75 research outputs found
CCDC 2127293: Experimental Crystal Structure Determination
No full textRelated Article: Thomas Freese, Bálint Fridrich, Stefano Crespi, Anouk S. Lubbe, Katalin Barta, Ben L. Feringa|2022|Green Chemistry|24|3689|doi:10.1039/D2GC00291
CCDC 2127292: Experimental Crystal Structure Determination
No full textRelated Article: Thomas Freese, Bálint Fridrich, Stefano Crespi, Anouk S. Lubbe, Katalin Barta, Ben L. Feringa|2022|Green Chemistry|24|3689|doi:10.1039/D2GC00291
The Total Cost of Living in Relation to Energy Efficiency Upgrades in the Dutch, Multi-Residential Building Stock
No full textDecarbonizing the housing stock is one of the largest challenges in the built environment today, and is getting attention not only from policymakers, but also from social housing corporations, financial and tenants’ organisations. In line with the international Paris-Climate-Change-Conference 2015, Dutch cities and housing associations have embraced this challenge with the ambitions to become carbon neutral in 2050. To reach such ambitious goals, both the rate and depth of renovation need to increase significantly. In the Netherlands, the Energy Agreement for Sustainable Growth, indicates that 300.000 dwellings have to be renovated annually, in accordance with the Energy Performance of Buildings Directive adopted by the European Union, to improve the Dutch building stock towards energy neutrality. Several technical solutions to eliminate the energy demand in dwelling have been developed and tested. Nevertheless, the intake rate of deep retrofitting is low. Currently, most improvements in residential buildings consist of basic maintenance and shallow renovation, but broader or deeper energy renovation measures are required. Despite more recent developments, there are still significant barriers related to financing, lack of information, and user acceptance. Complex technical characteristics are not always taken into account by tenants; the focus is usually on the ease of use, comfort and living expenses.To this end, the present study sets of to investigate the relationship between energy efficiency upgrade measures and cost of living. Focusing on the post-war, multi-family social housing in the Netherlands, a framework of refurbishment measures that affect the energy efficiency were identified, and their performance was simulated. The variations refer to the façade design, thermal envelope upgrade, winter-garden addition and reviewable energy. The energy efficiency indicator is the energy cost reduction, as well as the carbon footprint of the energy use. Furthermore, the rental price adjustment was estimated, taking into account the refurbishment investment and the operation cost of the renovated dwellings. All tested combination of variables resulted in significant energy savings, up to 70%, while energy generation was proven to be cost-effective, as it has a considerable positive effect on the energy use and the energy cost, without increasing the rental price.The results aim at supporting the decision-making discussion between the stakeholders, primarily housing associations and tenants. The relation between the energy consumption and rental price for the different options identifies the effect of design variation and demonstrated the attractive solutions that the tenants are more likely to accept, taking into account the overall cost of living and sustainability benefits.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Building Product InnovationHousing Institutions & GovernanceHousing ManagementDesign & Construction ManagementArchitectural Engineerin
Recent developments in reversible photoregulation of oligonucleotide structure and function
Get PDFThere is a growing interest in the photoregulation of biological functions, due to the high level of spatiotemporal precision achievable with light. Additionally, light is non-invasive and waste-free. In particular, the photoregulation of oligonucleotide structure and function is a rapidly developing study field with relevance to biological, physical and material sciences. Molecular photoswitches have been incorporated in oligonucleotides for 20 years, and the field has currently grown beyond fundamental studies on photochemistry of the switches and DNA duplex stability, and is moving towards applications in chemical biology, nanotechnology and material science. Moreover, the currently emerging field of photopharmacology indicates the relevance of photocontrol in future medicine. In recent years, a large number of publications has appeared on photoregulation of DNA and RNA structure and function. New strategies are evaluated and novel, exciting applications are shown. In this comprehensive review, the key strategies for photoswitch inclusion in oligonucleotides are presented and illustrated with recent examples. Additionally the applications that have emerged in recent years are discussed, including gene regulation, drug delivery and materials design. Finally, we identify the challenges that the field currently faces and look forward to future applications
Exploring molecular motors
Get PDFThe introduction of mechanical functions and controlled motion based on molecular motors and machines offers tremendous opportunities towards the design of dynamic molecular systems and responsive materials. In this brief perspective the focus is on the exploration of rotary molecular motors discussing basic principles and showing illustrative applications in functional materials. Furthermore, major challenges to bring dynamic properties to more complex molecular systems, ranging from transmission, amplification and synchronization to biocompatibility and autonomous behavior, are discussed. </p
Finding meaning in the profane: How libraries can evoke spiritual experiences
No full textReligion is in decline and spirituality starts to take on a more prominent role instead. Although there are abundant religious spaces, this shift did not cause a development in architecture yet. Libraries have similar qualities to religious spaces, like the sense of community and the feeling of retreat, so it is interesting to research how this typology can support spirituality. The Ets Haim library is the oldest Jewish library in the world and was founded to rediscover the Jewish identity of converted Jews who fled Spain and Portugal. This study aims to dissect the palimpsest of this library for a better understanding of the physical representation of spirituality by answering the question: How does Ets Haim Library support the notion of spirituality? There has been ample of research that addresses the impact of architecture on a transcending experience. Elements like urban context, light, geometry, materials and symbolism stand out as main influences, but it must be mentioned that spirituality is a subjective concept and it cannot be confined to a list of elements or a design manual. After a comprehensive analysis, it became clear that the Ets Haim supports spirituality by immaterial values like history, community and knowledge and material elements like geometry, light, colour and above that the book as a symbol.AR2A011Architectural History ThesisArchitecture, Urbanism and Building Science
Light‐driven Rotary Molecular Motors for Out‐of‐Equilibrium Systems
Get PDFThis chapter discusses whether rotary molecular motors are able to operate away from thermal equilibrium and whether this work on the molecular scale can be amplified across length scales and light-driven rotary motors. The chapter analyzes examples from literature demonstrating the ability of molecular motors to perform work, starting with examples in which a net output is generated by single molecules, followed by larger (supramolecular) systems. The molecular motors are overcrowded alkene switches, and the initial establishment of a photostationary state can be recognized as the photochemical equilibrium described for photoswitches. Surface immobilization is the possibilities to overcome Brownian motion and give opportunity to turn the relative rotation of one motor half with respect to the other into an absolute rotation of the motor with respect to the surface. Self-assembly opens up the possibility to work with very complex systems and enhance functions through cooperativity without the need of complicated synthesis of elaborate single molecules.</p
Designing dynamic functional molecular systems
Get PDFThe design and construction of dynamic functional molecular systems, which mimic some of the properties of living systems, pose a huge contemporary challenge. Recent developments in supramo-lecular self-assembly, molecular switches, motors and machines, and chemical reaction networks, offer an excellent basis for integrating dynamic properties in molecular systems. In this perspective, we discuss different approaches towards dynamic functional molecular systems covering areas such as translated motion, dissipative self-assembly, self-regulation and biohybrid systems. The selected examples illustrate the level of control and complexity that can be achieved at present in this rapidly growing and exciting field of research. (C) 2017 Published by Elsevier Ltd.</p
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