2,189 research outputs found

    Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (Nature Communications, (2020), 11, 1, (4748), 10.1038/s41467-020-18151-y)

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    The original version of this Article omitted from the author list the 9th author Yize Li, who is from the ‘The McDonnell Genome Institute at Washington University, St. Louis, MO 63108, USA and Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, MO 63108, USA’. This has been corrected in both the PDF and HTML versions of the Article

    Determination of normal joint spacing from apparent joint spacing measurements

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    Normal joint spacing is either measured directly from parallel joint members of the same set or indirectly obtained from the apparent joint spacing measurements. The latter is achieved by considering the geometrical relationship between the joint orientation and the scanline/rock core orientation. In common practice, one can compute either an individual weighting factor for each member in the joint set, or only one weighting factor for the entire joint set based on the mean joint set orientation. These methods yield the same normal joint spacing values if the joint members are perfectly parallel. However, natural joints are rarely perfectly parallel, resulting in the discrepancy (error) of normal joint spacing. In this paper, another means for determining the normal joint spacing from apparent joint spacing based on the geometrical relationship between the scanline orientation and the averaged orientation of two adjacent joint members of the same set is examined. A detailed analysis is conducted on different sizes of randomly-generated joint set data with respect to differently oriented scanlines. The absolute error of the normal joint spacing calculations obtained by proposed method, which is found to be always smaller than that by the conventional practice, is thus recommended. © 2013 Taylor & Francis Group, London.link_to_subscribed_fulltex

    Arylchlorocarbenes in the synthesis of heterocycles containing two nitrogen atoms

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    Substituted pyrazoles and pyrrolo[1,2-c]pyrimidines were prepared from the reaction of arylchlorocarbenes with 1,2-diazabuta-1,3-dienes and 4-vinylpyrimidines, respectively.PT: J; CR: ATTANASI A, 1998, J ORG CHEM, V63, P9880 ATTANASI OA, 1977, SYNLETT, P1128 ATTANASI OA, 1999, TETRAHEDRON LETT, V40, P3891 BONINI BF, 1981, J CHEM SOC P1, P2322 BONNEAU R, 1999, J PHOTOCH PHOTOBIO A, V126, P31 GRAHAM WH, 1965, J AM CHEM SOC, V87, P4396 KUEHNE ME, 1964, J ORG CHEM, V29, P1582 LIU MTH, 1994, INT J CHEM KINET, V26, P1179 MAIBORODA DA, 1997, J ORG CHEM, V62, P7100 MINGUEZ JM, 1996, J ORG CHEM, V61, P4655 MOYANO EL, 1998, J ORG CHEM, V63, P8188 OVERBERGER CG, 1954, J AM CHEM SOC, V76, P1879 PERKAMPUS HH, 1972, TETRAHEDRON, V28, P2099 ROMASHIN YN, 1999, CHEM COMMUN 0307, P447 ROMASHIN YN, 1999, TETRAHEDRON LETT, V40, P7163 WONG JL, 1965, J ORG CHEM, V30, P2398; NR: 16; TC: 6; J9: CHEM COMMUN; PG: 2; GA: 324XFSource type: Electronic(1

    Interethnic differences in the accuracy of anthropometric indicators of obesity in screening for high risk of coronary heart disease.

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    BACKGROUND: Cut points for defining obesity have been derived from mortality data among Whites from Europe and the United States and their accuracy to screen for high risk of coronary heart disease (CHD) in other ethnic groups has been questioned. OBJECTIVE: To compare the accuracy and to define ethnic and gender-specific optimal cut points for body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) when they are used in screening for high risk of CHD in the Latin-American and the US populations. METHODS: We estimated the accuracy and optimal cut points for BMI, WC and WHR to screen for CHD risk in Latin Americans (n=18 976), non-Hispanic Whites (Whites; n=8956), non-Hispanic Blacks (Blacks; n=5205) and Hispanics (n=5803). High risk of CHD was defined as a 10-year risk > or =20% (Framingham equation). The area under the receiver operator characteristic curve (AUC) and the misclassification-cost term were used to assess accuracy and to identify optimal cut points. RESULTS: WHR had the highest AUC in all ethnic groups (from 0.75 to 0.82) and BMI had the lowest (from 0.50 to 0.59). Optimal cut point for BMI was similar across ethnic/gender groups (27 kg/m(2)). In women, cut points for WC (94 cm) and WHR (0.91) were consistent by ethnicity. In men, cut points for WC and WHR varied significantly with ethnicity: from 91 cm in Latin Americans to 102 cm in Whites, and from 0.94 in Latin Americans to 0.99 in Hispanics, respectively. CONCLUSION: WHR is the most accurate anthropometric indicator to screen for high risk of CHD, whereas BMI is almost uninformative. The same BMI cut point should be used in all men and women. Unique cut points for WC and WHR should be used in all women, but ethnic-specific cut points seem warranted among men

    © Hindawi Publishing Corp. ON THE L2w-BOUNDEDNESS OF SOLUTIONS FOR PRODUCTS OF QUASI-INTEGRO DIFFERENTIAL EQUATIONS

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    Given a general quasidifferential expressions τ1,τ2,...,τn each of order n with complex coefficients and their formal adjoints are τ+1,τ 2,...,τ n on [0,b), respec-tively, we show under suitable conditions on the function F that all solutions of the product of the quasi-integrodifferential equation [ ∏n j=1τj]y =wF(t,y, ∫ t 0 g(t,s, y,y′,...,y(n2−1)(s))ds) on [0,b), 0<b ≤∞; t,s≥0, are bounded and L2w-bounded on [0,b). These results are extensions of those by the author (1994), Wong (1975)

    Rock ’n’ roll, nueva ola y rock de garaje: una explicación estética del surgimiento de la música rock en el Perú

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    In their most widespread texts, peruvian rock historians promote semantic ambiguities around terms as rock ’n’ roll , «nueva ola» and rock music, and leave an explanatory gap in relation to the rise of rock music in Peru. This article clarifies these ambiguities and offers an explanation to the rise of rock music in Peru. The author proposes an aestheric approach based on social functions that musicians and listeners assign to a set of musical parameters in a certain historical context. In the end, the article clarifies the meaning of the terms that designate these music genres, and shows that the rise of rock music in Peru involved the continuity of some features of the genres that preceded it, and the appearance of innovations sufficiently important as to define the birth of a new musical genre in this country. En sus textos más difundidos, los historiadores del rock peruano promueven ambigüedades semánticas en torno a los términos rock, nueva ola y rock ’n’ roll, y dejan abierto un vacío explicativo en relación con la aparición de la música rock en el Perú. Este artículo busca aclarar estas ambigüedades y ofrecer una explicación al surgimiento del rock en el Perú. Para ello, el autor propone una aproximación estética basada en las funciones sociales que músicos y oyentes le asignan a un conjunto de parámetros musicales en un determinado contexto histórico. Por último, el artículo aclara el significado de los términos que designan a los géneros musicales ya mencionados y demuestra que el surgimiento del rock en el Perú involucró la continuidad de algunas características de los géneros que lo precedieron, así como innovaciones lo suficientemente importantes como para designar la aparición de un nuevo género musical en este país

    Singaporean mothers' perception of their three-year-old child's weight status: A cross-sectional study

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    Singapore National Research Foundation; National Medical Research Council (NMRC), SingaporeFull Author List: Cheng T.S.; Cheng T.; Loy S.; Cheung Y.; Chan J.; Tint M.; Godfrey K.; Gluckman P.; Kwek K.; Saw S.; Chong Y.; Lee Y.; Yap F.; Lek N.; Sheppard A.; Chinnadurai A.; Goh A.; Rifkin-Graboi A.; Qiu A.; Biswas A.; Lee B.; Broekman B.; Quah B.; Shuter B.; Chng C.; Ngo C.; Hsu S.; Bong C.; Henry C.; Chee C.; Fok D.; Yeo G.; Inskip H.; Chen H.; Van Bever H.; Magiati I.; Wong I.; Lau I.; Kapur J.; Richmond J.; Holbrook J.; Gooley J.; Tan K.; Niduvaje K.; Singh L.; Su L.; Daniel L.; Shek L.; Fortier M.; Hanson M.; Chong M.; Rauff M.; Chua M.; Meaney M.; Teoh O.; Wong P.; Agarwal P.; Van Dam R.; Rebello S.; Chong S.; Cai S.; Soh S.; Lim S.; Rajadurai V.; Stunkel W.; Han W.; Pang W.; Goh Y.; Chan Y.</p
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