1,720,988 research outputs found

    First-Line Therapy for Vaginal Atresia. Conservative Treatment vs Surgical Techniques: Quandaries Looking at Numbers

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    Although it has been clearly stated that vaginal dilation must be considered the first-line treatment for clinical conditions characterized by an absent or hypoplastic vagina, mainly Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome, a great number of scientific papers on surgical vaginal reconstructions are reported every year. This wide variety of surgical techniques (more than 10) are recognized and performed worldwide, making it difficult to compare results and define an evidence-based approach. Standardized treatment should be considered even more important in the pediatric and adolescent population for the implications offered by the uterus transplantation scenario

    Business model configuration and dynamics for technology commercialization in mature markets.

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    Purpose The food industry is a well-established and complex industry. New entrants attempting to penetrate it via the commercialization of a new technological innovation could face high uncertainty and constraints. The capability to innovate through collaboration and to identify suitable strategies and innovative business models (BMs) can be particularly important for bringing a technological innovation to this market. However, although the potential for these capabilities has been advocated, we still lack a complete understanding of how new ventures could support the technology commercialization process via the development of BMs. The paper aims to discuss these issues. Design/methodology/approach To address this gap, this paper builds a conceptual framework that knits together the different bodies of extant literature (i.e. entrepreneurship, strategy and innovation) to analyze the BM innovation processes associated with the exploitation of emerging technologies; determines the suitability of the framework using data from the exploratory case study of IT IS 3D – a firm which has started to exploit 3D printing in the food industry; and improves the initial conceptual framework with the findings that emerged in the case study. Findings From this analysis it emerged that: companies could use more than one BM at a time; hence, BM innovation processes could co-exist and be run in parallel; the facing of high uncertainty might lead firms to choose a closed and/or a familiar BM, while explorative strategies could be pursued with open BMs; significant changes in strategies during the technology commercialization process are not necessarily reflected in a radical change in the BM; and firms could deliberately adopt interim strategies and BMs as means to identify the more suitable ones to reach the market. Originality/value This case study illustrates how firms could innovate the processes of their BM development to face the uncertainties linked with the entry into a mature and highly conservative industry (food)

    Motivations behind the EMAS stagnation and enabling measures to stimulate new registrations: characterization of Public Administrations and Private-owned organizations

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    The Eco-Management and Audit Scheme (EMAS) is a voluntary Regulation that defines a management instrument developed by the European Commission for companies and other organisations to evaluate, report, and improve their environmental performance.Today the EMAS is undergoing a revision process, in order to fit organizations’ and stakeholders’ requirements and increase its diffusion. Italy accounts for roughly 1,000 of the 4,000 certified European organizations, and, especially during the last five years, a growing number of organizations have not renewed the certification. This context determined a stagnation in the number of EMAS registered organizations. Thus, the aim of the survey is to investigate why a growing number of Italian organizations have dropped out of EMAS, and to identify which enabling measures would be more effective in order to encourage organizations to move back to the certification. The target of the questionnaire were the 339 Italian organizations that did not renew their EMAS registration between 2010 and 2015, there were 99 respondents. In this paper, certified Public Administrations and private-owned organizations are compared in order to delineate significant differences between the two groups. Concerning motivations for not renewing EMAS, implementation costs were the key reasons for both groups. Conversely, considering the possible enabling measures, while private-owned organizations demand long term tax benefits, Public Administrations prefer a greater consideration of EMAS in public funding. This paper systematically addresses the phenomenon for the first time, contributing to reducing the existing gap in literature, and providing an input to decision-makers who are overseeing the EMAS revision process

    Tourism management and industrial ecology: a theoretical review

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    Industrial Ecology (IE) is based on the relation between the natural ecosystem and economic ecosystem. The concept refers to the metaphorical relation between the natural and industrial ecosystems as a model for transforming unsustainable industrial systems. Several tools and strategies are particularly significant for the IE development. In other words, the primary purpose of industrial ecology is to assess and reduce the impact economic activities on the environment. Tourism, as an economic activity, resulting in a full range of environmental impacts, should be treated like any other industry. This paper propose uses a theoretical review focused on IE for to investigate what is the best way to implement industrial ecology in the tourism activities. It seemed interesting to search within the IE concept for a model for the tourism sector, one of the fields with the greatest environmental interaction and economic implications
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