109,732 research outputs found
Lowe, K W, SX6396
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/400172Surname: LOWE. Given Name(s) or Initials: K W. Military Service Number or Last Known Location: SX6396. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 34725.218443
Item: [2016.0049.32465] "Lowe, K W, SX6396
Lowe, W R K, TX8257
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/400175Surname: LOWE. Given Name(s) or Initials: W R K. Military Service Number or Last Known Location: TX8257. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 31335.218446
Item: [2016.0049.32468] "Lowe, W R K, TX8257
Joshua Davis: Author of Spare Parts
Get PDFCitation: K-State First (2016). Joshua Davis: Author of Spare Parts [Flier]. Manhattan, Kansas: K-State First.Flyer advertising Joshua Davis's author talk at Kansas State University
Steven Johnson Author Talk Poster
No full textK-State Book NetworkA poster advertising an author talk by Steven Johnson at Kansas State University on September 3, 2014. Steven Johnson's book "The Ghost Map" was the 2014-2015 common book
Study of the cell biological role of Lowe Syndrome protein OCRL1
No full textOculocerebrorenal syndrome of Lowe (OCRL) is caused by mutations in a
phosphatidylinositol 5-phosphatase, OCRL1, and is believed to lead to an
elevation of its preferred substrate, PI(4,5)P2. To date, much of the work on
OCRL1 has centred on its role at Golgi and endosomal membranes.
However, there is also evidence of plasma membrane activity for OCRL1,
where its PI(4,5)P2 substrate is known to be highly abundant. PI(4,5)P2
regulates a wide array of downstream cellular functions such as cytoskeletal
dynamics, membrane trafficking and signalling. The tight regulation of
PI(4,5)P2 levels and localisation, like other phosphoinositides, provides a
framework upon which many of these cellular processes work. In this thesis,
effects of OCRL1 loss have been tested through siRNA depletion of OCRL1,
focussing where possible on multiple PI(4,5)P2-dependent mechanisms, and
also focussing on cells forming polarised epithelia. Firstly, we have visualised
the localisation of PI(4,5)P2 in living HeLa cells lacking OCRL1 through
immunostaining for Annexin A2, which showed a marked translocation to the
plasma membrane. This change in distribution of Annexin A2 suggested that
OCRL1 depletion may have an effect on intracellular calcium dynamics as
well as PI(4,5)P2 localisation. We also used a GFP-chimera of the well
characterised PI(4,5)P2-binding pleckstrin homology domain of PLCδ1. This
showed no difference in localisation upon OCRL1 depletion. As OCRL1 is
highly enriched at the TGN, we fused the pleckstrin homology domain of
PLCδ1 to a mutated pleckstrin homology domain of OSBP known to bind ARF1 at the TGN, to act as a coincidence detector for PI(4,5)P2 at the TGN.
This construct also showed no reproducible effect of OCRL1 depletion.
Secondly we tested the effect of loss of OCRL1 on cytosolic calcium levels.
Using two phospholipase C (PLC) agonists, and a SERCA pump inhibitor, we
found no consistent differences in calcium handling upon depletion of OCRL1.
Thirdly, we have assessed the potential specialised role that OCRL1 has in
polarised epithelial cells, which might relate to the clinical picture in Lowe
Syndrome. We found that OCRL1 targets the tight junctions of immortalised
lines and primary cells. Through co-immunoprecipitation, we found OCRL1 in
complexes with the tight junction scaffold protein ZO-1. Most significantly, we
found that depletion of OCRL1 in human polarised epithelial cell lines
interfered with epithelial differentiation, reducing cell number and altering
morphology, to produce large flat cells. We attribute this phenotype, stronger
than any other so far described experimentally, to a defect in tight junction
maturation
Gint Kovarik, Lowe, Pliskova et Stahlavsky 2013
No full text<i>Gint</i> Kovařík, Lowe, Plíšková et Šťáhlavský, 2013 <p>(Figs. 1–62, Table 1)</p> <p> <i>Buthus</i> (<i>Buthacus</i>) (in part): Birula, 1917: 21.</p> <p> <i>Buthacus</i> (in part): Levy, Amitai & Shulov, 1973: 125; Fet & Lowe, 2000: 81; Kovařík, 2005: 1.</p> <p> <i>Gint</i> Kovařík et al., 2013: 1–18, figs. 1–4, 6–71; Kovařík & Mazuch, 2015: 1–23, figs. 1–89;? Rossi, 2015: 53–63, figs. 1–10; Kovařík et al., 2018: 1–41, figs. 1–202, tables 1–3; Kovařík, 2018: 1–9, figs. 1–42, table 1.</p> <p> TYPE SPECIES. <i>Gint gaitako</i> Kovařík et al., 2013.</p> <p> ETYMOLOGY. <i>Gint</i> (masculine) means scorpion in Amharian, the official language of Ethiopia.</p> <p>DISTRIBUTION (Fig. 62). Ethiopia, Kenya, Somalia, Somaliland.</p> <p> DIAGNOSIS. Total length up to 25 mm (male) or 50 mm (female); carapace trapezoidal, in lateral view preocular area not distinctly inclined towards anterior margin, level with or higher than postocular area; surface of carapace densely granular, with only anterior median carinae developed; ventral aspect of cheliceral fixed finger with two denticles (Fig. 51); tergites densely granular, with three carinae of which lateral pair on I and II are inconspicuous; sternites III–VI with finely micro-denticulate posterior margins, lacking larger noncontiguous denticles; pectinal tooth number 19–31; pectines with fulcra, hirsute; hemispermatophore with flagellum separated from a 3-lobed sperm hemiduct, and with a projecting, scoop- or hook-like basal lobe; metasomal segments I–III with 8–10 carinae; metasoma I ventrally smooth, lacking ventromedial carinae; metasoma V with enlarged ‘lobate’ dentition on ventrolateral carinae which may be reduced; telson rather elongate (except for <i>G. maidensis</i>), vesicle with moderate posterior slope, not sharply inclined or truncated, lacking subaculear tubercle, aculeus shorter than vesicle; all segments of metasoma and pedipalps sparsely hirsute, with long setae in both sexes, dentate margin of movable finger of pedipalp with 8–10 rows of granules, each with one external and one internal accessory granule, 5–6 terminal granules (4–5 subterminal and one distal terminal); trichobothrial pattern orthobothriotaxic type A; dorsal trichobothria of femur arranged in β- configuration; pedipalp patella with 7 external trichobothria; patella trichobothrium <i>d</i> 3 internal to dorsomedian carina; tibial spurs present on legs III–IV.</p> <p> SUBORDINATE TAXA. <i>Gint amoudensis</i> Kovařík et al., 2018; <i>Gint banfasae</i> <b>sp</b>. <b>n</b>.; <i>Gint calviceps</i> (Pocock, 1900); <i>Gint childsi</i> Kovařík, 2018; <i>Gint dabakalo</i> Kovařík et Mazuch, 2015; <i>Gint gaitako</i> Kovařík et al., 2013; <i>Gint gubanensis</i> Kovařík et al., 2018; <i>Gint maidensis</i> Kovařík et al., 2018; <i>Gint puntlandus</i> Kovařík et Mazuch, 2015. For species described by Rossi (2015) see Kovařík et al. (2018: 12).</p>Published as part of <i>Kovařík, František & Lowe, Graeme, 2019, Scorpions of the Horn of Africa (Arachnida Scorpiones) Part XVIII Gint banfasae sp n from Somaliland (Buthidae), pp. 1-14 in Euscorpius 272</i> on pages 1-5, DOI: 10.18590/euscorpius.2019.vol2019.iss272.1, <a href="http://zenodo.org/record/5510156">http://zenodo.org/record/5510156</a>
Defining absolute environmental limits for the built environment
No full textThe question addressed is whether it is possible to define working limits on environmental impacts from the built environment in terms of global carrying capacity. The main focus is on energy-related impacts, since these are global and relatively well-understood. Four possible approaches to defining limits are explored: static equilibrium, asymptotic, integral of excess and planned future. The conclusions that emerge from this exploration are that global environmental constraints are very tight, but also that they are dynamically and strongly influenced by the trajectory of social and technological development over the coming century. Their use as the basis for practical, quantitative metrics of sustainability, therefore, involves a large measure of subjectivity. A fifth approach - the developmental approach - is identified, which instead of focusing on long-term external constraints to human activity, focuses instead on the internal, short- to medium-term dynamics of the built environment itself. It appears likely that the developmental approach, guided by qualitative conclusions from the analysis of global carrying capacity, is likely to be most fruitful
History of Edward Kingsford
No full textTypescript (13 pages) with biographical notes by Edward Kingsford, including early life to his conversion to LDS Church in 1849 and immigration to America in 1853, followed by entries for each year to 1883 (perhaps from a journal), and testimonies from 1894, 1895, 1896 by people who experienced healing by Kingsford\u27s administrations. Original donated by Mrs. Syrena K. Lowe of Franklin, Idaho, May 18, 1946, probably typed by her for that purpose, transcribing original source
Barbaracurus exquisitus Kovařík & Lowe & Šťáhlavský 2018, comb. n.
No full text<i>Barbaracurus exquisitus</i> (Lowe, 2000) comb. n. <p>(Figures 5, 25, 33, 62–65, 70–71, 81–82, 90–100, 107– 112, 194–205, 252–254, 265)</p> <p> <i>Babycurus exquisitus</i> Lowe, 2000: 185–191, figs. 1–9; Kovařík, 2000: 244, fig. 38, tables 1–3; Soleglad & Fet, 2003a: 5; Soleglad & Fet, 2003b: 7; Fet et al., 2005: 14; Lowe, 2010: 17; Hendrixson, 2006: 109; Kovařík et al., 2015: 23.</p> <p>TYPE LOCALITY AND HOLOTYPE DEPOSITORY. Oman, Jabal Shams, Jabal Akhdar, Al Hajar Al Gharbi, 23º14. 29'N 57º11.62'E, 1855 m a.s.l., NHMB.</p> <p> MATERIAL EXAMINED. <b>Oman</b>, Jabal Shams, Jabal Akhdar, Al Hajar Al Gharbi (Fig. 112), 23º14.29'N 57º11.62'E, 1855 m a.s.l., 2.X.1994, leg. G. Lowe & M. D. Gallagher, 1♂ (holotype) 1♀ 1juv. (paratypes), NHMB; Jabal Shams, Jabal Akhdar, 23º14.31'N 57º11. 64'E, 1900 m a.s.l., 14.X.1993, leg. G. Lowe & M. D. Gallagher, 1♂ (paratype), NHMB; Jabal Akhdar hotel, Sayq plateau, 23º04'N 57º38'E, 1850 m a.s.l., 21. VI.2002, 1♂, leg. G. R. Feulner, GLPC.</p> <p>DIAGNOSIS. Total length of adult males 33–34 mm, adult female 39 mm. Coloration pale yellow, chela fingers, metasoma V and telson light orange, chelicerae yellow without reticulation (Figs. 252–253). Pedipalp chela manus much wider in male than female, chela length/width ratio 4.2–4.7 in males and 6.12 in female; proximal margins of pedipalp fingers of female straight (Figs. 65, 204), of male undulate so as to leave a gap with fingers closed (Figs. 63, 201); dentate margin of movable finger armed with 7 rows of granules, and a short apical row of 5 denticles (Fig. 6); most proximal granule row with one external accessory granule. Pectines with 21–22 teeth in both sexes. Hemispermatophore basal lobe a strongly raised carina (Figs. 25, 33). No sexual dimorphism in length and width of metasomal segments (Figs. 70–71); metasoma I with 10 carinae, II–IV with 8 carinae. Telson setose, bearing numerous long macrosetae and short, pointed subaculear tubercle (Figs. 80–82, 107–109); vesicle smooth, elongate, pyriform, telson length/depth ratio 2.70 in male, 2.89 in female; aculeus slender, curved, shorter than vesicle.</p>Published as part of <i>Kovařík, František, Lowe, Graeme & Šťáhlavský, František, 2018, Review of the genus Babycurus Karsch, 1886 (Arachnida, Scorpiones, Buthidae), with descriptions of Barbaracurus gen. n. and two new species from Oman and Yemen, pp. 1-41 in Euscorpius 267</i> on page 11, DOI: <a href="http://zenodo.org/record/6544157">10.5281/zenodo.6544157</a>
Correction to: The possibilities and practicalities of professional learning in support of Indigenous student experiences in schooling: A systematic review
No full textCorrection to: The Australian Educational Researcher https://doi.org/10.1007/s13384-019-00313-7
In the original publication of the article, the author group was incorrectly published without the co-authors. The correct author group is “Greg Vass, Kevin Lowe, Cathie Burgess, Neil Harrison, Nikki Moodie”.No Full Tex
- …
