1,721,221 research outputs found
Prognostic tools for older patients with DLBCL: complex patients require complex solutions and a personal touch
Full text linkPrognosis of follicular lymphomas
No full textFollicular lymphoma (FL) is as an indolent neoplasia with median survival measured in decades. Nevertheless, some patients have poor progression-free survival and overall survival. Several treatment approaches are proposed for patients with FL, however criteria to rationalize treatment decisions are lacking. Studies have been performed to build up prognostic indices that are useful for defining risk-adapted treatment recommendations. Available indices are based on parameters that have an independent role in predicting patient survival and that are variably correlated with the features of the disease, with the characteristics of the patient and with the effects of treatment. Two new prognostic indices have recently been proposed for FL: the Italian Lymphoma Intergroup (ILI) index and the Follicular Lymphoma International prognostic Index (FLIPI). Both indices are based on large series of patients and exhibit differences in their ability to discriminate between patients with different probabilities of survival. In recent years, with the advent of gene expression profile studies, our knowledge of the biology of FL is changing as novel data become available about the lymphoma cell and about the role of the microenvironment; these studies have already provided novel prognostic tools for identifying patients with more aggressive disease. Further data and large international cooperative studies are needed to translate into clinical practice the novel acquisitions of biology and therapeutics. Copyrigh
The role of anthracyclines in follicular lymphomas
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Do we need high-dose therapy for initial treatment of high-risk Hodgkin's disease? Venezia New isights in Hematology
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Positron emission tomography-computed tomography in follicular lymphoma: "One fit for all"?
No full textEditorial article on the role of FDG PET in patients with Follicular Lymphom
Serum MUC-1 as a marker of disease status in multiple myeloma patients receiving thalidomide - Response to Mileshkin et al.
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