and peacebuilding, with a particular focus on liberal peacebuilding in Sierra Leone. While fully aware of the critique of the concept of culture in terms of its uses for the production of difference and ‘otherness,’ it also seeks to respond to the critique of liberal peacebuilding on the account of its low sensitivity towards local culture, which allegedly undermines the peace effort. After a careful examination of the terms of discussion about culture enabled by theoretical approaches to conflict in Chapter 2, the thesis presents a theoretical framework for the analysis of cultural aspects of conflict and peace based on the processes and effects of meaning-generation (Chapter 3), developing the conceptual apparatus and vocabulary for the subsequent empirical study. Instead of bracketing out the recursive nature of cultural theorising, the developed approach embraces the recursive dynamics which arise as a result of cultural ‘embeddedness’ of the analyst and the processes which s/he seeks to elucidate, mirroring similar dynamics in the cultural production of meaning and knowledge. The framework of ‘embedded cultural enquiry’ is then used to analyse the practices of liberal peacebuilding as a particular culture, which shapes the interaction of the liberal peace with its ‘subjects’ and critics as well as framing its reception of the cultural problematic generally (Chapter 4). The application of the analytical framework to the case study investigates the interaction between the liberal peace and ‘local culture,’ offering an alternative reading of the conflict and peace process in Sierra Leone (Chapter 5). The study concludes that a greater attention to cultural meaning-making offers a largely untapped potential for peacebuilding, although any decisions with regard to its deployment will inevitably be made from within an inherently biased cultural perspective
Atlantic salmon farms are a likely source of Tenacibaculum maritimum infection in migratory Fraser River sockeye salmon
No full textJuvenile sockeye salmon in British Columbia migrate past numerous Atlantic salmon farms from which they may acquire infectious agents. We analyse patterns of molecular detection in juvenile sockeye for the bacterium Tenacibaculum maritimum, known to cause disease in fish globally and to cause mouthrot disease in farmed Atlantic salmon in BC. Our data show a clear peak in T. maritimum detections in the Discovery Islands region of BC, where sockeye migrate close to salmon farms. Using well established differential-equation models to describe sockeye migration and bacterial infection, fit to detection data, we assessed support for multiple hypotheses describing farm- and background-origin infection. Our best models (with 99.8% empirical support) describe constant background infection pressure, except around Discovery-Islands salmon farms, where farm-origin infection pressure peaked at 12.7 (approximate 95% CI: 4.5 to 31) times background levels. Given the severity of associated disease in related species and the imperilled nature of Fraser River sockeye, our results suggest the need for a more precautionary approach to managing farm/wild interactions in sockeye salmon.The presentation of the authors' names and (or) special characters in the title of the pdf file of the accepted manuscript may differ slightly from what is displayed on the item page. The information in the pdf file of the accepted manuscript reflects the original submission by the author
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Fetal Origins, Childhood Development, and Famine: A Bibliography and Literature Review
No full textThe human costs of famines outlast the famines themselves. An increasing body of research points to their adverse long-run consequences for those born or in utero during them. This paper offers an introduction to the burgeoning literature on fetal origins and famine through a review of research on one well-known case study and a bibliography of published work in the field generally.health, famine, fetal origins, economic history
Multivariate methods in aquaculture research: case studies of tilapias in experimental and commercial systems
No full textThis volume documents the usefulness of multivariate methods û notably multiple regression, path analysis and canonical correlation û in the context of aquaculture, which has to date tended to neglect such methods, and hence to underutilize available data. All examples used here stem from experimental and/or commercial tilapia culture systems, and hence this book also represents an advance in the understanding of such systems.Aquaculture, Tilapia culture, Growth, Multivariate analysis Oreochromis
