4,398 research outputs found
An asymptotic analysis of a tensile crack in creeping solids coupled with cumulative damage .1. Small damage region around the crack tip
In a material that undergoes creeping deformation coupled with damage, the stress field around the tip of a stationary Mode I crack is treated in two distinct limiting cases. In Part I of the context, a parameter perturbation method is used to study the tip stress field with small damage. Taking a dimensionless coefficient as a perturbation parameter, which characterizes the concerned damage scale, a series of asymptotic solutions can be obtained with the zeroth order approximation being the HRR type of solution. By the results derived one is able to arrive at the distribution of stress and strain, with the coupling effect of damage being taken into account. In this way one is expected to gain a detailed understanding to how the damage influences the HRR tip field. Discussion to another limiting case, which is concerned with the large damage zone very near the crack tip, will be carried out in Part II (Lu, hi., Lee, S. B., Kim, J. Y. and May, H. C. (1996). An asymptotic analysis of a tensile crack in creeping solids coupled with cumulative damage-part II. Large damage region very near the crack tip. Int. J. Solids Structures (accepted)). (C) 1997 Elsevier Science Ltd
An approximation lagrangian-based algorithm for the maximum clique problem via deterministic annealing neural network
The maximum clique problem is an NP hard combinatorial optimization problem, which is widely used in industrial and management processes. In order to approach the solution of the maximum clique problem, a deterministic annealing algorithm is proposed. When the barrier parameter is reduced from a large positive number to zero, the algorithm can track the minimum path of the obstacle problem to obtain a high-quality solution, which is a continuous method. The global convergence iteration of the Lagrange multiplier can be performed to obtain the minimum point of the obstacle problem in the feasible descent direction for any given positive value of the barrier parameter and has a desired property that it automatically satisfies the upper and lower bounds of variables if the steplength is a number that is between 0 and 1. Numerical results are provided to illustrate the efficiency of the proposed algorithm. (c) 2022 The Franklin Institute. Published by Elsevier Ltd. All rights reserved
Effects of air bubbles and tube transportation on blood oxygen tension in arterial blood gas analysis
Adiponectin SNP276 is associated with obesity, the metabolic syndrome, and diabetes in the elderly.
Synthesis of the possible metabolites of quinocetone in animals
The possible metabolites of quinocetone in animals had been prepared with different selective reagent by three synthetic routes. It was their principal reaction that Na2S2O4 reduced quinoxaline-1,4-dioxide derivatives to quinoxaline derivatives, H(2)O(2 s)oxidized 2-carboxyl-quinoxaline derivatives to 2-carboxyl-quinoxaline-1-oxide ones and P(OCH3)(3) reduced 2-carboxyl- quinoxaline-1,4-dioxide derivatives to 3-carboxyl-quinoxaline-1-oxide ones. The title compounds ware confirmed with NMR, UV, FAB-MS, et al
Additional role of nicotinic acid hydroxylase for the transformation of 3-succinoyl-pyridine by Pseudomonas sp. JY-Q
Applied Environmental Microbiology, 87, e02740-20Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.Nicotine and nicotinic acid (NA) are both considered to be representatives of N-heterocyclic aromatic compounds, and their degradation pathways have been revealed in Pseudomonas species. However, the cooccurrence of these two pathways has only been observed in Pseudomonas sp. strain JY-Q. The nicotine pyrrolidine catabolism pathway of strain JY-Q consists of the functional modules Nic1, Spm, and Nic2. The module enzyme, 3-succinoylpyridine monooxygenase (Spm), catalyzes transformation of 3-succinoyl-pyridine (SP) to 6-hydroxy-3-succinoyl-pyridine (HSP). There exist two homologous but not identical Spm enzymes (namely, Spm1 and Spm2) in JY-Q. However, when spm1 and spm2 were both in-frame deleted, the mutant still grew well in basic salt medium (BSM) supplemented with nicotine as the sole carbon/nitrogen nutrition, suggesting that there exists an alternative pathway responsible for SP catabolism in JY-Q. NicAB, an enzyme accounting for NA hydroxylation, contains reorganized domains similar to those of Spm. When the JY-Q_nicAB gene (nicAB in strain JY-Q) was introduced into another Pseudomonas strain, one that is unable to degrade NA, the resultant recombinant strain exhibited the ability to transform SP to HSP, but without the ability to metabolize NA. Here, we conclude that NicAB in strain JY-Q exhibits an additional role in SP transformation. The other genes in the NA cluster, NicXDFE (Nic2 homolog), then also exhibit a role in subsequent HSP metabolism for energy yield. This finding also suggests that the cooccurrence of nicotine and NA degradation genes in strain JY-Q represents an advantage for JY-Q, making it more effective and flexible for the degradation of nicotine.China Postdoctoral Science Foundationhttps://login.libproxy.rpi.edu/login?url=https://doi.org/10.1128/AEM.02740-2
Syntheses of novel fluoroquinolone compounds
A series of 1-substituted-6-fluoro-7-(1-(4-((Z)-2-(2-aminothiazol-4-yl)-2-methoxyi-m inoacetyl)piperazinyl))-1,4-dihydro-4-oxo-3-quinoline carboxylic acid has been prepared and evaluated for antibacterial activity. These compounds were prepared by the combination of 1-substituted- 6-fluoro-7- piperazinyl- 1,4-dihydro-4-oxo-3-quinolinecarboxylic acid and S-2-benzo- thiazoyl-(Z)-2-(2-aminothiazol-4-yl)-2-methoxyimino acetate(MAEM) under the condition of Schotten-Baumann. The title compounds are confirmed with NMR,UV, IR, FAB-MS, et al
CANONICAL ABERRATION THEORY FOR CALCULATING HIGHER-ORDER CHROMATIC ABERRATIONS
Canonical aberration theory has been developed in previous papers by the author. In the present study, the canonical aberration theory has been used to deal with first- and third-order chromatic aberrations (including position and momentum aberrations at an arbitrary observation plane) for rotationally symmetrical optical systems. All first- and third-order chromatic aberrations have been expressed in canonical matrix representations, which are general in nature and appropriate for computer calculations.Physics, AppliedSCI(E)3ARTICLE41962-19676
Selecive Catalytic Reduction of NOx in Lean Burn Engine Exhaust by Highly Active Pt Supported on V-impregnated MCM-41
On the Pt/V/MCM-41 catalyst with 1wt% Pt and 4wt% V, the maximum conversion of NO reduction into N2+N2O by C3H6 was about 73%, which was 10% higher than on 1wt% Pt/silica, and this maximum conversion was maintained over a temperature range of 70.DEG.C. between 270 and 340.DEG.C.. (author abst.
Successful pregnancy achieved by intracytoplasmic sperm injection using cryopreserved electroejaculate sperm for a couple both with spinal cord injury : a case report.
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