137 research outputs found
Elimaea (Rectielimaea) percauda Liu
No full text<i>Elimaea (Rectielimaea) percauda</i> Liu C-X & Liu X-W, sp. nov. (Plate 12a, 14a–f, 15a–g) <p> <i>Holotype:</i> male (No. 14011056), China: Guangxi Prov.: Longan, Longhushan Mt., 1995. VIII.29–IX.1, Coll. Liu Xianwei, Jin Xingbao, Zhang Weinian (MSIE).</p> <p> <i>Description:</i> Holotype (male). Tegmen distinctly extending far beyond apex of hind femur; hind wings distinctly longer than tegmen. Tegmen with regular parallel cross veins, costal vein indistinct. Sc and R joining at base, then slightly separate; radius sector branching in basal quarter of tegmen, emitting out 4 branches at apical third. Fore coxae unarmed. Fore femur with 5–6 interior ventral spines; mid femur with 7–11 interior ventral spines; hind femur without ventral spines. Genicular lobes of each femur bispinose. Fore tibiae with 1–3 interior and 0–2 exterior dorsal spines; mid tibiae with 5 interior and 7–9 exterior dorsal spines; hind tibiae with 34 interior and 36 exterior large dorsal spines.</p> <p>Stridulatory file with circa 55 moderately spaced stridulatory teeth, which are gradually becoming larger mediad (Plate 12a). Epiproct long triangular, deflexed, distal quarter part strongly upcurved (Plate 14a, 15f). Cerci long, but not extending to apex of long subgenital plate, deflexed, distinctly incurved, column-like, just gradually acuminated in exterior margin and strongly contracted in interior margin at apex, shaped into a short incurved sharp spine (Plate 14a,f, 15d,g). Subgenital plate long, curved backward in lateral view; basal margin widest, then gradually narrowed toward middle; with subparallel lateral margins in distal half; ventral surface in apical part with angular furrow, not bifurcated, apical margin truncated (Plate 14a,e, 15d,e). Phallus with a long log-like sclerite horizontally produced outwards, dorsally sulcate, slightly curved downwards at apex; each lateral margin with 6 red brown teeth at apex (Plate 14c,d, 15f).</p> <p> <i>Color:</i> Body yellowish green (maybe green at live). Compound eyes dark brown. Antennae with apex of scape and pedical dark brown, and flagella approximately black. Lateral margins of occiput and pronotal disc densely covered with numerous black dots. Longitudinal middle line of pronotal disc rose. Pronotal disc, lateral lobes of pronotum, each abdomen, lateral surface of hind femur densely covered with red brown dots. Ventral surface of fore and mid femor, anterior tibial tympana, and each tarsus dark brown. Spines of each femur and tibia dark brown. Tegminal costal area with a few brown dots of moderate size, each cell between R and M veins with a few brown spots, area near posterior margin densely covered with numerous dark brown dots. Proximal area in tegminal stridulatory area with a large black spot. Apical spine of cerci and teeth of phallus red brown.</p> <p>Female unknown.</p> <p> <i>Measurement of male (mm):</i> length of body 10.5; length of pronotum 4.7; width of pronotal disc at base 2.5; width of pronotal disc at apex 3.0; length of tegmen 31.2; largest width of male stridulatory area 2.5; length of male stridulatory vein 1.8; largest width of dorsal area behind male stridulatory area 1.1; width of mirror on right tegmen 0.7; length of mirror on right tegmen 0.6; distance between basal vein of right tegmen and apex of mirror on right tegmen 1.0; width of tegmen 4.5; length of hind wing 36.8; length of fore femur 7.0; length of fore tibiae 9.2; length of mid femur 11.5; length of mid tibiae 13.4; length of hind femur 23.5; length of hind tibiae 28.5; length of epiproct 2.0; length of cerci 7.9; length of subgenital plate 7.9.</p> <p> <i>Etymology:</i> The name shows that this new species possesses special male abdominal apex.</p> <p> <i>Discussion:</i> This new species most resembles <i>E. (Rhaebelimaea) recta</i> Gorochov, 2009, in shape of the male cerci and structure of the male subgenital plate, but differs by the shape of sharp triangular male epiproct (not with truncate apical margin), length comparison between the male subgenital plate and the male cerci, and the special male genitalia. This new species also resembles <i>Elimaea (Schizelimaea) mira</i> Gorochov, 2009, in the shape of male stridulatory apparatus, but distinctly differs by absence of spine on the upper part of the fore coxae, shape of male subgenital plate, and male phallus.</p> <p> <i>Distribution:</i> China: Guangxi Prov..</p> <p> <b> Subgeus <i>Rhaebelimaea</i> Karny, 1926</b> </p> <p> <i>Elimaea</i> (<i>Rhaebelimaea)</i> Karny, 1926a: 26. Type species: <i>Phaneroptera parumpunctata</i> Serville, 1893, by original designation.</p> <p> <i>Redescription:</i> Male with proximal part of MP+CuIP vein in tegminal dorsal part more or less convex laterad. Most female with subgenital plate transverse, lateral corner of apical margin more or less spinose.</p> <p> <i> <i>Elimaea</i> (<i>Rhaebelimaea</i>) <b>cheni</b></i> Kang & Yang, 1992 (Plate 7a,b)</p> <p> <i>Elimaea (Orthelimaea) cheni</i> Kang and Yang, 1992, Acta Zootaxonomica Sinca 17(3): 327.</p> <p> <i>Material Examined:</i> 4 males (holotype and paratype), 1 female (allotype), China: Hunan Prov.: Dayong, Zhangjiajie, 1985. VII.29, Coll. Chen Naizhong (ICAU); 1 male (paratype), China: Sichuan Prov.: Emeishan Mt., 1961. VIII.27, Coll. Yang Jikun (ICAU); 1 female, 3 males, China: Guizhou Prov., Jiangkou, Fanjingshan, 1985. IX.22, Coll. Liu Xianwei (MSIE); China: Hunan Prov.: 11 females, 12 males, Cili, Suoxiyu, 1988. X.1, Coll. Liu Xianwei (MSIE); 1 female, 2 males, Dayong, Zhangjiajie, Collector unknown (MSIE); 1 male, China: Hubei Prov., Hefeng, 1989. VII.24, Coll. Liu Zuyao, Xie Rongdong (MSIE); China: Sichuan Prov.: 3 females, Ya’an, 1988. IV.10, Coll. Feng Yan (MSIE); 1 male, 1 female, Chongqing, Cuiweishan, 1982. VIII.1, Coll. Wang Tianqi (MSIE); 2 males, Guanxian, 1987. VIII.11, Coll. Liu Xianwei (MSIE); 2 males, Qianjiang, Xiaonanshan, 1989. VII.17, Coll. Xie, He (MSIE); Jingyunshan Mt., 4 males, 3 females, 1991. VIII.7, Coll. Shi Fuming (NAFU); 2 males, 1 female, 1993. VIII.7, Coll. Chenjun (NAFU); Emeishan, 1male, 1987. VIII.11, Coll. Liu Xianwei (MSIE); 1 female, 820m, 1985. VIII.20, Jin Genyao (MSIE); 1 male, 1991. X.1, Coll. Liu Zuyao, Wang Tianqi, Yin Haisheng (MSIE); 1 female, Qingyinge, 800-1000m, 1957. IX.20, Coll. Huang Keren (IZAS); Dujiangyan, 1 female, Liujie, 1991. X.5, Liu Zuyao, Wang Tianqi, Yin Haisheng (MSIE); 1 female, Qingchengshan Mt., 1982. VIII.1, Wang Tianqi (MSIE).</p> <p> <i>Distribution:</i> China: Hunan Prov., Sichuan Prov., Guizhou Prov., Hubei Prov..</p> <p> <b>PLATE 7</b>, Color photograph of <i>Elimaea cheni</i> Kang & Yang (a–b), <i>Elimaea obtusilota</i> Kang & Yang (c–d), <i>Elimaea lii</i> Kang & Yang (e–f), and <i>Elimaea semicirculata</i> Kang & Yang (g–h). a, c, e, g, male left stridulatory area, dorsal view; b, d, f, h, male right stridulatory area, dorsal view.</p>Published as part of <i>Liu, Chun-Xiang & Liu, Xian-Wei, 2011, Elimaea Stål (Orthoptera: Tettigoniidae: Phaneropterinae) and its relative from China, with description of twenty-three new species, pp. 1-48 in Zootaxa 3020</i> on pages 15-17, DOI: <a href="http://zenodo.org/record/278679">10.5281/zenodo.278679</a>
How to introduce demand side resources in the design of low-carbon power systems in China
No full textTopping-off technique prevents aggravation of degeneration of adjacent segment fusion revealed by retrospective and finite element biomechanical analysis
No full textAim: The aim of this study was to evaluate the effect of the Topping-off technique in preventing the aggravation of degeneration caused by adjacent segment fusion. Methods: Clinical parameters of patients who underwent L5-S1 posterior lumbar interbody fusion + interspinous process at L4-L5 (PLIF + ISP) with the Wallis system (Topping-off group) were compared retrospectively with those of patients who underwent solely PLIF. Pre- and post-operative x-ray measurements, visual analogue scale (VAS) scores, and Japanese Orthopaedic Association (JOA) scores were assessed in all subjects. Normal L1-S1 lumbosacral finite element models were established in accordance with the two types of surgery in our study, respectively. Virtual loading was added to assess the motility, disc pressure, and facet joint stress of L4-L5. Results: There were 22 and 23 valid cases included in the Topping-off and PLIF groups. No degeneration was observed in either group. Both VAS and JOA scores improved significantly post-operatively (P < 0.01). The intervertebral angle and lumbar lordosis of L4-L5 were both significantly increased (t = -2.89 and -2.68, P < 0.05 in the Topping-off group and t = -2.25 and -2.15, P < 0.05 in the PLIF group). In the Topping-off group, x-ray in dynamic position showed no significant difference in the angulation or distance of the anterior movement of the L4-L5 segment. The angle of hyper-extension and distance of the posterior movement of L4 were significantly decreased. In the PLIF group, both hyper-flexion and hyper-extension and posterior movement were increased significantly. In finite element analysis, displacement of the L4 vertebral body, pressure of the annulus fibrosus and nucleus pulposus, and stress of the bilateral facet joint were less in the Topping-off group under loads of anterior flexion and posterior extension. Facet joint stress on the left side of the L4-L5 segment was also less in the Topping-off group under left flexion loads. Conclusion: Short-term efficacy and safety between Topping-off and PLIF were similar, whilst the Topping-off technique could restrict the hyper-extension movement of adjacent segments, prevent back and forth movement of proximal vertebrae, and decrease loads of intervertebral disc and facet joints.OrthopedicsSCI(E)[email protected]
Research on service strategy of electricity selling company under the reform of electricity market
No full textLipopolysaccharide in Bile Promotes the Neutrophil Extracellular Traps-Induced Gallstone Formation by Activating the Gallbladder Immune Barrier
No full textJingjing Yu,1,2,* Ziang Meng,1,2,* Xuxu Liu,1,2 Yi Zheng,1,2 Dongbo Xue,1,2 Chenjun Hao,1,2 Liyi Wang1,2 1Department of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150001, People’ s Republic of China; 2Key Laboratory of Hepatosplenic Surgery, Ministry of Education, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150001, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chenjun Hao; Liyi Wang, Email [email protected]; [email protected]: Cholelithiasis areis a common digestive system disorder, with cholesterol gallstones being the most prevalent type. Gallstones lead to many severe complications, posing a significant burden on global healthcare systems. Many studies have shown associations between biliary microbiota, gallbladder immune microenvironment, and gallstone formation. However, the specific immune mechanisms underlying the cholesterol gallstone formation have not been fully elucidated.Methods: In this study, gallbladderand bile samples from 8 asymptomatic patients with cholelithiasis undergoing cholecystectomy and 11 healthy liver transplant donors were collected for tissue transcriptome sequencing and differential analysis. Male C57BL/6J mice were fed a normal or lithogenic diet for 6 weeks. Starting from the third week, lipopolysaccharide (LPS) or specific regulators were injected intraperitoneally once a week for a total of 3 times. Enzyme-linked immunosorbent assay, quantitative polymerase chain reaction, Western blot, immunohistochemistry, and immunofluorescence were employed for quantitative, qualitative or localization analysis of LPS, neutrophil extracellular traps (NETs), inflammatory factors, proteins, and mRNAs using samples collected from mice.Results: In patients with cholelithiasis, the gallbladder mechanical barrier is impaired, resulting in an immune-activated state. LPS induces damage to the gallbladder mucosal mechanical barrier through the Toll-like receptor 4 (TLR4)/myeloid differentiation factor 88 (MyD88)/nuclear factor kappa-B (NF-κB) signaling pathway. Furthermore, it stimulates the continuous production of NETs through the TLR4/Phosphoinositide 3-kinase (PI3K)/Protein kinase B (Akt) signaling pathway, aggravating the formation of gallstones.Conclusion: With the biliary dysbiosis, excessive LPS can invade the submucosa of the gallbladder, leading to chronic inflammation that recruits neutrophils to form NETs, which are ultimately expelled into bile, thereby promoting the formation of gallstones. Keywords: gallstone, lipopolysaccharide, immune barrier, neutrophil extracellular trap
Filamentation and inhibition of prokaryotic CTP synthase with ligands
No full textCytidine triphosphate synthase (CTPS) plays a pivotal role in the de novo synthesis of cytidine triphosphate (CTP), a fundamental building block for RNA and DNA that is essential for life. CTPS is capable of directly binding to all four nucleotide triphosphates: adenine triphosphate, uridine triphosphate, CTP, and guanidine triphosphate. Furthermore, CTPS can form cytoophidia in vivo and metabolic filaments in vitro, undergoing regulation at multiple levels. CTPS is considered a potential therapeutic target for combating invasions or infections by viral or prokaryotic pathogens. Utilizing cryo‐electron microscopy, we determined the structure of Escherichia coli CTPS (ecCTPS) filament in complex with CTP, nicotinamide adenine dinucleotide (NADH), and the covalent inhibitor 6‐diazo‐5‐oxo‐ l‐norleucine (DON), achieving a resolution of 2.9 Å. We constructed a phylogenetic tree based on differences in filament‐forming interfaces and designed a variant to validate our hypothesis, providing an evolutionary perspective on CTPS filament formation. Our computational analysis revealed a solvent‐accessible ammonia tunnel upon DON binding. Through comparative structural analysis, we discern a distinct mode of CTP binding of ecCTPS that differs from eukaryotic counterparts. Combining biochemical assays and structural analysis, we determined and validated the synergistic inhibitory effects of CTP with NADH or adenine on CTPS. Our results expand our comprehension of the diverse regulatory aspects of CTPS and lay a foundation for the design of specific inhibitors targeting prokaryotic CTPS
Crosstalk Prediction with Normalized Huygens’s Equivalent Model in High Speed Transceiver
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