5,947 research outputs found
The role of Umkhonto we Sizwe (MK) in the national liberation struggle in South Africa with reference to the rural far northern Transvaal, 1976-1990
No full textIncludes bibliographical references (leaves 250-275)
The Short-term Effect of Acupuncture on Cortical Excitability in Patients with Parkinson’s Disease.
No full textExperiencing the armed struggle : the Soweto generation and after
No full textIncludes bibliographical references (p. 354-369).This study explores the experiences of the rank-and-file soldiers of Umkhonto we Sizwe and the Azanian People's Liberation Anny. Extensive interviews by the author and other researchers reveal the voices of the soldiers themselves. The African National Congress and Pan African Congress archives at the University of the Western Cape and the University of Fort Hare supplement and verify these oral testimonies, as do some published sources. Most previously published materials about the armed struggle against apartheid have already focused on diplomacy, strategy and tactics, operations, leadership, and human rights abuses to the neglect of the soldiers' actual experiences. This study complements these with significant new oral history materials from the Soweto generation of soldiers and their successors. When dealing with MK, many authors have documented issues of the camp structure in Angola, and operations inside South Africa, so much of this detail is only addressed briefly, leaving space to explore the soldiers' experiences. In the case of APLA, very little has been written on its history, and more detail is provided on these subjects. This study therefore deals with the soldiers' politicisation and motivation for joining the armed struggle, their experiences in leaving South Africa and training in exile, the crises in exile which limited their effectiveness for a time, their return to fight in South Africa, and their difficulties in the "new" South Africa. These materials reveal that vast problems remain facing these veterans of the struggle against apartheid, and that they have the potential, if properly supported and employed, to contribute substantially to the development of present day South Africa. Conversely, if their neglect continues, they also have the potential to bring vast harm to the country. Further use of the investigative tools of oral history, especially if extended to the former soldiers' vernacular languages, is necessary to augment the history of South Africa, and these soldiers' contributions
Two novel mutations of the glycine receptor gene and electrophysiological manifestation in a family with autosomal recessive hereditary hypereklpexia
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Dawn Aerospace Mk-III Spaceplane Aerothermodynamic Analysis
No full textDawn Aerospace is developing a horizontal take-off and landing two stage to orbit partially-reusable launcher concept. The re-usable first stage spaceplane operates on a return to launch site trajectory and integrates into the existing airspace, flying as an UAV. For any re-entry vehicle the design needs to account for aerothermodynamic behaviour around the vehicle, to ensure the structure can survive the re-entry temperatures. The unique mission of the Mk-III means the thermal design considerations are unique and provide a new engineering challenge and research topic. This thesis investigates the aerothermodynamic behaviour of the Mk-III flow and structure. A loosely coupled model was created for this purpose, which couples engineering methods to predict the aerothermodynamics and the thermal behaviour of the structure. The coupling is done by transferring the external skin temperature and convective heat flux between the two simulations. The primary research question for this thesis is “What thermal protection systems have potential to be implemented on the Dawn Aerospace Mk-III spaceplane for a range of different design trajectories.” Two thermal protection systems (TPS) and material choices have been identified as potential solutions. The first is a fully titanium structure, which can handle the temperature experienced by the Mk-III for all trajectories at every point along the vehicle. The second is a combined titanium and BMI CF structure with an insulation layer on the BMI CF. The titanium is required for the temperatures experienced on the vehicle’s leading edges, while the BMI CF has been identified as suitable in areas away from the leading edge if protected by an insulation TPS. A benefit this option produces is that the insulation layer can be changed in thickness to lighten the vehicle for lower design trajectories, therefore creating different vehicles for different trajectories. However, combining a metal with a composite could pose manufacturing issues such as cost for different manufacturing processes and joining problems. This thesis could not properly trade-off between these two options due to it being outside the scope of this thesis and due to limitations in detailed structural knowledge. These two material choices were chosen from four materials analysed in the thesis and four different TPS. Other TPS were not suitable at decreasing the structural temperature for the Mk-III mission or had an unjustifiable weight penalty. The other material choices would have been suitable in certain situations but were heavier than the current proposed options and might have required a TPS. This thesis provides valuable insight in what suitable material and TPS choices could be for the Mk-III mission. It also shows that for any future material and TPS choice to be made, a comprehensive structural analysis is required. Mass is a key trade-off parameter between the two proposed solutions and a better structural analysis is required for any further trade-off.Aerospace Engineerin
On the determinant of Up on Mk(p,χ)
No full textIn this work, for p a prime, we compute the absolute value of the determinant of the UpUp-operator on the vector space Mk(p,χ)Mk(p,χ) of holomorphic modular forms of weight k and level Γ0(p)Γ0(p) with character χχ. As an implication, we confirm a number of conjectures of the second author
Changing dogma regarding the conformation of electron transferring menaquinone (MK)
Full text link2017 Spring.Includes bibliographical references.Menaquinone-9 (MK-9) is the natural substrate containing a naphthoquinone and an isoprenyl side-chain with nine isoprene units that carry out the electron transfer for the Mycobacterium tuberculosis. We present studies aiming to understand the chemical and biochemical properties of hydrophobic MK molecules. Specifically, we are investigating the MK derivative with two isoprene units, MK-2, because it provides us with the base structure containing the naphthoquinone unit and the isoprene side-chain. Its synthesis is relatively simple because the precursors are commercially available, which allows for large scale preparation and detailed characterization of the molecular structure under different conditions. Using 1D and 2D 1H NMR studies we are establishing that MKs have different conformations depending on the specific environmental conditions. Similarly, we show using 1H-1H 2D NOESY NMR studies that the association of MK with the surfactant- water interface of reverse micelles, which is a model membrane system, modify the conformation of the menaquinone derivative. Finally, the redox potentials of MK-2 was measured in the three different solvents (DMSO, CH3CN and pyridine). We hypothesize that the redox potential is correlated to the conformational of the MK. We observed that the redox potentials varied with solvent. The observed folded structures of MK derivatives stand in contrast to the linear conformation shown in life science text books
Different manifestations of movement-related cortical potentials in patients with Parkinson’s disease with and without rest tremor.
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