69 research outputs found
Biomechanical characterization of human superficial fascia: thoracic vs abdominal district
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Artificial Intelligence Approaches for Low Back Pain: towards new frontiers of rehabilitation
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Urinary Incontinence and Other Pelvic Floor Dysfunctions as Underestimated Problems in People under Forty Years: What Is Their Relationship with Sport?
No full textFEM characterization and multi-object optimization of a compliant mechanism amplifier for massive gravitational antenna
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Design, implementation and effectiveness of human fascia lata biomechanics for tissue engineering
Get PDFThe fascia lata (FL) is a multi-layered connective tissue with anisotropic mechanical behavior due to its fiber organization. It plays a key role in musculoskeletal functionality, making it important in tissue engineering. Understanding its mechanical response to stimuli like movement or applied pressure is crucial, as the elastic and viscoelastic behavior can vary significantly based on morphological characteristics, harvesting site, and load direction. Thus, the aim of this review is to summarise through a gap analysis the scientific literature on the biomechanical properties of the human FL, identifying all those features (from the experimental set up to its inherent structural variability) that could affect its biomechanical behaviour, and thus unveiling these emerging correlations. Our research reported key mechanical properties of the FL, such as Young's modulus, Ultimate Tensile Strength, failure strain, and anisotropic response, which are crucial for designing and applying obtained allografts and autografts in soft tissue repair. These insights can help surgeons optimize graft applications-selecting the proper harvesting location, technique, graft type, and suture size-and guide clinicians in rehabilitation for personalized medicine
Biomechanical properties of the human superficial fascia: Site-specific variability and anisotropy of abdominal and thoracic regions
Get PDFSuperficial fascia is a fibrofatty tissue found throughout the body. Initially described in relation to hernias, it has only recently received attention from the scientific community due to new evidence on its role in force transmission and structural integrity of the body. Considering initial difficulties in its anatomical identification, to date, a characterization of the superficial fascia through mechanical tests is still lacking. The mechanical properties of human superficial fasciae of abdominal and thoracic districts (back) of different subjects (n = 4) were then investigated, focusing on anisotropy and viscoelasticity. Experimental tests were performed on samples taken in two perpendicular directions according to body planes (cranio-caudal and latero-medial axes). Data collected from two different uniaxial tensile protocols, failure (i.e., ultimate tensile strength and strain at break, Young's modulus and toughness) and stress-relaxation (i.e., residual stress), were processed and then grouped for statistical analysis. Failure tests confirmed tissue anisotropy, revealing the stiffer nature of the latero-medial direction compared to the cranio-caudal one, for both the districts (with a ratio of the respective Young's moduli close to 2). Furthermore, the thoracic region exhibited significantly greater strength and resultant Young's modulus compared to the abdomen (with greater results along the latero-medial direction, such as 6.13 ± 3.11 MPa versus 0.85 ± 0.39 MPa and 24.87 ± 15.23 MPa versus 3.19 ± 1.62 MPa, respectively). On the contrary, both regions displayed similar strain at break (varying between 38 and 47%), with no clear dependence from the loading directions. Stress-relaxation tests highlighted the viscous behavior of the superficial fascia, with no significant differences in the stress decay between directions and districts (35–38% of residual stress after 300 s). All these collected results represent the starting point for a more in-depth knowledge of the mechanical characterization of the superficial fascia, which can have direct implications in the design, implementation, and effectiveness of site-specific treatments
Mechanical Characterization of Human Fascia Lata: Uniaxial Tensile Tests from Fresh-Frozen Cadaver Samples and Constitutive Modelling
Get PDFHuman Fascia Lata (FL) is a connective tissue with a multilayered organization also known as aponeurotic fascia. FL biomechanics is influenced by its composite structure formed by fibrous layers (usually two) separated by loose connective tissue. In each layer, most of the collagen fibers run parallel in a distinct direction (with an interlayer angle that usually ranges from 75–80°), mirroring the fascia’s ability to adapt and withstand specific tensile loads. Although FL is a key structure in several musculoskeletal dysfunctions and in tissue engineering, literature still lacks the evidence that proves tissue anisotropy according to predominant collagen fiber directions. For this purpose, this work aims to analyze the biomechanical properties of ex-vivo FL (collected from fresh-frozen human donors) by performing uniaxial tensile tests in order to highlight any differences with respect to loading directions. The experimental outcomes showed a strong anisotropic behavior in accordance with principal collagen fibers directions, which characterize the composite structure. These findings have been implemented to propose a first constitutive model able to mimic the intra- and interlayer interactions. Both approaches could potentially support surgeons in daily practices (such as graft preparation and placement), engineers during in silico simulation, and physiotherapists during musculoskeletal rehabilitation, to customize a medical intervention based on each specific patient and clinical condition
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