478 research outputs found
Records of Travels in Turkey, Greece etc. and of a cruise in the Black Sea, with the capitan Pacha, in the years 1829, 1830, and 1831. By Adolphus Slade, Esq. in two volumes. London Saunders and otley, Conduit street 1832
No full textPreface: by the authorDedication: by the author to his royal Highness the ... of CumberlandContent description: Detailed contentsIllustration: 2 (Maps ,Views ,)Pagination: PP13+513P, PP6+511PVolumes: 2Edition:1stText Genre:ProseIllustration: 2 (χάρτες ,τοπία ,
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Written evidence submitted by Professor Karen Slade (RAR0071) to Rehabilitation and resettlement: ending the cycle of reoffending (Inquiry)
No full textThis submission focuses specifically on sections 2 and 3 of the inquiry terms of reference and is based on research and practice expertise from the author. Karen Slade is a Professor of applied forensic psychology and a Forensic Psychologist at Nottingham Trent University (NTU). She is currently on secondment with HMPPS, and this submission is written in a personal capacity based on her academic research. This submission makes four recommendations to questions related to section two and five related to section three. This submission focuses on the concept of dual harm and mortality recording, prevention and support within the custodial estate and beyond
Hydrogen sulfide supplementation as a potential treatment for primary mitochondrial diseases
No full textPrimary mitochondrial diseases (PMD) are amongst the most common inborn errors of metabolism causing fatal outcomes within the first decade of life. With marked heterogeneity in both inheritance patterns and physiological manifestations, these conditions present distinct challenges for targeted drug therapy, where effective therapeutic countermeasures remain elusive within the clinic. Hydrogen sulfide (H2S)-based therapeutics may offer a new option for patient treatment, having been proposed as a conserved mitochondrial substrate and post-translational regulator across species, displaying therapeutic effects in age-related mitochondrial dysfunction and neurodegenerative models of mitochondrial disease. H2S can stimulate mitochondrial respiration at sites downstream of common PMD-defective subunits, augmenting energy production, mitochondrial function and reducing cell death. Here, we highlight the primary signalling mechanisms of H2S in mitochondria relevant for PMD and outline key cytoprotective proteins/pathways amenable to post-translational restoration via H2S-mediated persulfidation. The mechanisms proposed here, combined with the advent of potent mitochondria-targeted sulfide delivery molecules, could provide a framework for H2S as a countermeasure for PMD disease progression.</p
The Gothic Elements of David Mitchell's Slade House
No full textThis thesis introduces the tradition of the English Gothic novel and defines the basic themes, motives, and poetics, and names the representatives of the Gothic literary tradition in the English novel. The following chapter introduces the author David Mitchell and his work in the context of contemporary British literature in comparison with other authors of the Gothic tradition in contemporary literature (Neil Gaiman). The core of the work is a literary analysis of the novel Slade House, which focuses on the narrative technique of the novel (alternation of narrators), Gothic elements of horror atmosphere and suspense gradation, elements of fantastic literature (ghosts in the house) and the concept of a haunted house based on the studies of M. Aguirre (The Closed Space), etc. The thesis mentions Royle´s theoretical concept of The Uncanny and in the final section it attempts to capture the essence of the concept in Mitchell´s Slade House
0749: Nelson Slade Bond Collection, 1920-2006
No full textNelson Slade Bond had a varied writing career that spanned 70 years. Primarily known for science fiction short stories, Bond also wrote plays, radio and television scripts, newspaper and magazine articles, poetry, public relations material, and books. The collection reflects the author\u27s professional and personal lives consisting of writings, correspondence, business papers and financial records from 1925 to 2005. The collection was donated in four installments during and after Bond’s life from April 2006 to September 2007. The order in which the materials were received is maintained with only minor modifications. Input from Nelson Bond and his family members was considered and utilized in processing the collection.
The collection has approximately 370 magazines containing stories published by Nelson Bond. Although Bond wrote detective and sport stories, he is primarily known as a science fiction and fantasy author from the Golden Age of science fiction contemporary to authors such as Robert Bloch, A.E. Van Vogt, Isaac Asimov, and Ray Bradbury to name a few. Magazines from 1938 to 1999 such as Planet Stories, Fantastic Adventures, Weird Tales, and Amazing Stories are included in the first seven boxes. Also included are 200 short stories, 80 television and play scripts, 200 radio scripts, six books of short stories, three novel length stories, galley proofs and magazine and newspaper articles. Memorabilia from the collection is located in the Nelson Bond Room
Office Rent Determinants during Market Decline and Recovery
No full textThis article empirically examines office rent determinants in distinct periods of a market cycle. The study uses a dataset of office properties located in a large metropolitan area and spanning a six-year period. During this period, office rents experienced a significant decline and recovery. A time-varying parameter rent index identifies three distinct periods of the cycle: decline, trough and recovery. Tests of structural change conclude that market participants value the determinants of office rents differently during the periods. A microexamination of each rent determinant over the periods of the market cycle provides a greater understanding of how rents vary over time and the factors that influence them.
Silence at the end of the rainbow : an analysis of the effects of rainbowism on post-apartheid South African cinema
No full textIf one reads a broad sample of interviews that have been conducted with South African filmmakers or film writers, then one might start to see a pattern in the types of complaints that emerge. Among these common complaints, one finds a widespread belief that the state is generally unwilling to fund certain types of films, and that contemporary South African audiences will avoid certain types of films. This dissertation explored whether the concept of Rainbowism could be adapted to theorise some reasons as to why the South African film industry seems to privilege certain narratives, whilst silencing others. A situation that is troubling when one considers South Africa's recent history. To accomplish this task, the author did a vast amount of reading on the subject of Rainbowism in general and on post-apartheid South African cinema in particular. From these numerous sources a way forward was synthesised. Rainbowism was defined in terms of myth and counter myth and its role in the creation of a new post-apartheid South African identity was also explored. Following this, South African cinema was historically contextualised and the state film-funding environment was explored. This was done in order to see the engagement between Rainbowism and the various funding bodies. It was shown that the emphasis on adapting to the post-apartheid state's neo-liberal economic policies had resulted in a situation in which film financing bodies such as the National Film and Video Foundation did not allow for audiences to grow in response to films. Rather, films had to be tailored to suit the preferences of existing audiences. This had a negative effect on those filmmakers that sought to try new things for which there might not yet have been an audience. Furthermore, it was also shown that South Africa's relatively peaceful transition from apartheid to democracy has become a feature of international co-productions; the desire to sell the idea of the rainbow nation has effected the types of engagements with the past that are displayed in these films
Micro-algae cultivation for biofuels: Cost, energy balance, environmental impacts and future prospects
No full text02.09.13 KB. Ok to add the author version. Elsevier says ok while mandate not enforced
Testing Optimal Punishment Mechanisms under Price Regulation: the Case of the Retail Market for Gasoline
No full textWe analyse the effects of a price floor on price wars (or deep price cuts) in the retail market for gasoline. Bertrand supergame oligopoly models predict that price wars should last longer in the presence of price floors. In 1996, the introduction of a price floor in the Quebec retail market for gasoline serves as a natural experiment with which to test this prediction. We use a Markov Switching Model with two latent states to simultaneously identify the periods of price-collusion/price-war and estimate the parameters characterizing each state. Results support the prediction that price floors reduce the intensity of price wars but increase their expected duration.price regulation, oligopoly supergame, Markov switching model, gasoline
Saint Teresa of Avila
No full textWith few exceptions, representations of Renaissance women were created by men. The Spanish saint, Teresa of Avila (1515-1582), who chose to represent herself, was one of those exceptions. What prompted her to write Book of Her Life, Interior Castle , and other works? What does the self-portrait of this sixteenth-century nun, mystic, and founder of convents reveal about its author, the church, state, and role of women? St. Teresa of Avila , an innovative analysis of Teresa's autobiographical writings, explores these and many other questions. Bringing to bear a knowledge of Inquisition studies, theory of autobiography, scriptural hermeneutics, and hagiography, Carole Slade defines Teresa's writings as a project of self-interpretation undertaken mainly as the result of the perceived, later realized, threat of an accusation of heresy. Being female and of paternal Jewish ancestry, Teresa was vulnerable to such a charge.Teresa's writing project presented her with serious difficulties. Judicial confession, her prescribed genre, presumed the writer's guilt, while the subordinate female script precluded a defense against the suspicion that her mystical experiences came from the devil. Through careful textual analysis, Slade demonstrates that Teresa exploited the nuances of numerous genres - hagiography, New World chronicle, mystical theological treatise, and early novel - to create an innocent textual persona and depict herself in heroic terms.A signal contribution to our understanding of Teresa's rhetorical and literary talent and life circumstances, this book will engage readers across a broad range of disciplines
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