726 research outputs found
Management of refractory angina: An update
No full textDespite the use of anti-Anginal drugs and/or percutaneous coronary interventions (PCI) or coronary artery bypass grafting, the proportion of patients with coronary artery disease who have daily or weekly angina ranges from 2% to 24%. Refractory angina refers to long-lasting symptoms (for >3 months) due to established reversible ischaemia, which cannot be controlled by escalating medical therapy with the use of 2nd-And 3rd-line pharmacological agents, bypass grafting, or stenting. While there is uncertain prognostic benefit, the treatment of refractory angina is important to improve the quality of life of the patients affected. This review focuses on conventional pharmacological approaches to treating refractory angina, including guideline directed drug combination and dosages. The symptomatic and prognostic impact of advanced and novel revascularization strategies such as chronic total occlusion PCI, transmyocardial laser revascularization, coronary sinus occlusion, radiation therapy for recurrent restenosis, and spinal cord stimulation are also covered and recommendations of the 2019 ESC Guidelines on the Diagnosis and Management of Chronic Coronary Syndromes discussed. Finally, the potential clinical use of current angiogenetic and stem cell therapies in reducing ischaemia and/or pain is evaluated
Correction to : Cost-Effectiveness of Parent–Child Interaction Therapy in Clinics versus Homes : Client, Provider, Administrator, and Overall Perspectives (Journal of Child and Family Studies, (2018), 27, 10, (3329-3344), 10.1007/s10826-018-1159-4)
No full textThe original version of this article unfortunately contained a mistake. The Author contributions section currently states: “A.F.: designed and conducted data analyses for this study, supervised by B.Y. with input by T.F. A.F. and T.F. assisted B.Y. in writing and revising the manuscript.” In fact, B.Y. and T.F. assisted A.F. in writing and revising the manuscript. Although T.F. and B.Y. were both involved in the writing, primary credit should go to A.F. (Alexis French, the first author). The authorship order above is accurate.</p
Review of the Monograph T.F. Khaidarov “Age of ‘Black Death’ in Golden Horde and Adjacent Regions” Kazan: Marjani Institute of History of Academy of Sciences, 2018. 304 P.
No full textThe author examines the monographic work of T.F. Khaidarov, devoted to the study of the second plague pandemic in the Golden Horde and neighboring territories, which was published in 2018. Researchers have already studied some aspects of the course of the Black Death in Eastern Europe. Before the publication of the monograph, T.F. Khaidarov had published several articles devoted to this problem. Despite this, the monograph is the first experience of a comprehensive study of the manifestations of the second plague pandemic in all their diversity in Eastern Europe. The objectives set in the book required the synthesis of various natural sciences (biology, climatology, medicine) and social (history, historical source study, social anthropology) disciplines. In the monograph phenomena of different scale are investigated. On the one hand, the epidemics in Eastern Europe were considered in the context of the worldwide course of the pandemic. On the other hand, from the researcher’s view did not escape the local phenomena: the specific dating of a particular outbreak of the epidemic, the problem of the perception of the disease by society, the features of its description, etc. In the review, an assessment is given to this "total" study of the pandemic. The advantage of this approach is that it overcomes the boundaries between different scientific disciplines, allows us to fill the knowledge that is fragmentary in each separate science. The drawback of this approach is that it leads to the absolutization of the plague factor in history. The study of Black Death becomes the main link in the whole multidisciplinary research, turns into a kind of paradigm. Sometimes this leads to incorrect reading of historical sources and scientific works. Despite the revealed shortcomings, it should be recognized that the monograph of T.F. Khaidarov is a serious step forward in the study of the problem at the present stage of the development of science
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No full textElectrical Engineering, Mathematics and Computer Scienc
Fabrieksschema van de bereiding van styreen
No full textDocument(en) uit de collectie Chemische ProcestechnologieDelftChemTechApplied Science
Диагностика кист почек при скрининговом ультразвуковом исследовании больных с артериальной гипертензией и особенности выявления у этих пациентов признаков малигнизации сложных кистозных образований
No full textКисты почек диагностируют часто. Так, по данным T.F. Luscher и соавторов, у 1/3 пациентов в возрасте 50 лет и старше обнаруживаются кисты почек разных размеров. Факт связи кист почек с артериальной гипертензией ни у кого не вызывает сомнения. В литературе приведено много данных о снижении артериального давления и нормализации ренина плазмы крови после опорожнения кист. Широкое применением в медицинской практике ультразвукового метода для скринингового исследования органов брюшной полости позволило значительно чаще выявлять простые солитарные кисты и сложные кистозные образования почек. При этом 5–7% сложных кистозных образований почек невозможно достоверно дифференцировать с помощью традиционных УЗИ и КТ-методов визуализации. Вместе с тем, злокачественный процесс в сложных кистах, по данным различных авторов, составляет от 0,1% до 10%. Цель исследования: повысить эффективность диагностики кист почек путем сринингового УЗИ больных с артериальной гипертензией и дополнительным применением у пациентов со сложными кистозными образованиями современных методов дифференциальной диагностики для подтверждения (исключения) их малигнизации
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