10,001 research outputs found
Development of spectroscopic smartphone biosensors for point-of-care applications
No full textThis dissertation explores the combination of two emergent areas within contemporary biosensing, smartphone based spectroscopy and photonic crystal enhanced microscopy, and how these technologies can be combined to produce a fundamentally novel point-of-care testing paradigm: a portable device platform capable of non-amplifying, digital-detection for high-sensitivity diagnostics. In this work, I describe the development of this system, moving from usage-specific benchtop and smartphone based devices demonstrating proof-of-concept capabilities, to a multimodal smartphone platform compatible with thousands of existing spectroscopic assays. The resulting smartphone biosensor can perform various clinically-relevant tests with physiologically-relevant sensitivities. Next, photonic crystal enhanced microscopy is described for uses in the micrometer and nanometer scales for use both to study cellular and subcellular behavior and also to perform single-particle attachment quantification. Finally, this work explores how the single-particle attachment quantification capability can be leveraged to measure HIV viral load using a novel biosensor, designed specifically developed for a smartphone based platform for point of care applications.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2020-05-01The student, Kenneth Long, accepted the attached license on 2018-01-30 at 10:57.The student, Kenneth Long, submitted this Dissertation for approval on 2018-01-30 at 11:26.This Dissertation was approved for publication on 2018-01-31 at 13:32.DSpace SAF Submission Ingestion Package generated from Vireo submission #12025 on 2018-08-31 at 17:24:51Made available in DSpace on 2018-09-04T20:46:46Z (GMT). No. of bitstreams: 4
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Sermon "A Long Shot, But Worth It" Rosh HaShanah 1982
No full textThis sermon was delivered while Rabbi Roseman served as rabbi at Temple Beth El in Madison, Wisconsin
Political autobiography, nationalist history and national heritage: the case of Kenneth Kaunda and Zambia
No full textMagister Artium - MAThe research for this thesis started off as a long academic essay that sought to review a 1970s biography of Kenneth Kaunda.1 In its original focus, the study aimed at evaluating the work on the narrations of Kenneth Kaunda�s life from a theoretical and critical perspective. Specifically it sought to evaluate the biography for its theoretical and methodological approaches, its attention to issues of sources, archives, narrative and history. In addition, it aimed at locating the biography in relation to debates over biography and history in South Africa. As I began my research for the long essay, it soon became apparent that the biography of Kenneth Kaunda ended its narration in 1964 and yet it was published ten years later in 1974. By ending its �coverage� of the narrations of Kenneth Kaunda�s life in 1964, it seemed obvious that its coverage was in many ways similar to his autobiography that was published in 1962.2 The ending of the biography�s coverage in 1964 thus seemed rather abrupt as it precluded any representations of the subject in the post 1964 period in which he had become President of Zambia. Kenneth Kaunda was resident of Zambia for nearly three decades (1964-1991) having led the �final� phase of the nationalist struggle for Independence through the United National Independence Party (UNIP). Surely, I surmised, the meanings of Kenneth Kaunda�s life as nationalist leader, as presented in most of his biography, would differ from those of him as President? Upon evaluating the biography, it seemed to be a largely chronological and descriptive rather analytical account of the subject�s life. However, what made it profound to me was the ways in which it entwined the narratives of Kenneth Kaunda�s life with the events, dates 1 The biography of Kenneth Kaunda by Fergus Macpherson was the subject of the long essay. See Fergus Macpherson, Kenneth Kaunda of Zambia: The Times and the Man (Lusaka: Oxford University Press, 1974). 2 Kenneth D. Kaunda, Zambia Shall Be Free: An Autobiography (London: Heinemann Educational Books td, 1962). and activities of the history of the Zambian nation. Some accounts inadvertently referred to this interconnection by referring to Kenneth Kaunda as the �founder of Zambia�. My exposure to various other debates around the production of history in the public domain such as through museums and national heritage sites or monuments prompted me to consider undertaking a study of the post-1964 historiography of Kenneth Kaunda. Rather than attempting to fill Kenneth Kaunda�s post-1964 historiographical gap with a chronological account of his political life, I wanted to trace the narratives of Kenneth Kaunda�s life in connection with the production of history in different domains in Zambia. This thesis thus aims at examining the political auto/biographical narrations of Kenneth Kaunda in relation to the production of nationalist history and national heritage in Zambia in the years following the country�s Independence in 1964.4 One of the key questions that this study sought to engage with was: how did the �representations� of Kenneth Kaunda influence the ways in which Zambia�s post-independence nationalist history and national heritage were produced? In seeking to provide an answer to the question, the study evaluated the auto/biography of Kenneth Kaunda itself, as well as how it reflects in the history texts utilised in Zambian schools and in history in the public domain through national heritage sites or monuments and museum exhibitions. The thesis will show that in Zambia, the auto/biography of Kenneth Kaunda has acquired significance through history as school lesson and as history in the public domain, through the production of national heritage sites and museum exhibitions
Political autobiography, nationalist history and national heritage: the case of Kenneth Kaunda and Zambia
No full textMagister Artium - MAThe research for this thesis started off as a long academic essay that sought to review a 1970s biography of Kenneth Kaunda.1 In its original focus, the study aimed at evaluating the work on the narrations of Kenneth Kaunda’s life from a theoretical and critical perspective. Specifically it sought to evaluate the biography for its theoretical and methodological approaches, its attention to issues of sources, archives, narrative and history. In addition, it aimed at locating the biography in relation to debates over biography and history in South Africa. As I began my research for the long essay, it soon became apparent that the biography of Kenneth Kaunda ended its narration in 1964 and yet it was published ten years later in 1974. By ending its ‘coverage’ of the narrations of Kenneth Kaunda’s life in 1964, it seemed obvious that its coverage was in many ways similar to his autobiography that was published in 1962.2 The ending of the biography’s coverage in 1964 thus seemed rather abrupt as it precluded any representations of the subject in the post 1964 period in which he had become President of Zambia. Kenneth Kaunda was resident of Zambia for nearly three decades (1964-1991) having led the ‘final’ phase of the nationalist struggle for Independence through the United National Independence Party (UNIP). Surely, I surmised, the meanings of Kenneth Kaunda’s life as nationalist leader, as presented in most of his biography, would differ from those of him as President? Upon evaluating the biography, it seemed to be a largely chronological and descriptive rather analytical account of the subject’s life. However, what made it profound to me was the ways in which it entwined the narratives of Kenneth Kaunda’s life with the events, dates 1 The biography of Kenneth Kaunda by Fergus Macpherson was the subject of the long essay. See Fergus Macpherson, Kenneth Kaunda of Zambia: The Times and the Man (Lusaka: Oxford University Press, 1974). 2 Kenneth D. Kaunda, Zambia Shall Be Free: An Autobiography (London: Heinemann Educational Books td, 1962). and activities of the history of the Zambian nation. Some accounts inadvertently referred to this interconnection by referring to Kenneth Kaunda as the ‘founder of Zambia’. My exposure to various other debates around the production of history in the public domain such as through museums and national heritage sites or monuments prompted me to consider undertaking a study of the post-1964 historiography of Kenneth Kaunda. Rather than attempting to fill Kenneth Kaunda’s post-1964 historiographical gap with a chronological account of his political life, I wanted to trace the narratives of Kenneth Kaunda’s life in connection with the production of history in different domains in Zambia. This thesis thus aims at examining the political auto/biographical narrations of Kenneth Kaunda in relation to the production of nationalist history and national heritage in Zambia in the years following the country’s Independence in 1964.4 One of the key questions that this study sought to engage with was: how did the ‘representations’ of Kenneth Kaunda influence the ways in which Zambia’s post-independence nationalist history and national heritage were produced? In seeking to provide an answer to the question, the study evaluated the auto/biography of Kenneth Kaunda itself, as well as how it reflects in the history texts utilised in Zambian schools and in history in the public domain through national heritage sites or monuments and museum exhibitions. The thesis will show that in Zambia, the auto/biography of Kenneth Kaunda has acquired significance through history as school lesson and as history in the public domain, through the production of national heritage sites and museum exhibitions.South Afric
Interview with Kenneth D. Gardner, Jr., M.D
No full textThis interview with Dr. Kenneth D. Gardner, Jr.(1929-), a nephrologist of Albuquerque, New Mexico, and a long-term faculty member of the University of New Mexico School of Medicine, focuses on his career in New Mexico. Among the subjects discussed are Dr. Gardner's personal and professional background; his pioneering and innovative work at UNM-SOM as dean responsible for graduate medical school education at the school; his reflections on the strengths and weaknesses of those programs at UNM-SOM; the development of the school's division of nephrology; and much else
Prenatal care advice to see a dentist: results from a population-based study
No full textMeredith L. Vandermeer (Department of Public Health, Oregon State University), Kenneth D. Rosenberg (Office of Family Health, Oregon Department of Human Services), Alfredo P. Sandoval (Oregon Health & Science University).Title from PDF caption (viewed on August 14, 2020).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode of access: Internet from the Oregon Government Publications Collection.Text in English
An implementation review of an electronic medical record system in a nursing home
No full textCharles Morris is a non-profit healthcare facility run under the auspices of the Jewish Association on Aging (JAA), providing residential, home, and community services in an urban environment. This evaluation was performed in a nursing home containing 159 beds, offering full-service to short and long-term rehabilitation and residents in need of skilled nursing care.\ud
This paper explores the impact of implementing an electronic health record on the quality of resident care in a nursing home, while taking into account nurse hours to resident ratio and the complexity of resident needs. The public health significance of this research is relevant to the senior and elderly population as the nursing home industry is challenged with caring for an increase in aging population while reducing complications from chronic conditions. As the insurance industry becomes more critical of hospital readmissions, acute care facilities will face the burden of dealing with this elderly population and have more incentives to coordinate care plans with nursing homes and their residents. \ud
The review of this implementation has many implications not only internally for the organization but as recommendations for other organizations that are planning to implement their own electronic record system. Quality measures are reported to the state which in turn is published on the internet and made available to the general public. Today, the public can easily access a nursing homes core measures and compare one facilities quality outcomes and nurse staffing to another competitor’s facility. In a competitive environment where nursing homes are vying for patients and higher occupancy rates, company reputation plays a major factor on the overall success of an organization
Long run risks in the term structure of interest rates: estimation
No full textThis paper specifies and estimates a long run risks model with inflation by using the nominal term structure data in the United States from 1953 to 2006. The negative correlation between expected inflation and expected consumption growth in conjunction with the Epstein-Zin (1989) recursive preferences generates an upward sloping yield curve and fits the yield curve data better than the alternative specifications. However, the variations of the forward looking components of consumption growth and inflation in the estimated model are much smaller than implied by calibrated parameter values in the previous literature. An extended model with time varying volatilities alleviates this problem. In the extended model, estimated long run risks and volatilities, especially for inflation, are in line with survey data and the estimated inflation volatility explains a significant portion of the time variation of term premium.
Impact of scour on lateral resistance of wind turbine monopiles: An experimental study
No full textThe majority of offshore wind structures are supported on large-diameter, rigid monopile foundations. These piles may be subjected to scour due to the waves and currents that causes a loss of soil support and consequently decreases the pile capacity and system stiffness. The results of numerical models suggest that the shape of the scour hole affects the magnitude of pile capacity loss; however, there is a dearth of experimental test data that quantify this effect. This paper presents a series of centrifuge model tests on an instrumented model pile that investigates the effects of scour-hole geometry on the response of a laterally loaded pile embedded in sand. The pile instrumentation allowed load–displacement and p–y (soil reaction – displacement) curves to be derived. Three scour geometries (global, local wide, and local narrow) and three scour depths (1D, 1.5D, and 2D; where D is pile diameter) were modelled. For all three scour types, pile moment capacity decreased almost linearly with increase of scour depth. Simple empirical relations were proposed to evaluate the detrimental influence of scour on the pile moment capacity. A new method has been developed to allow designers to quantify the effect of scour-hole shape and severity of scour on the pile response.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Geo-engineerin
The Long-Run Volatility Puzzle of the Real Exchange Rate
No full textThis paper documents large cross-country differences in the long run volatility of the real exchange rate. In particular, it shows that the real exchange rate of developing countries is approximately three times more volatile than the real exchange rate in industrial countries. The paper tests whether this difference in volatility can be explained by the fact that developing countries face larger shocks (both real and nominal) and recurrent currency crises or by different elasticities to these shocks. It finds that the magnitude of the shocks and the differences in elasticities can only explain a small part of the difference in RER volatility between developing and industrial countries. Results from ARCH estimations confirm that there is a substantial difference in long term volatilities between these two sets of countries and indicate that there is also a much higher persistence of deviations of the variance of the RER from its long run value when the economy suffers shocks of various kinds.
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