400 research outputs found
Summary of Advances in the Heat-Pulse Technique: Improvements in Measuring Soil Thermal Properties
No full textThis essay provides a summary of “Advances in the Heat-Pulse Technique: Improvements in Measuring Soil Thermal Properties” recently appearing in Methods of Soil Analysis. Series.This summary is published as Wen, Minmin, Gang Liu, Robert Horton, Yili Lu, and Tusheng Ren. "Summary of Advances in the Heat-Pulse Technique: Improvements in Measuring Soil Thermal Properties." Soil Science Society of America Journal (2018). doi: 10.2136/sssaj2018.02.0067.</p
sj-pdf-1-ppg-10.1177_03091333221087992 – Supplemental Material for Spatiotemporal variation in human settlements and their interaction with living environments in Neolithic and Bronze Age China
No full textSupplemental Material, sj-pdf-1-ppg-10.1177_03091333221087992 for Spatiotemporal variation in human settlements and their interaction with living environments in Neolithic and Bronze Age China by Guanghui Dong, Yongxiu Lu, Shanjia Zhang, Xiaozhong Huang and Minmin Ma in Progress in Physical Geography: Earth and Environment</p
sj-docx-1-tct-10.1177_15330338211045506 - Supplemental material for CTEN Inhibits Tumor Angiogenesis and Growth by Targeting VEGFA Through Down-Regulation of β-Catenin in Breast Cancer
No full textSupplemental material, sj-docx-1-tct-10.1177_15330338211045506 for CTEN Inhibits Tumor Angiogenesis and Growth by Targeting VEGFA Through Down-Regulation of β-Catenin in Breast Cancer by Xiangdong Lu, Bin Zhou, Minmin Cao, Qin Shao, Yukai Pan and Tao Zhao in Technology in Cancer Research & Treatment</p
sj-docx-2-tct-10.1177_15330338211045506 - Supplemental material for CTEN Inhibits Tumor Angiogenesis and Growth by Targeting VEGFA Through Down-Regulation of β-Catenin in Breast Cancer
No full textSupplemental material, sj-docx-2-tct-10.1177_15330338211045506 for CTEN Inhibits Tumor Angiogenesis and Growth by Targeting VEGFA Through Down-Regulation of β-Catenin in Breast Cancer by Xiangdong Lu, Bin Zhou, Minmin Cao, Qin Shao, Yukai Pan and Tao Zhao in Technology in Cancer Research & Treatment</p
sj-pdf-4-tct-10.1177_15330338211045506 - Supplemental material for CTEN Inhibits Tumor Angiogenesis and Growth by Targeting VEGFA Through Down-Regulation of β-Catenin in Breast Cancer
No full textSupplemental material, sj-pdf-4-tct-10.1177_15330338211045506 for CTEN Inhibits Tumor Angiogenesis and Growth by Targeting VEGFA Through Down-Regulation of β-Catenin in Breast Cancer by Xiangdong Lu, Bin Zhou, Minmin Cao, Qin Shao, Yukai Pan and Tao Zhao in Technology in Cancer Research & Treatment</p
sj-docx-3-tct-10.1177_15330338211045506 - Supplemental material for CTEN Inhibits Tumor Angiogenesis and Growth by Targeting VEGFA Through Down-Regulation of β-Catenin in Breast Cancer
No full textSupplemental material, sj-docx-3-tct-10.1177_15330338211045506 for CTEN Inhibits Tumor Angiogenesis and Growth by Targeting VEGFA Through Down-Regulation of β-Catenin in Breast Cancer by Xiangdong Lu, Bin Zhou, Minmin Cao, Qin Shao, Yukai Pan and Tao Zhao in Technology in Cancer Research & Treatment</p
Teaching Chinese language and culture to Australian students : Zhang Minmin's research story
No full textAs one of the supervisors of the second author, the first author of the paper reports Minmin's story of teaching Chinese language and culture to Australian students based on his interview with Minmin, and Minmin's Master of Education (Honours) thesis (Zhang, 2010). This paper is structured into three parts including the background of the story, experiencing difference in culture and education between China and Australia, and the summary of Minmin's research
sj-pdf-1-hol-10.1177_09596836221131698 – Supplemental material for Understanding the transport networks complex between South Asia, Southeast Asia and China during the late Neolithic and Bronze Age
No full textSupplemental material, sj-pdf-1-hol-10.1177_09596836221131698 for Understanding the transport networks complex between South Asia, Southeast Asia and China during the late Neolithic and Bronze Age by Minmin Ma, Yongxiu Lu, Guanghui Dong, Lele Ren, Rui Min, Lihong Kang, Zhonghua Zhu, Xiaorui Li, Bo Li, Zhijian Yang, Nongbu Cili, Ruiliang Liu, Yu Gao and Fahu Chen in The Holocene</p
Computed tomography angiography (CTA) of anomalous aortic origin of a coronary artery (AAOCA): Which measurements are accurate and reliable?
No full textBackground
The variation and accuracy of computed tomography angiography (CTA) features of anomalous aortic origin of a coronary artery (AAOCA) have not been completely characterized. We evaluated anomalous right (AAORCA) and left (AAOLCA) coronary arteries by CTA, with an emphasis on reproducibility, comparison with surgical measurements, and effect of nitroglycerin.
Methods
CTAs were interpreted for location of coronary origin & exit from the aorta, course, and dominance; minor & major diameters of the proximal & distal coronaries; shape of orifice; and intramural length. Relationships between vessel measurements, body surface area (BSA), and nitroglycerin use were evaluated. Comparisons between CTA and surgical measurements included intramural length, surgical probe size pre-intervention vs. CTA proximal AAOCA diameter, and surgical probe size post-intervention vs. CTA distal AAOCA diameter.
Results
Of 104 patients [81 (78%) AAORCA], all but 1 were intramural. Compared to AAOLCA, AAORCA patients were more likely to have a high origin (91% vs. 31%, p < 0.01), and slit-like orifice (58% vs. 26%, p < 0.01). When CTAs with nitroglycerin were compared to those without, no difference in proximal AAOCA dimensions was identified; however distal AAOCA and normal-origin coronary dimensions were larger in scans with nitroglycerin. Aside from slit-like orifice, reliability of coronary CTA measurements, including proximal AAOCA minor diameter and intramural length, was moderate to good between readers. In a subgroup of 54 patients, proximal AAOCA minor diameter and intramural length had good agreement and correlation with surgery.
Conclusion
Proximal AAOCA dimensions and intramural length are reproducible variables. The lack of difference in proximal AAOCA dimensions with nitroglycerin may reflect abnormal vessel mechanics. Multicenter studies are an important next step in understanding the generalizability of our findings
Mechanism through which retrocyclin targets flavivirus multiplication
No full textCurrently, there are no approved drugs for the treatment of flavivirus infection. Accordingly, we tested the inhibitory effects of the novel θ-defensin retrocyclin-101 (RC-101) against flavivirus infection, and investigated the mechanism underlying the potential inhibitory effects. First, RC-101 robustly inhibited both Japanese encephalitis virus (JEV) and Zika virus (ZIKV) infections. RC-101 exerted inhibitory effects on the entry and replication stages. Results also indicated that the non-structural protein NS2B-NS3 serine protease might serve as a potential viral target. Further, RC-101 inhibited protease activity at the micromolar level. We also demonstrated that with respect to the glycoprotein E protein of flavivirus, the DE loop of domain III, which is the receptor-binding domain of the E protein, might serve as another viral target of RC-101. Moreover, a JEV DE mutant exhibited resistance to RC-101, which was associated with deceased binding affinity of RC-101 to DIII. These findings provide a basis for the development of RC-101 as a potential candidate for the treatment of flavivirus infection.ImportanceRetrocyclin is an artificially humanized circular θ-defensin peptide, containing 18 residues previously reported to possess broad antimicrobial activity. In this study, we found that retrocyclin-101 inhibited flavivirus (ZIKV and JEV) infections. Retrocyclin-101 inhibited NS2B-NS3 serine protease activity, suggesting that the catalytic triad of the protease is the target. Moreover, retrocyclin-101 bound to the DE loop of the E protein of flavivirus, which prevented its entry
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